-
1
-
-
33747777758
-
PPARgamma as a new therapeutic target in inflammatory bowel diseases
-
Dubuquoy L, Rousseaux C, Thuru X, Peyrin-Biroulet L, Romano O, et al. (2006) PPARgamma as a new therapeutic target in inflammatory bowel diseases. Gut 55: 1341-1349.
-
(2006)
Gut
, vol.55
, pp. 1341-1349
-
-
Dubuquoy, L.1
Rousseaux, C.2
Thuru, X.3
Peyrin-Biroulet, L.4
Romano, O.5
-
2
-
-
0029154635
-
Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor gamma
-
Tontonoz P, Hu E, Spiegelman BM, (1995) Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor gamma. Curr Opin Genet Dev 5: 571-576.
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 571-576
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
3
-
-
47349107464
-
The Role of PPAR Ligands in Controlling Growth-Related Gene Expression and their Interaction with Lipoperoxidation Products
-
Barrera G, Toaldo C, Pizzimenti S, Cerbone A, Pettazzoni P, et al. (2008) The Role of PPAR Ligands in Controlling Growth-Related Gene Expression and their Interaction with Lipoperoxidation Products. PPAR Res 2008: 524671.
-
(2008)
PPAR Res
, vol.2008
, pp. 524671
-
-
Barrera, G.1
Toaldo, C.2
Pizzimenti, S.3
Cerbone, A.4
Pettazzoni, P.5
-
4
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
-
Forman BM, Chen J, Evans RM, (1997) Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A 94: 4312-4317.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 4312-4317
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
5
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, et al. (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 270: 12953-12956.
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
-
6
-
-
28944446431
-
The many faces of PPARgamma
-
Lehrke M, Lazar MA, (2005) The many faces of PPARgamma. Cell 123: 993-999.
-
(2005)
Cell
, vol.123
, pp. 993-999
-
-
Lehrke, M.1
Lazar, M.A.2
-
7
-
-
0031013395
-
Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs
-
Lehmann JM, Lenhard JM, Oliver BB, Ringold GM, Kliewer SA, (1997) Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem 272: 3406-3410.
-
(1997)
J Biol Chem
, vol.272
, pp. 3406-3410
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
Ringold, G.M.4
Kliewer, S.A.5
-
8
-
-
34547843591
-
Expression of peroxisome proliferator-activated receptor-gamma in colon cancer: correlation with histopathological parameters, cell cycle-related molecules, and patients' survival
-
Theocharis S, Giaginis C, Parasi A, Margeli A, Kakisis J, et al. (2007) Expression of peroxisome proliferator-activated receptor-gamma in colon cancer: correlation with histopathological parameters, cell cycle-related molecules, and patients' survival. Dig Dis Sci 52: 2305-2311.
-
(2007)
Dig Dis Sci
, vol.52
, pp. 2305-2311
-
-
Theocharis, S.1
Giaginis, C.2
Parasi, A.3
Margeli, A.4
Kakisis, J.5
-
9
-
-
62949100452
-
Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis
-
Ogino S, Shima K, Baba Y, Nosho K, Irahara K, et al. (2009) Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis. Gastroenterology 136: 1242-1250.
-
(2009)
Gastroenterology
, vol.136
, pp. 1242-1250
-
-
Ogino, S.1
Shima, K.2
Baba, Y.3
Nosho, K.4
Irahara, K.5
-
10
-
-
0042887520
-
Potential role for peroxisome proliferator activated receptor (PPAR) in preventing colon cancer
-
Jackson L, Wahli W, Michalik L, Watson SA, Morris T, et al. (2003) Potential role for peroxisome proliferator activated receptor (PPAR) in preventing colon cancer. Gut 52: 1317-1322.
-
(2003)
Gut
, vol.52
, pp. 1317-1322
-
-
Jackson, L.1
Wahli, W.2
Michalik, L.3
Watson, S.A.4
Morris, T.5
-
11
-
-
33749633136
-
Intestinal-specific PPARgamma deficiency enhances tumorigenesis in ApcMin/+ mice
-
McAlpine CA, Barak Y, Matise I, Cormier RT, (2006) Intestinal-specific PPARgamma deficiency enhances tumorigenesis in ApcMin/+ mice. Int J Cancer 119: 2339-2346.
-
(2006)
Int J Cancer
, vol.119
, pp. 2339-2346
-
-
McAlpine, C.A.1
Barak, Y.2
Matise, I.3
Cormier, R.T.4
-
12
-
-
16644393169
-
Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, inhibits growth and metastasis of HT-29 human colon cancer cells through differentiation-promoting effects
-
Yoshizumi T, Ohta T, Ninomiya I, Terada I, Fushida S, et al. (2004) Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, inhibits growth and metastasis of HT-29 human colon cancer cells through differentiation-promoting effects. Int J Oncol 25: 631-639.
-
(2004)
Int J Oncol
, vol.25
, pp. 631-639
-
-
Yoshizumi, T.1
Ohta, T.2
Ninomiya, I.3
Terada, I.4
Fushida, S.5
-
13
-
-
33745095265
-
1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARgamma-dependent and PPARgamma-independent pathways
-
Chintharlapalli S, Papineni S, Safe S, (2006) 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARgamma-dependent and PPARgamma-independent pathways. Mol Cancer Ther 5: 1362-1370.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1362-1370
-
-
Chintharlapalli, S.1
Papineni, S.2
Safe, S.3
-
14
-
-
33646269042
-
Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis
-
Marin HE, Peraza MA, Billin AN, Willson TM, Ward JM, et al. (2006) Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis. Cancer Res 66: 4394-4401.
-
(2006)
Cancer Res
, vol.66
, pp. 4394-4401
-
-
Marin, H.E.1
Peraza, M.A.2
Billin, A.N.3
Willson, T.M.4
Ward, J.M.5
-
15
-
-
80055076022
-
Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands
-
Chacko BK, Scott DW, Chandler RT, Patel RP, (2011) Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands. J Biol Chem 286: 38738-38747.
-
(2011)
J Biol Chem
, vol.286
, pp. 38738-38747
-
-
Chacko, B.K.1
Scott, D.W.2
Chandler, R.T.3
Patel, R.P.4
-
16
-
-
54949147269
-
Inhibition of peroxisome proliferator-activated receptor gamma activity suppresses pancreatic cancer cell motility
-
Nakajima A, Tomimoto A, Fujita K, Sugiyama M, Takahashi H, et al. (2008) Inhibition of peroxisome proliferator-activated receptor gamma activity suppresses pancreatic cancer cell motility. Cancer Sci 99: 1892-1900.
-
(2008)
Cancer Sci
, vol.99
, pp. 1892-1900
-
-
Nakajima, A.1
Tomimoto, A.2
Fujita, K.3
Sugiyama, M.4
Takahashi, H.5
-
17
-
-
28044446581
-
PPARgamma-dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF)
-
Cimini A, Cristiano L, Colafarina S, Benedetti E, Di Loreto S, et al. (2005) PPARgamma-dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF). Int J Cancer 117: 923-933.
-
(2005)
Int J Cancer
, vol.117
, pp. 923-933
-
-
Cimini, A.1
Cristiano, L.2
Colafarina, S.3
Benedetti, E.4
Di Loreto, S.5
-
18
-
-
14544272384
-
Phosphorylation of PPARs: from molecular characterization to physiological relevance
-
Diradourian C, Girard J, Pegorier JP, (2005) Phosphorylation of PPARs: from molecular characterization to physiological relevance. Biochimie 87: 33-38.
-
(2005)
Biochimie
, vol.87
, pp. 33-38
-
-
Diradourian, C.1
Girard, J.2
Pegorier, J.P.3
-
19
-
-
33845221920
-
Control of peroxisome proliferator-activated receptor fate by the ubiquitinproteasome system
-
Genini D, Catapano CV, (2006) Control of peroxisome proliferator-activated receptor fate by the ubiquitinproteasome system. J Recept Signal Transduct Res 26: 679-692.
-
(2006)
J Recept Signal Transduct Res
, vol.26
, pp. 679-692
-
-
Genini, D.1
Catapano, C.V.2
-
20
-
-
7944236265
-
The transactivating function of peroxisome proliferator-activated receptor gamma is negatively regulated by SUMO conjugation in the amino-terminal domain
-
Yamashita D, Yamaguchi T, Shimizu M, Nakata N, Hirose F, et al. (2004) The transactivating function of peroxisome proliferator-activated receptor gamma is negatively regulated by SUMO conjugation in the amino-terminal domain. Genes Cells 9: 1017-1029.
-
(2004)
Genes Cells
, vol.9
, pp. 1017-1029
-
-
Yamashita, D.1
Yamaguchi, T.2
Shimizu, M.3
Nakata, N.4
Hirose, F.5
-
21
-
-
33846590071
-
Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma
-
Burgermeister E, Chuderland D, Hanoch T, Meyer M, Liscovitch M, et al. (2007) Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Mol Cell Biol 27: 803-817.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 803-817
-
-
Burgermeister, E.1
Chuderland, D.2
Hanoch, T.3
Meyer, M.4
Liscovitch, M.5
-
22
-
-
34548289084
-
MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma
-
Burgermeister E, Seger R, (2007) MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma. Cell Cycle 6: 1539-1548.
-
(2007)
Cell Cycle
, vol.6
, pp. 1539-1548
-
-
Burgermeister, E.1
Seger, R.2
-
23
-
-
0032894240
-
c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-gamma1 and negatively regulates its transcriptional activity
-
Camp HS, Tafuri SR, Leff T, (1999) c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-gamma1 and negatively regulates its transcriptional activity. Endocrinology 140: 392-397.
-
(1999)
Endocrinology
, vol.140
, pp. 392-397
-
-
Camp, H.S.1
Tafuri, S.R.2
Leff, T.3
-
24
-
-
3843090683
-
Inhibition of c-Jun N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats
-
Ferrandi C, Ballerio R, Gaillard P, Giachetti C, Carboni S, et al. (2004) Inhibition of c-Jun N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats. Br J Pharmacol 142: 953-960.
-
(2004)
Br J Pharmacol
, vol.142
, pp. 953-960
-
-
Ferrandi, C.1
Ballerio, R.2
Gaillard, P.3
Giachetti, C.4
Carboni, S.5
-
25
-
-
0015822275
-
Culture of human endothelial cells derived from umbilical veins
-
Jaffe EA, Nachman RL, Becker CG, Minick CR, (1973) Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria J Clin Invest 52: 2745-2756.
-
(1973)
Identification by Morphologic and Immunologic Criteria J Clin Invest
, vol.52
, pp. 2745-2756
-
-
Jaffe, E.A.1
Nachman, R.L.2
Becker, C.G.3
Minick, C.R.4
-
26
-
-
0042168895
-
Substance P increases neutrophil adhesion to human umbilical vein endothelial cells
-
Dianzani C, Collino M, Lombardi G, Garbarino G, Fantozzi R, (2003) Substance P increases neutrophil adhesion to human umbilical vein endothelial cells. Br J Pharmacol 139: 1103-1110.
-
(2003)
Br J Pharmacol
, vol.139
, pp. 1103-1110
-
-
Dianzani, C.1
Collino, M.2
Lombardi, G.3
Garbarino, G.4
Fantozzi, R.5
-
27
-
-
33746080426
-
Genome-wide identification of peroxisome proliferator response elements using integrated computational genomics
-
Lemay DG, Hwang DH, (2006) Genome-wide identification of peroxisome proliferator response elements using integrated computational genomics. J Lipid Res 47: 1583-1587.
-
(2006)
J Lipid Res
, vol.47
, pp. 1583-1587
-
-
Lemay, D.G.1
Hwang, D.H.2
-
28
-
-
57649200412
-
Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}
-
Reddy RC, Narala VR, Keshamouni VG, Milam JE, Newstead MW, et al. (2008) Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}. Blood 112: 4250-4258.
-
(2008)
Blood
, vol.112
, pp. 4250-4258
-
-
Reddy, R.C.1
Narala, V.R.2
Keshamouni, V.G.3
Milam, J.E.4
Newstead, M.W.5
-
29
-
-
0142055892
-
The role of fibrinogen and related fragments in tumour angiogenesis and metastasis
-
Staton CA, Brown NJ, Lewis CE, (2003) The role of fibrinogen and related fragments in tumour angiogenesis and metastasis. Expert Opin Biol Ther 3: 1105-1120.
-
(2003)
Expert Opin Biol Ther
, vol.3
, pp. 1105-1120
-
-
Staton, C.A.1
Brown, N.J.2
Lewis, C.E.3
-
30
-
-
84856013535
-
PPAR-γ agonists, mainly 15d-PGJ(2), reduce eosinophil recruitment following allergen challenge
-
Farnesi-de-Assunção TS, Alves CF, Carregaro V, de OliveiraJR, da Silva CA, et al. (2012) PPAR-γ agonists, mainly 15d-PGJ(2), reduce eosinophil recruitment following allergen challenge. Cell Immunol 273: 23-29.
-
(2012)
Cell Immunol
, vol.273
, pp. 23-29
-
-
Farnesi-de-Assunção, T.S.1
Alves, C.F.2
Carregaro, V.3
de Oliveira, J.R.4
da Silva, C.A.5
-
31
-
-
84855268772
-
Peroxisome Proliferator-Activated Receptor-γ Ligands Alter Breast Cancer Cell Motility through Modulation of the Plasminogen Activator System
-
Carter JC, Church FC, (2011) Peroxisome Proliferator-Activated Receptor-γ Ligands Alter Breast Cancer Cell Motility through Modulation of the Plasminogen Activator System. J Oncol 2011: 594258.
-
(2011)
J Oncol
, vol.2011
, pp. 594258
-
-
Carter, J.C.1
Church, F.C.2
-
32
-
-
79958100824
-
Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration
-
Kaoud TS, Mitra S, Lee S, Taliaferro J, Cantrell M, et al. (2011) Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration. ACS Chem Biol 6: 658-666.
-
(2011)
ACS Chem Biol
, vol.6
, pp. 658-666
-
-
Kaoud, T.S.1
Mitra, S.2
Lee, S.3
Taliaferro, J.4
Cantrell, M.5
-
33
-
-
80052027030
-
JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells
-
Hsu HH, Hu WS, Lin YM, Kuo WW, Chen LM, et al. (2011) JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells. J Biomed Sci 18: 61.
-
(2011)
J Biomed Sci
, vol.18
, pp. 61
-
-
Hsu, H.H.1
Hu, W.S.2
Lin, Y.M.3
Kuo, W.W.4
Chen, L.M.5
-
34
-
-
33644539533
-
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix
-
ten Klooster JP, Jaffer ZM, Chernoff J, Hordijk PL, (2006) Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix. J Cell Biol 172: 759-769.
-
(2006)
J Cell Biol
, vol.172
, pp. 759-769
-
-
ten Klooster, J.P.1
Jaffer, Z.M.2
Chernoff, J.3
Hordijk, P.L.4
-
35
-
-
84863945127
-
β-PIX is critical for transplanted mesenchymal stromal cell migration
-
Koh SH, Huh YM, Noh MY, Kim HY, Kim KS, et al. (2011) β-PIX is critical for transplanted mesenchymal stromal cell migration. Stem Cells Dev; in press.
-
(2011)
Stem Cells Dev; in Press
-
-
Koh, S.H.1
Huh, Y.M.2
Noh, M.Y.3
Kim, H.Y.4
Kim, K.S.5
-
36
-
-
0018761550
-
Dexamethasone stimulation of metallothionein synthesis in HeLa cell cultures
-
Karin M, Herschman HR, (1979) Dexamethasone stimulation of metallothionein synthesis in HeLa cell cultures. Science 204: 176-177.
-
(1979)
Science
, vol.204
, pp. 176-177
-
-
Karin, M.1
Herschman, H.R.2
-
37
-
-
0024441651
-
Metallothionein induction by nonsteroidal antiinflammatory drugs
-
Summer KH, Klein D, de Ruiter N, Abel J, (1989) Metallothionein induction by nonsteroidal antiinflammatory drugs. Biol Trace Elem Res 21: 165-169.
-
(1989)
Biol Trace Elem Res
, vol.21
, pp. 165-169
-
-
Summer, K.H.1
Klein, D.2
de Ruiter, N.3
Abel, J.4
-
38
-
-
79952148728
-
-
Cambridge: RSC Publishing
-
Atrian S, Blindauer CA, Horst Lillig C, Berndt C, Hidalgo J, et al. (2009) Metallothioneins and Related Chelators. Cambridge: RSC Publishing.
-
(2009)
Metallothioneins and Related Chelators
-
-
Atrian, S.1
Blindauer, C.A.2
Horst Lillig, C.3
Berndt, C.4
Hidalgo, J.5
-
39
-
-
0002546264
-
Free radical scavenging actions of metallothionein isoforms I and II
-
Kumari MV, Hiramatsu M, Ebadi M, (1998) Free radical scavenging actions of metallothionein isoforms I and II. Free Radic Res 29: 93-101.
-
(1998)
Free Radic Res
, vol.29
, pp. 93-101
-
-
Kumari, M.V.1
Hiramatsu, M.2
Ebadi, M.3
-
40
-
-
63649149462
-
The role of metallothionein in oncogenesis and cancer prognosis
-
Pedersen MO, Larsen A, Stoltenberg M, Penkowa M, (2009) The role of metallothionein in oncogenesis and cancer prognosis. Prog Histochem Cytochem 44: 29-64.
-
(2009)
Prog Histochem Cytochem
, vol.44
, pp. 29-64
-
-
Pedersen, M.O.1
Larsen, A.2
Stoltenberg, M.3
Penkowa, M.4
-
41
-
-
0036284478
-
Prognostic significance of metallothionein in human gastrointestinal cancer
-
Janssen AM, van Duijn W, Kubben FJ, Griffioen G, Lamers CB, et al. (2002) Prognostic significance of metallothionein in human gastrointestinal cancer. Clin Cancer Res 8: 1889-1896.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1889-1896
-
-
Janssen, A.M.1
van Duijn, W.2
Kubben, F.J.3
Griffioen, G.4
Lamers, C.B.5
-
42
-
-
36049034344
-
Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms
-
Straus DS, Glass CK, (2007) Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Trends Immunol 28: 551-558.
-
(2007)
Trends Immunol
, vol.28
, pp. 551-558
-
-
Straus, D.S.1
Glass, C.K.2
-
43
-
-
63349102350
-
Chemoprevention of colorectal cancer-experimental and clinical aspects
-
Takayama T, Goji T, Taniguchi T, Inoue A, (2009) Chemoprevention of colorectal cancer-experimental and clinical aspects. J Med Invest 56: 1-5.
-
(2009)
J Med Invest
, vol.56
, pp. 1-5
-
-
Takayama, T.1
Goji, T.2
Taniguchi, T.3
Inoue, A.4
|