Effect of insulin by local injection on the level of systemic blood glucose and granulation tissue formation of wound in patients with diabetic foot ulcer

Chinese Journal of Burns

Volumn 27, Issue 6, 2011, Pages 451-455

  Zhang, Zhao Xin ^a   Liu, Xiao Long ^a   Lü, Lei ^a   Zhang, Liang ^a   Ji, Dong Liang ^a   Liu, Li Hua ^a  

^a PEOPLE S HOSPITAL OF XINJIANG UYGUR AUTONOMOUS REGION   (China)

Author keywords

Blood glucose; Diabetic foot; Insulin; Wound healing

Indexed keywords

CD34 ANTIGEN; GLUCOSE; INSULIN; SODIUM CHLORIDE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEBRIDEMENT; DIABETES MELLITUS; DIABETIC FOOT; DIET RESTRICTION; GLUCOSE BLOOD LEVEL; GRANULATION TISSUE; HOSPITALIZATION; HUMAN; HUMAN TISSUE; MICROVASCULATURE;

ADULT; AGED; AGED, 80 AND OVER; BLOOD GLUCOSE; DIABETIC FOOT; FEMALE; HUMANS; INJECTIONS; INSULIN; MALE; MIDDLE AGED; WOUND HEALING;

EID: 84862943440     PISSN: 10092587     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.1009-2587.2011.06.014     Document Type: Article

References (17)

1. American Diabetes Association. Standards of medical care in diabetes - 2010. Diabetes Care, 2010, 33 Suppl 1:S11-61.
2. Pareek G, Shevchuk M, Armenakas NA, et al. The effect of finasteride on the expression of vascular endothelial growth factor and microvessel density: a possible mechanism for decreased prostatic bleeding in treated patients. J Urol, 2003,169(1):20-23. (Pubitemid 35461539)
3. Dandona P, Mohanty P, Chaudhuri A, et al. Insulin infusion in acute illness. J Clin Invest, 2005,115(8):2069-2072. (Pubitemid 41134145)
4. Langouche L, Vanhorebeek I, Vlasselaers D, et al. Intensive insulin therapy protects the endothelium of critically ill patients. J Clin Invest, 2005,115(8):2277-2286. (Pubitemid 41134169)
5. Schramm JC, Dinh T, Veves A. Microvascular changes in the diabetic foot. Int J Low Extrem Wounds, 2006,5(3):149-159. (Pubitemid 44215096)
6. Martin A, Komada MR, Sane DC. Abnormal angiogenesis in diabetes mellitus. Med Res Rev, 2003,23(2):117-145. (Pubitemid 36241095)
7. Cho CH, Sung HK, Kim KT, et al. COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model. Proc Natl Acad Sci U S A, 2006,103(13):4946-4951.
8. Zhang XJ, Chinkes DL, Sadagopa Ramanujam VM, et al. Local injection of insulin-zinc stimulates DNA synthesis in skin donor site wound. Wound Repair Regen, 2007,15(2):258-265. (Pubitemid 46376388)
9. Zhang XJ, Wu X, Wolf SE, et al. Local insulin-zinc injection accelerates skin donor site wound healing. J Surg Res, 2007,142
10. Velander P, Theopold C, Hirsch T, et al. Impaired wound healing in an acute diabetic pig model and the effects of local hyperglycemia. Wound Repair Regen, 2008,16(2):288-293. (Pubitemid 351342136)