Optical control of focal epilepsy in vivo with caged γ-aminobutyric acid

Annals of Neurology

Volumn 71, Issue 1, 2012, Pages 68-75

  Yang, Xiaofeng ^a   Rode, Daniel L ^b   Peterka, Darcy S ^c   Yuste, Rafael ^c   Rothman, Steven M ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID DERIVATIVE; 4 AMINOPYRIDINE; ANTICONVULSIVE AGENT; PICROTOXIN; RUTHENIUM BIPYRIDINE TRIPHENYLPHOSPHINE 4 AMINOBUTYRIC ACID; RUTHENIUM DERIVATIVE; TRIPHENYLPHOSPHINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BLUE LIGHT; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE DURATION; DRUG EFFICACY; DRUG RECEPTOR BINDING; FOCAL EPILEPSY; ILLUMINATION; IN VIVO STUDY; LIGHT EMITTING DIODE; MALE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; RAT; SPIKE WAVE;

ACTION POTENTIALS; ANIMALS; DRUG CARRIERS; EPILEPSIES, PARTIAL; GAMMA-AMINOBUTYRIC ACID; MALE; NEOCORTEX; ORGAN CULTURE TECHNIQUES; PHOTIC STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; RUTHENIUM;

EID: 84862946927     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.22596     Document Type: Article

References (24)

1. Sander, J,. The natural history of epilepsy in the era of new antiepileptic drugs and surgical treatment. Epilepsia 2003; 44 (suppl 1): 17-20. (Pubitemid 36206002)
2. Tellez-Zenteno J, Dhar R, Hernandez-Ronquillo L, et al. Long-term outcomes in epilepsy surgery: antiepileptic drugs, mortality, cognitive and psychosocial aspects. Brain 2007; 130: 334-345. (Pubitemid 46181088)
3. Spencer S, Huh L,. Outcomes of epilepsy surgery in adults and children. Lancet Neurol 2008; 7: 525-537. (Pubitemid 351657493)
4. Fisher R, Salanova V, Witt T, et al. Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy. Epilepsia 2010; 51: 899-908.
5. Eder H, Jones D, Fisher R,. Local perfusion of diazepam attenuates interictal and ictal events in the bicuculline model of epilepsy in rats. Epilepsia 1997; 38: 516-521. (Pubitemid 27199904)
6. Yang X-F, Rothman S,. Focal cooling rapidly terminates experimental neocortical seizures. Ann Neurol 2001; 49: 721-726. (Pubitemid 32530238)
7. Nakken K, Henriksen O, Roste G, et al. Vagal nerve stimulationâthe Norwegian experience. Seizure 2003; 12: 37-41. (Pubitemid 36113761)
8. Tonnesen J, Sorensen A, Deisseroth K, et al. Optogenetic control of epileptiform activity. Proc Natl Acad Sci U S A 2009; 106: 12162-12167.
9. Rothman S, Perry G, Yang X, et al. Optical suppression of seizure-like activity with an LED. Epilepsy Res 2007; 74: 201-209. (Pubitemid 46654750)
10. Yang X, Schmidt B, Rode D, et al. Optical suppression of experimental seizures in rat brain slices. Epilepsia 2010; 51: 127-135.
11. Rial Verde E, Zayat L, Etchenique R, et al. Photorelease of GABA with visible light using an inorganic caging group. Front Neural Circuits 2008; 2: 2.
12. Hill M, Wong M, Amarakone A, et al. Rapid cooling aborts seizure-like activity in rodent hippocampal-entorhinal slices. Epilepsia 2000; 41: 1241-1248.
13. Kapur J, Macdonald R,. Rapid seizure-induced reduction of benzodiazepine and Zn2+ sensitivity of hippocampal dentate granule cell GABA(A) receptors. J Neurosci 1997; 17: 7532-7540. (Pubitemid 27413283)
14. Uva L, Avoli M, de Curtis M,. Synchronous GABA-receptor-dependent potentials in limbic areas of the in-vitro isolated adult guinea pig brain. Eur J Neurosci 2009; 29: 911-920.
15. John J, Baptiste S, Sheffield L, et al. Transmeningeal delivery of GABA to control neocortical seizures in rats. Epilepsy Res 2007; 75: 10-17. (Pubitemid 46856114)
16. Ludvig N, Baptiste S, Tang H, et al. Localized transmeningeal muscimol prevents neocortical seizures in rats and nonhuman primates: therapeutic implications. Epilepsia 2009; 50: 678-693.
17. Eisenman L, Shu H, Akk G, et al. Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light. Nat Neurosci 2007; 10: 523-530. (Pubitemid 46494583)
18. Fortin D, Banghart M, Dunn T, et al. Photochemical control of endogenous ion channels and cellular excitability. Nat Methods 2008; 5: 331-338. (Pubitemid 351455160)
19. Eisenman L, Shu H, Wang C, et al. NMDA potentiation by visible light in the presence of a fluorescent neurosteroid analogue. J Physiol 2009; 587: 2937-2947.
20. Scimemi A, Semyanov A, Sperk, G, et al. Multiple and plastic receptors mediate tonic GABAA receptor currents in the hippocampus. J Neurosci 2005; 25: 10016-10024. (Pubitemid 41528040)
21. Farrant M, Nusser Z,. Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors. Nat Rev Neurosci 2005; 6: 215-229. (Pubitemid 40342416)
22. Albright A, Turner M, Pattisapu J,. Best-practice surgical techniques for intrathecal baclofen therapy. J Neurosurg 2006; 104: 233-239. (Pubitemid 44968421)
23. Morrell M,. Brain stimulation for epilepsy: can scheduled or responsive neurostimulation stop seizures? Curr Opin Neurol 2006; 19: 164-168.
24. Schubert E, and, Kim J,. Solid-state light sources getting smart. Science 2005; 308: 1274-1278. (Pubitemid 40746117)