Nanoscale ZnO induces cytotoxicity and DNA Damage in human cell lines and rat primary neuronal cells

Journal of Nanoscience and Nanotechnology

Volumn 12, Issue 3, 2012, Pages 2126-2135

  Chiang, Hsiu Mei ^a   Xia, Qingsu ^a   Zou, Xiaoju ^a   Wang, Cheng ^a   Wang, Shuguang ^a,b   Miller, Barbara J ^a   Howard, Paul C ^a   Yin, Jun Jie ^c   Beland, Frederick A ^a   Yu, Hongtao ^b   Fu, Peter P ^a,d  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b JACKSON STATE UNIVERSITY   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cytotoxicity; DNA Damage; Reactive Oxygen Species; ZnO Nanoparticles

Indexed keywords

A549 CELLS; CELLULAR GROWTH; DNA DAMAGES; DOSE-DEPENDENT; HEPG2 CELLS; HUMAN CELL LINES; HUMAN FIBROBLAST; HUMAN SKIN; HUMAN SKIN FIBROBLAST; KERATINOCYTES; NANO-ZNO; NANOSCALE ZNO; NEURONAL CELL; REACTIVE OXYGEN SPECIES; TOXIC EFFECT; ZNO NANOPARTICLES;

CELL CULTURE; CELL DEATH; CELL MEMBRANES; DNA; LASER TISSUE INTERACTION; NANOPARTICLES; OXYGEN; RATS; ZINC OXIDE;

CYTOTOXICITY;

CASPASE 3; CASPASE 7; GLUTATHIONE; NANOPARTICLE; ZINC OXIDE;

ANIMAL; ARTICLE; CELL CULTURE; CELL LINE; CELL SURVIVAL; CYTOLOGY; DNA DAMAGE; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; METABOLISM; NERVE CELL; PARTICLE SIZE; RAT; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; CASPASE 3; CASPASE 7; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; DNA DAMAGE; FLUORESCENT ANTIBODY TECHNIQUE; GLUTATHIONE; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NEURONS; PARTICLE SIZE; RATS; ZINC OXIDE;

EID: 84862988627     PISSN: 15334880     EISSN: 15334899     Source Type: Journal    
DOI: 10.1166/jnn.2012.5758     Document Type: Article

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