메뉴 건너뛰기




Volumn 16, Issue 1, 2011, Pages 1-6

Effects of expression of lcb1/lcb2 and lac1/lag1 genes on the biosynthesis of ceramides

Author keywords

Ceramides; Metabolic engineering; Saccharomyces cerevisiae; Sphingolipid synthesis pathway

Indexed keywords

CELL EXTRACTS; CELL-CYCLE ARREST; CERAMIDE SYNTHASE; CERAMIDES; CO-EXPRESSION; HYDROXYLASES; METABOLIC ENGINEERING; S.CEREVISIAE; SERINE PALMITOYLTRANSFERASES; SPHINGOLIPIDS; SYNTHESIS PATHWAYS;

EID: 84863010980     PISSN: 12268372     EISSN: 19763816     Source Type: Journal    
DOI: 10.1007/s12257-010-0268-8     Document Type: Article
Times cited : (4)

References (33)
  • 1
    • 33748309395 scopus 로고    scopus 로고
    • Functions and metabolism of sphingolipids in Saccharomyces cerevisiae
    • DOI 10.1016/j.plipres.2006.03.004, PII S016378270600021X
    • Dickson, R. C., C. Sumanasekera, and R. L. Lester (2006) Functions and metabolism of sphingolipids in Saccharomyces cerevisiae. Prog. Lipid Res. 45:447-465. (Pubitemid 44331410)
    • (2006) Progress in Lipid Research , vol.45 , Issue.6 , pp. 447-465
    • Dickson, R.C.1    Sumanasekera, C.2    Lester, R.L.3
  • 2
    • 33947238877 scopus 로고    scopus 로고
    • Yeast sphingolipids: Recent developments in understanding biosynthesis, regulation, and function
    • DOI 10.1016/j.bbalip.2006.08.005, PII S1388198106002265, Regulation of Lipid Metabolism in Yeast
    • Cowart, L. A. and L. M. Obeid (2007) Yeast sphingolipids: recent developments in understanding biosynthesis, regulation, and function. Biochim. Biophys. Acta 1771:421-431. (Pubitemid 46428614)
    • (2007) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol.1771 , Issue.3 , pp. 421-431
    • Cowart, L.A.1    Obeid, L.M.2
  • 5
    • 0031919157 scopus 로고    scopus 로고
    • Regulation of ceramide production and apoptosis
    • Kolesnick, R. N. and M. Kronke (1998) Regulation of ceramide production and apoptosis. Annu. Rev. Physiol. 60:643-665.
    • (1998) Annu. Rev. Physiol. , vol.60 , pp. 643-665
    • Kolesnick, R.N.1    Kronke, M.2
  • 7
    • 0030971056 scopus 로고    scopus 로고
    • Selective involvement of ceramide in cytokine-induced apoptosis: Ceramide inhibits phorbol ester activation of nuclear factor B
    • DOI 10.1074/jbc.272.26.16474
    • Gamard, C. J., G. S. Dbaibo, B. Liu, L. M. Obeid, and Y. A. Hannun (1997) Selective involvement of ceramide in cytokineinduced apoptosis. Ceramide inhibits phorbol ester activation of nuclear factor kappa B. J. Biol. Chem. 272:16474-16481. (Pubitemid 27276474)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.26 , pp. 16474-16481
    • Gamard, C.J.1    Dbaibo, G.S.2    Liu, B.3    Obeid, L.M.4    Hannun, Y.A.5
  • 9
    • 0038273238 scopus 로고    scopus 로고
    • Isolation and chemical composition of the ceramide of the Candida lipolytica yeast
    • DOI 10.1016/S0009-3084(97)00106-0, PII S0009308497001060
    • Rupeic, J. and V. Maric (1998) Isolation and chemical composition of the ceramide of the Candida lipolytica yeast. Chem. Phys. Lipids 91:153-161. (Pubitemid 28142963)
    • (1998) Chemistry and Physics of Lipids , vol.91 , Issue.2 , pp. 153-161
    • Rupcic, J.1    Maric, V.2
  • 13
    • 0035942309 scopus 로고    scopus 로고
    • Enzymes of sphingolipid metabolism: From modular to integrative signaling
    • DOI 10.1021/bi002836k
    • Hannun, Y. A., C. Luberto, and K. M. Argraves (2001) Enzymes of sphingolipid metabolism: From modular to integrative signaling. Biochem. 40:4893-4903. (Pubitemid 32332534)
    • (2001) Biochemistry , vol.40 , Issue.16 , pp. 4893-4903
    • Hannun, Y.A.1    Luberto, C.2    Argraves, K.M.3
  • 14
    • 0037168471 scopus 로고    scopus 로고
    • Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae
    • DOI 10.1021/bi026616d
    • Funato, K., B. Vallee, and H. Riezman (2002) Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae. Biochem. 41:15105-15114. (Pubitemid 36008117)
    • (2002) Biochemistry , vol.41 , Issue.51 , pp. 15105-15114
    • Funato, K.1    Vallee, B.2    Riezman, H.3
  • 15
    • 77649226199 scopus 로고    scopus 로고
    • Effect of expression of genes in the sphingolipid synthesis pathway on the biosynthesis of ceramide in Saccharomyces cerevisiae
    • Kim, S. K., Y. H. Noh, J.-R. Koo, and H. S. Yun (2010) Effect of expression of genes in the sphingolipid synthesis pathway on the biosynthesis of ceramide in Saccharomyces cerevisiae. J. Microbiol. Biotechnol. 20:356-362.
    • (2010) J. Microbiol. Biotechnol. , vol.20 , pp. 356-362
    • Kim, S.K.1    Noh, Y.H.2    Koo, J.-R.3    Yun, H.S.4
  • 16
    • 0034677919 scopus 로고    scopus 로고
    • Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity
    • DOI 10.1074/jbc.275.11.7597
    • Gable, K., H. Slife, D. Bacikova, E. Monaghan, and T. Dunn (2000) Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity. J. Biol. Chem. 275:7597-7603. (Pubitemid 30159659)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.11 , pp. 7597-7603
    • Gable, K.1    Slife, H.2    Bacikova, D.3    Monaghan, E.4    Dunn, T.M.5
  • 17
    • 0035355508 scopus 로고    scopus 로고
    • C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p
    • DOI 10.1093/emboj/20.11.2655
    • Guillas, I., P. A. Kirchman, R. Chuard, M. Pfefferli, J. C. Jiang, S. M. Jazwinski, and A. Conzelmann (2001) C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p. EMBO J. 20:2655-2665. (Pubitemid 32938550)
    • (2001) EMBO Journal , vol.20 , Issue.11 , pp. 2655-2665
    • Guillas, I.1    Kirchman, P.A.2    Chuard, R.3    Pfefferli, M.4    Jiang, J.C.5    Jazwinski, S.M.6    Conzelmann, A.7
  • 18
    • 0036275447 scopus 로고    scopus 로고
    • Getting started with yeast
    • DOI 10.1016/S0076-6879(02)50954-X
    • Sherman, F. (2002) Getting Started with Yeast. pp. 3-41. In: C. Guthrie and G. R. Fink (eds.). Methods in Enzymology: Guide to Yeast Genetics and Molecular and Cell Biology, Academic Press, San Diego, California. (Pubitemid 34619482)
    • (2002) Methods in Enzymology , vol.350 , pp. 3-41
    • Sherman, F.1
  • 19
    • 77649194995 scopus 로고    scopus 로고
    • The ceramide contents of Saccharomyces cerevisiae in batch culture
    • Kim, S. K., Y. H. Noh, and H. S. Yun (2008) The ceramide contents of Saccharomyces cerevisiae in batch culture. Kor. J. Biotechnol. Bioeng. 23:449-451.
    • (2008) Kor. J. Biotechnol. Bioeng. , vol.23 , pp. 449-451
    • Kim, S.K.1    Noh, Y.H.2    Yun, H.S.3
  • 21
    • 84863022148 scopus 로고    scopus 로고
    • www.yeastgenome.org.
  • 22
    • 0036270543 scopus 로고    scopus 로고
    • Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method
    • DOI 10.1016/S0076-6879(02)50957-5
    • Gietz, R. D. and R. A. Woods (2002) Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. pp. 87-96. In: C. Guthrie and G. R. Fink (eds.). Methods in Enzymology: Guide to Yeast Genetics and Molecular and Cell Biology. Academic Press, San Diego, California. (Pubitemid 34619485)
    • (2002) Methods in Enzymology , vol.350 , pp. 87-96
    • Gietz, R.D.1    Woods, R.A.2
  • 23
    • 24344473567 scopus 로고    scopus 로고
    • Mobile phase compositions for ceramide III by normal phase high performance liquid chromatography
    • Hong, S. P., C. H. Lee, S. K. Kim, H. S. Yun, J. H. Lee, and K. H. Row (2004) Mobile phase compositions for ceramide III by normal phase high performance liquid chromatography. Biotechnol. Bioproc. Eng. 9:47-51.
    • (2004) Biotechnol. Bioproc. Eng. , vol.9 , pp. 47-51
    • Hong, S.P.1    Lee, C.H.2    Kim, S.K.3    Yun, H.S.4    Lee, J.H.5    Row, K.H.6
  • 24
    • 0037280211 scopus 로고    scopus 로고
    • Quantitative analysis of ceramide III of Saccharomyces cerevisiae by normal phase HPLC
    • DOI 10.1081/JLC-120017910
    • Kang, D. H., S. P. Hong, and K. H. Row (2003) Quantitative analysis of ceramide III of Saccharomyces cerevisiae by normal phase HPLC. J. Liq. Chromatogr. Relat. Technol. 26:617-627. (Pubitemid 36236895)
    • (2003) Journal of Liquid Chromatography and Related Technologies , vol.26 , Issue.4 , pp. 617-627
    • Kang, D.H.1    Hong, S.P.2    Row, K.H.3
  • 25
    • 0026111223 scopus 로고
    • Influence of plasmid origin and promoter strength in fermentations of recombinant yeast
    • Da Silva, N. A. and J. E. Bailey (1991) Influence of plasmid origin and promoter strength in fermentations of recombinant yeast. Biotechnol. Bioeng. 37:318-324.
    • (1991) Biotechnol. Bioeng. , vol.37 , pp. 318-324
    • Da Silva, N.A.1    Bailey, J.E.2
  • 26
    • 0007836534 scopus 로고    scopus 로고
    • Expression and secretion of recombinant Inulinase under the control of GAL or GAP promoter in Saccharomyces cerevisiae
    • Nam, S. W., H. J. Lim, B. H. Chung, and Y. K. Chang (1996) Expression and secretion of recombinant Inulinase under the control of GAL or GAP promoter in Saccharomyces cerevisiae. Kor. J. Biotechnol. Bioeng. 11:445-452.
    • (1996) Kor. J. Biotechnol. Bioeng. , vol.11 , pp. 445-452
    • Nam, S.W.1    Lim, H.J.2    Chung, B.H.3    Chang, Y.K.4
  • 28
    • 3242673409 scopus 로고    scopus 로고
    • Suppressor analysis points to the subtle role of the LAG1 ceramide synthase gene in determining yeast longevity
    • DOI 10.1016/j.exger.2004.03.026, PII S0531556504001305
    • Jiang, J. C., P. A. Kirchman, M. Allen, and S. M. Jazwinski (2004) Suppressor analysis points to the subtle role of the LAG1 ceramide synthase gene in determining yeast longevity. Exp. Gerontol. 39:999-1009. (Pubitemid 38952880)
    • (2004) Experimental Gerontology , vol.39 , Issue.7 , pp. 999-1009
    • Jiang, J.C.1    Kirchman, P.A.2    Allen, M.3    Jazwinski, S.M.4
  • 29
    • 4143101352 scopus 로고    scopus 로고
    • Differential regulation of ceramide synthase components LAC1 and LAG1 in Saccharomyces cerevisiae
    • DOI 10.1128/EC.3.4.880-892.2004
    • Kolaczkowski, M., A. Kolaczkowska, B. Gaigg, R. Schneiter, and W. S. Moye-Rowley (2004) Differential regulation of ceramide synthase components LAC1 and LAG1 in Saccharomyces cerevisiae Eukaryot. Cell 3:880-892. (Pubitemid 39098864)
    • (2004) Eukaryotic Cell , vol.3 , Issue.4 , pp. 880-892
    • Kolaczkowski, M.1    Kolaczkowska, A.2    Gaigg, B.3    Schneiter, R.4    Moye-Rowley, W.S.5
  • 30
    • 1942508133 scopus 로고    scopus 로고
    • Cloning and functional characterization of the SUR2/SYR2 gene encoding sphinganine hydroxylase in Pichia ciferrii
    • Bae, J. H., J. H. Sohn, C. S. Park, J. S. Rhee, and E. S. Choi (2004) Cloning and functional characterization of the SUR2/SYR2 gene encoding sphinganine hydroxylase in Pichia ciferrii. Yeast 21:437-443.
    • (2004) Yeast , vol.21 , pp. 437-443
    • Bae, J.H.1    Sohn, J.H.2    Park, C.S.3    Rhee, J.S.4    Choi, E.S.5
  • 31
    • 0032080333 scopus 로고    scopus 로고
    • Syringomycin action gene SYR2 is essential for sphingolipid 4- hydroxylation in Saccharomyces cerevisiae
    • DOI 10.1074/jbc.273.18.11062
    • Grilley, M. M., S. D. Stock, R. C. Dickson, R. L. Lester, and J. Y. Takemoto (1998) Syringomycin action gene SYR2 Is essential for sphingolipid 4-Hydroxylation in Saccharomyces cerevisiae. J. Biol. Chem. 273:11062-11068. (Pubitemid 28204951)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.18 , pp. 11062-11068
    • Grilley, M.M.1    Stock, S.D.2    Dickson, R.C.3    Lester, R.L.4    Takemoto, J.Y.5
  • 33
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • -ΔΔCT method. Methods 25:402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.