Lack of association between essential hypertension and GSTO1 uncommon genetic variants in Italian patients

Genetic Testing and Molecular Biomarkers

Volumn 16, Issue 6, 2012, Pages 615-620

  Polimanti, Renato ^a,b   Piacentini, Sara ^a   Lazzarin, Natalia ^b   Re, Maria Antonietta ^b   Manfellotto, Dario ^b   Fuciarelli, Maria ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAN GIOVANNI CALIBITA FATEBENEFRATELLI HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CARDIOVASCULAR RISK; DIAGNOSTIC TEST ACCURACY STUDY; ESSENTIAL HYPERTENSION; FEMALE; GENE; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GLUTATHIONE S TRANSFERASE OMEGA 1 GENE; HAPLOTYPE; HUMAN; HUMAN CELL; ITALY; MAJOR CLINICAL STUDY; MALE;

EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENOTYPE; GLUTATHIONE TRANSFERASE; HAPLOTYPES; HUMANS; HYPERTENSION; ITALY; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; SEX FACTORS;

EID: 84862991083     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2011.0310     Document Type: Article

References (40)

1. Adeyemo A, Gerry N, Chen G, et al. (2009) A genome-wide association study of hypertension and blood pressure in African Americans. PLoS Genet 5:e1000564.
2. Agusa T, Iwata H, Fujihara J, et al. (2010) Genetic polymorphisms in glutathione S-transferase (GST) superfamily and arsenic metabolismin residents of the Red River Delta, Vietnam. Toxicol Appl Pharmacol 242:352-362.
3. Barrett JC, Fry B, Maller J, et al. (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265. (Pubitemid 40202029)
4. Bessa SS, Ali EM, Hamdy SM (2009) The role of glutathione Stransferase M1 and T1 gene polymorphisms and oxidative stress related parameters in Egyptian patients with essential hypertension. Eur J Intern Med 20:625-630.
5. Board PG (2011) The omega-class glutathione transferases: structure, function, and genetics. Drug Metab Rev 43:226-235.
6. Board PG, Anders MW (2007) Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones. Chem Res Toxicol 20:149-154. (Pubitemid 46220165)
7. Board PG, Coggan M, Cappello J, et al. (2008) S-(4-Nitrophenacyl) glutathione is a specific substrate for glutathione transferase omega 1-1. Anal Biochem 374:25-30.
8. Bodmer W, Bonilla C (2008) Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet 40:695-701. (Pubitemid 351748875)
9. Budowle B, Moretti T, Smith J, et al. (2000) DNA Typing Protocols: Molecular Biology and Forensic Analysis. A Bio- Techniques Books Publications. Eaton Publishing,
10. Natick, MA. Capoluongo E, Onder G, Concolino P, et al. (2009) GSTM1-null polymorphism as possible risk marker for hypertension: Results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study). Clin Chim Acta 399:92-96.
11. Chen Y, Graziano JH, Parvez F, et al. (2011) Arsenic exposure from drinking water and mortality from cardiovascular disease in Bangladesh: prospective cohort study. BMJ 342:d2431.
12. Delles C, Padmanabhana S, Lee WK, et al. (2008) Glutathione Stransferase variants and hypertension. J Hypertens 26:1343-1352.
13. Doney AS, Lee S, Leese GP, et al. (2005) Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go- DARTS study. Circulation 111:2927-2934. (Pubitemid 40814185)
14. Dulhunty A, Gage P, Curtis S, et al. (2001) The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator. J Biol Chem 276:3319-3323.
15. Ehret GB (2010) Genome-wide association studies: contribution of genomics to understanding blood pressure and essential hypertension. Curr Hypertens Rep 12:17-25.
16. Greenacre M (1992) Correspondence analysis in medical research. Stat Methods Med Res 1:97-117.
17. Hindorff LA, Junkins HA, Hall PN, et al. (2011) A Catalog of Published Genome-Wide Association Studies. Available at www.genome.gov/gwastudies.
18. Khawaja MR, Taj F, Saleheen D, et al. (2008) Association study of two interleukin-1 gene loci with essential hypertension in a Pakistani Pathan population. J Hum Hypertens 22:60-62. (Pubitemid 350269259)
19. Kraja AT, Hunt SC, Rao DC, et al. (2011) Genetics of hypertension and cardiovascular disease and their interconnected pathways: lessons from large studies. Curr Hypertens Rep 13:46-54.
20. Laliberte RE, Perregaux DG, Hoth LR, et al. (2003) Glutathione stransferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin- 1beta posttranslational processing. J Biol Chem 278:16567-16568.
21. Manolio TA, Collins FS, Cox NJ, et al. (2009) Finding the missing heritability of complex diseases. Nature 461:747-753.
22. Marinho C, Alho I, Arduino D, et al. (2007) GST M1/T1 and MTHFR polymorphisms as risk factors for hypertension. Biochem Biophys Res Commun 353:344-350. (Pubitemid 46014571)
23. Marnell LL, Garcia-Vargas GG, Chowdhury UK, et al. (2003) Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profiles. Chem Res Toxicol 16:1507-1513. (Pubitemid 38049369)
24. Menashe I, Rosenberg PS, Chen BE (2008) PGA: power calculator for case-control genetic association analyses. BMC Genet 9:36.
25. Mukherjee B, Salavaggione OE, Pelleymounter LL, et al. (2006) Glutathione S-transferase omega 1 and omega 2 pharmacogenomics. Drug Metab Dispos 34:1237-1246.
26. Oniki K, Hori M, Takata K, et al. (2004) Association between glutathione S-transferase A1, M1 and T1 polymorphisms and hypertension. Pharmacogenet Genomics 18:275-277.
27. Piacentini S, Polimanti R, Moscatelli B, et al. (2010) Glutathione S-transferase gene polymorphisms and air pollution as interactive risk factors for asthma in a multicentre Italian field study: a preliminary study. Ann Hum Biol 37:427-439.
28. Piacentini S, Polimanti R, Porreca F, et al. (2011) GSTT1 and GSTM1 gene polymorphisms in European and African populations. Mol Biol Rep 38:1225-1230.
29. Polimanti R, Piacentini S, De Angelis F, et al. (2011a) Human GST loci as markers of evolutionary forces: GSTO1*E155del and GSTO1*E208K polymorphisms may be under natural selection induced by environmental arsenic. Dis Markers 31:231-239.
30. Polimanti R, Piacentini S, Fuciarelli M (2011b) HapMap-based study of human soluble glutathione S-transferase enzymes: the role of natural selection in shaping the single nucleotide polymorphism diversity of xenobiotic- metabolizing genes. Pharmacogenet Genomics 21:665-672.
31. Polimanti R, Piacentini S, Lazzarin N, et al. (2011c) Glutathione S-transferase variants as risk factor for essential hypertension in Italian patients. Mol Cell Biochem 357:227-233.
32. Polimanti R, Piacentini S, Moscatelli B, et al. (2010a) GSTA1, GSTO1 and GSTO2 gene polymorphisms in Italian asthma patients. Clin Exp Pharmacol Physiol 37:870-872.
33. Polimanti R, Piacentini S, Porreca F, et al. (2010b) Glutathione Stransferase o class (GSTO) polymorphisms in a sample from Rome (Central Italy). Ann Hum Biol 37:585-592.
34. Rybka J, Kupczyk D, Kȩdziora-Kornatowska K, et al. (2011) Glutathione-related antioxidant defense system in elderly patients treated for hypertension. Cardiovasc Toxicol 11:1-9.
35. Sampson J, Jacobs K, Yeager M, et al. (2011) Efficient study design for next generation sequencing. Genet Epidemiol DOI:10.1002/gepi.20575.
36. Solé X, Guino E, Valls J, et al. (2006) SNPStats: a web tool for the analysis of association studies. Bioinformatics 22:1928-1929. (Pubitemid 44283043)
37. Tamer L, Ercan B, Camsari A, et al. (2004) Glutathione S-transferase gene polymorphism as a susceptibility factor in smoking- related coronary artery disease. Basic Res Cardiol 99: 223-229. (Pubitemid 38594230)
38. Thier R, Brüning T, Roos PH, et al. (2003) Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes. Int J Hyg Environ Health 206:149-171. (Pubitemid 36807091)
39. Whitbread AK, Masoumi A, Tetlow N, et al. (2005) Characterization of the omega class of glutathione transferases. Methods Enzymol 401:78-99. (Pubitemid 43052387)
40. Zhou H, Brock J, Casarotto MG, et al. (2011) Novel folding and stability defects cause a deficiency of human glutathione transferase omega 1. J Biol Chem 286:4271-4279.