Sublethal effects of trimethoprim on four freshwater organisms

Ecotoxicology and Environmental Safety

Volumn 82, Issue , 2012, Pages 114-121

  De Liguoro, Marco ^a   Di Leva, Vincenzo ^a   Dalla Bona, Mirco ^a   Merlanti, Roberta ^a   Caporale, Giovanni ^a   Radaelli, Giuseppe ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

D. magna; L. minor; P. reticulata; P. subcapitata; Sublethal toxicity; Trimethoprim

Indexed keywords

CYTOCHROME P450 1A; SURFACE WATER; TRIMETHOPRIM;

ANTIBIOTICS; AQUATIC ORGANISM; AQUATIC PLANT; BIOACCUMULATION; CONCENTRATION (COMPOSITION); CRUSTACEAN; CYPRINID; INHIBITION; MICROALGA; SUBLETHAL EFFECT; SWIMMING BEHAVIOR; TOXICITY;

ALGA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DAPHNIA MAGNA; FRESHWATER FISH; GILL; GROWTH INHIBITION; GUPPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE; KIDNEY; LEMNA MINOR; LOCOMOTION; NONHUMAN; PSEUDOKIRCHNERIELLA SUBCAPITATA; REPRODUCTIVE TOXICITY; TOXICITY TESTING;

ANIMALS; AQUATIC ORGANISMS; ARACEAE; CHLOROPHYTA; DAPHNIA; FRESH WATER; POECILIA; REPRODUCTION; TRIMETHOPRIM; WATER POLLUTANTS, CHEMICAL;

ALGAE; DAPHNIA MAGNA; LEMNA MINOR; POECILIA RETICULATA; SELENASTRUM CAPRICORNUTUM;

EID: 84862982088     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2012.05.016     Document Type: Article

References (42)

1. Andrew J.,.E., Noble C., Kadri S., Jewell H., Huntingford F.,.A. The effect of demand feeding on swimming speed and feeding responses in Atlantic salmon Salmo salar L., gilthead sea bream Sparus aurata L., and European sea bass Dicentrarchus labrax L. in sea cages. Aquacult. Res. 2002, 33:501-507.
2. Binelli A., Parolini M., Cogni D., Pedriali A., Provini A. A multi-biomarker assessment of the impact of the antibacterial trimethoprim on the non-target organism zebra mussel (Dreissena polymorpha). Comp. Biochem. Physiol. C 2009, 150:329-336.
3. Boxall A.B.A., Fogg L.A., Kay P., Blackwell P.A., Pemberton E.J., Croxford A. Prioritisation of veterinary medicines in the UK environment. Toxicol. Lett. 2003, 142:207-218.
4. Brenner C.G.B., Mallmann C.A., Arsand D.R., Mayer F.M., Martins A.F. Determination of sulfamethoxazole and trimethoprim and their metabolites in hospital effluent. Clean - Soil, Air, Water 2011, 39:28-34.
5. CFR US-EPA, 2005. Title 40-Protection of the Environment. PART 797-Environmental Effects Testing Guidelines, Subpart b-Aquatic Guidelines. 797.1050 Algal Acute Toxicity Test.
6. Chemwatch, 2009. Trimethoprim. MSDS no. sc203302 [Online]. CHEMWATCH: Victoria. Australia, Apr 7, 2009. (accessed 22.02.11). http://datasheets.scbt.com/sc-203302.pdf.
7. Cleuvers M. Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects. Toxicol. Lett. 2003, 142:185-194.
8. Dalla Bona, M., Di Leva, V., De Liguoro M., 2011. Effetti di farmaci veterinari sull'attività natatoria di due organismi d'acqua dolce (Effects of veterinary drugs on swimming activity in two freshwater organisms). In: Proceedings of the 65th SISVET National Congress, vol. 65, pp. 141-143.
9. Damsten M.C., de Vlieger J.S., Niessen W.M., Irth H., Vermeulen N.P., Commandeur J.N. Trimethoprim: novel reactive intermediates and bioactivation pathways by cytochrome p450s. Chem. Res. Toxicol. 2008, 21:2181-2187.
10. De Liguoro M., Fioretto B., Poltronieri C., Gallina G. The toxicity of sulfamethazine to D. magna and its additivity to other veterinary sulfonamides and trimethoprim. Chemosphere 2009, 75:1519-1524.
11. Eguchi K., Nagase H., Ozawa M., Endoh Y.S., Goto K., Hirata K., Miyamot K., Yoshimura H. Evaluation of antimicrobial agents for veterinary use in the ecotoxicity test using microalgae. Chemosphere 2004, 57:1733-1738.
12. EMEA, 2005. VICH GL38: Environmental Impact Assessments for Veterinary Medicinal Products-Phase II. European Medicines Agency, London.
13. Environment Canada, 2007. Biological Test Method: Growth Inhibition Test Using a Freshwater Alga. Appendix D: General Procedures for Maintaining Sterile Conditions-Pseudokirchneriella subcapitata. Report EPS 1/RM/25. Environment Canada, Ottawa, 53 pp.
14. Gagné F., Blaise C., André C. Occurrence of pharmaceutical products in a municipal effluent and toxicity to rainbow trout (Onchorhyncus mykiss) hepatocytes. Ecotoxicol. Environ. Saf. 2006, 64:329-336.
15. Halling-Sørensen B., Lützhøft H., Andersen H.R., Ingerslev F. Environmental risk assessment of antibiotics: comparison of mecillinam, trimethoprim and ciprofloxacin. J Antimicrob. Chemother. 2000, 46(Suppl A):53-58.
16. Hektoen H., Berge J.A., Hormazabal V., Yndeslad M. Persistence of antibacterial agents in marine sediments. Aquaculture 1995, 133:175-184.
17. Hu W., Sorrentino C., Denison M.S., Kolaja K., Fielden M.R. Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receztor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro. Mol. Pharmacol. 2007, 71:1475-1486.
18. Jang M.H., Ha K., Takamura N. Reciprocal allelopathic responses between toxic cyanobacteria (Microcystis aeruginosa) and duckweed (Lemna japonica). Toxicon 2007, 49:727-733.
19. Kane A.S., Salierno J.D., Brewer S.K. Fish models in behavioral toxicology: automated techniques, updates and perspectives. Methods in Aquatic Toxicology 2005, Volume 2:559-590. Lewis Publishers, Boca Raton, FL, Chapter 32.
20. Kim Y., Choi K., Jung J., Park S., Kim P., Park J. Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea. Environ. Int. 2007, 33:370-375.
21. Klüttgen B., Dülmer U., Engels M., Ratte H.T. ADaM, an artificial freshwater for the culture of zooplankton. Water Res. 1994, 28:743-746.
22. Klüttgen B., Dülmer U., Engels M., Ratte H.T. Corrigendum. Water Res. 1994, 28(8):1.
23. Kümmerer K. Antibiotics in the aquatic environment - a review - Part I. Chemosphere 2009, 75:417-434.
24. Labonne J., Hendry A.P. Natural and sexual selection giveth and taketh away reproductive barriers: models of population divergence in guppies. Am. Nat. 2010, 176:26-39.
25. Landis W.G., Sofield R.M., Yu M.-H. Introduction to Environmental Toxicology: Molecular Substructures to Ecological Landscapes 2011, Boca Raton (FL): Lewis/CRC, 524 p. 4th ed.
26. Le T.X., Munekage Y. Residues of selected antibiotics in water and mud from shrimp ponds in mangrove areas in Viet Nam. Mar. Pollut. Bull. 2004, 49:922-929.
27. Lindberg R., Wennberg P., Johansson M., Tysklind M., Andersson B. Screening of human antibiotic substances and determination of weekly mass flows in five sewage treatment plants in Sweden. Environ. Sci. Technol. 2005, 39:3421-3429.
28. Lochmatter, T., Roduit, P., Cianci, C., Correll, N., Jacot, J., Martinoli, A., 2008. SwisTrack-a flexible open source tracking software for multi-agent systems. In: Proceedings of the 2008 IEEE/RSJ International Conference on Intelligent Robots and Systems, pp. 4004-4010.
29. Nichols H.W. Growth media-freshwater. Handbook of Phycological Methods 1973, 7-24. Cambridge University Press, Cambridge. J.R. Stein (Ed.).
30. OECD OECD Guidelines for the Testing of Chemicals. Guideline 204: Fish, Prolonged Toxicity Test 1984, Organization for Economic Co-operation and Development, Paris.
31. OECD OECD Guidelines for the Testing of Chemicals. Guideline 203: Fish, Acute Toxicity Test 1992, Organization for Economic Co-operation and Development, Paris.
32. OECD OECD Guidelines for the Testing of Chemicals. Guideline 211: Daphnia magna Reproduction Test 1998, Organization for Economic Co-operation and Development, Paris.
33. OECD OECD Guidelines for the Testing of Chemicals. Guideline 221: Lemna sp., Growth Inhibition Test 2006, Organization for Economic Co-operation and Development, Paris.
34. Ortiz-Delgado J.B., Segner H., Sarasquete C. Cellular distribution and induction of CYP1A following exposure of gilthead seabream, Sparus aurata, to waterborne and dietary benzo(a)pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin: An immunohistochemical approach. Aquat. Toxicol. 2005, 75:144-161.
35. Park S., Choi K. Hazard assessment of commonly used agricultural antibiotics on aquatic ecosystems. Ecotoxicology 2008, 17:526-538.
36. Saidinejad M., Ewald M.B., Shannon M.W. Transient psychosis in an immune-competent patient after oral trimethoprim-sulfamethoxazole administration. Pediatrics 2005, 115:739-741.
37. Santos L.H., Araújo A.N., Fachini A., Pena A., Delerue-Matos C., Montenegro M.C. Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment. J. Hazard. Mater. 2010, 175:45-95.
38. Sarasquete C., Segner H. Cytochrome P4501A (CYP1A) in teleostean fishes. A review of immunohistological studies. Sci. Total Environ. 2000, 247:313-332.
39. Stack A., Schott H.C.2nd Suspect novel adverse drug reactions to trimethoprim-sulphonamide combinations in horses: a case series. Equine Vet. J 2011, 43:117-120.
40. Stegeman J.J., Hahn M.E. Biochemistry and molecular biology of monooxygenases: current perspective on forms, functions, and regulation of cytochrome P450 in aquatic species. Aquatic Toxicology 1994, 87-203. D.C. Malins, G.K. Ostrander (Eds.).
41. von der Ohe P.C., Dulio V., Slobodnik J., De Deckere E., Kühne R., Ebert R.U., Ginebreda A., DeCooman W., Schüürmann G., Brack W. A new risk assessment approach for the prioritization of 500 classical and emerging organic microcontaminants as potential river basin specific pollutants under the European Water Framework Directive. Sci. Total Environ. 2011, 409:2064-2077.
42. Weston D.P. Environmental considerations in the use of antibacterial drugs in aquaculture. Aquaculture and Water Resources Management 1996, 140-165. Blackwell Science. D. Baird, M. Beveridge, L. Kelly, J. Muir (Eds.).