Salvianic acid A inhibits lipopolysaccharide-induced apoptosis through regulating glutathione peroxidase activity and malondialdehyde level in vascular endothelial cells

Chinese Journal of Natural Medicines

Volumn 10, Issue 1, 2012, Pages 53-57

  Zhao, Qi Tao ^a   Guo, Qing Mei ^a   Wang, Peng ^a   Wang, Qian ^a  

^a SHANDONG UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Glutathione peroxidase; Lipopolysaccharide; Malondialdehyde; Salvianic acid A; Vascular endothelial cells

Indexed keywords

GLUTATHIONE PEROXIDASE; LIPOPOLYSACCHARIDE; MALONALDEHYDE; NATURAL PRODUCT; PROPIDIUM IODIDE; SALVIANIC ACID A; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL NUCLEUS; CELL STRUCTURE; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PHASE CONTRAST MICROSCOPE; SPECTROPHOTOMETRY; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM;

EID: 84862941873     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(12)60012-0     Document Type: Article

References (19)

1. Ren ZH, Tong YH, Xu W, et al. Tanshinone II A attenuates inflammatory responses of rats with myocardial infarction by reducing MCP-1 expression [J]. Phytomedicine 2010, 17(3-4):212-218.
2. Fan GW, Gao XM, Wang H, et al. The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS [J]. Steroid Biochem Mol Biol 2009, 113(3-5):275-280.
3. Wang CY, Ma FL, Liu JT, et al. Protective effect of salvianic acid A on acute liver injury induced by carbon tetrachloride in rats [J]. Biol Pharm Bull 2007, 30(1):44-47.
4. Namisaki T, Yoshiji H, Noguchi R, et al. The vascular endothelial growth factor (VEGF) receptor-2 is a major regulator of VEGF-mediated salvage effect in murine acute hepatic failure [J]. Angiogenes Res 2010, 24(2):16-24.
5. Zha RP, Xu W, Wang WY, et al. Prevention of lipopolysaccharide-induced injury by 3, 5-dicaffeoylquinic acid in endothelial cells [J]. Acta Pharmacol Sin 2007, 28(8):1143-1148.
6. Wang XJ, Wang ZB, Xu JX Effect of salvianic acid A on lipid peroxidation and membrane permeability in mitochondria [J]. J Ethnopharmacol 2005, 97(3):441-445.
7. Jaffe EA, Nachman RL, Becker CG Culture of human endothelial cells derived from umbilical veins [J]. J Clin Invest 1973, 52(11):2745-2756.
8. Du A, Zhao B, Miao J, et al. Safrole oxide induces apoptosis by up-regulating Fas and FasL instead of integrin beta4 in A549 human lung cancer cells [J]. Bioorg Med Chem 2006, 4(7):2438-2445.
9. Li MH, Chen JM, Peng Y, et al. Investigation of Danshen and related medicinal plants in China [J]. Ethnopharmacol 2008, 120(3):419-426.
10. Park S, Kim JA, Choi S, et al. Superoxide is a potential culprit of caspase-3 dependent endothelial cell death induced by lysophosphatidylcholine [J]. Physiol Pharmacol 2010, 61(4):375-381.
11. Maceneaney OJ, Desouza CA, Weil BR, et al. Prehypertension and endothelial progenitor cell function [J]. Hum Hypertens 2010, 25(1):57-62.
12. Ferrari R, Guardigli G, Ceconi C Secondary Prevention of CAD with ACE Inhibitors: A Struggle Between Life and Death of the Endothelium [J]. Cardiovasc Drugs Ther 2010, 24(4):331-339.
13. Pohlman TH, Harlan JM Adaptive responses of the endothelium to stress [J]. Surg Res 2000, 89(1):85-119.
14. Chandra J, Samali A, Orrenius S Triggering and modulation of apoptosis by oxidative stress [J]. Free Radic Biol Med 2000, 29(3-4):323-333.
15. Kotamraju S, Chitambar CR, Kalivendi SV, et al. Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial cells: role of oxidant-induced iron signaling in apoptosis [J]. Biol Chem 2002, 277(19):17179-17187.
16. Slemmer JE, Shacka JJ, Sweeney MI, Weber JT Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging [J]. Curr Med Chem 2008, 15(4):404-414.
17. Du CQ, Zhao QT, Araki S, et al. Apoptosis mediated by phosphatidylcholine-specific phospholipase C is associated with cAMP, P53 level, and cell-cycle distribution in vascular endothelial cells [J]. Endothelium 2003, 10(3):141-147. 2003.
18. Liu X, Zhao Q, Araki S, et al. Contrasting effects of phosphatidylinositol- and phosphatidylcholine-specific phospholipase C on apoptosis in cultured endothelial cells [J]. Endothelium 2006, 13(3):205-211.
19. Zhang N, Ahsan MH, Zhu L, et al. 2005. NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation [J]. Biol Chem 2005, 280(22):21400-21408.