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Volumn 122, Issue 2, 2012, Pages 74-81

Melanocortin 4 receptor induces hyperalgesia and allodynia after chronic constriction injury by activation of p38 MAPK in DRG

Author keywords

CCI; HS014; neuropathic pain; P38MAPK

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA INTERMEDIN[11-22][11 (N ACETYLCYSTEINE) 14 [3 (2 NAPHTHYL) DEXTRO ALANINE] 18 CYSTEINE 22 ASPARTIC ACID AMIDE] 11,18 CYCLIC DISULFIDE; MELANOCORTIN 4 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 84862938884     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.3109/00207454.2011.630542     Document Type: Article
Times cited : (23)

References (21)
  • 1
    • 0346655315 scopus 로고    scopus 로고
    • Activation of p38 Mitogen-Activated Protein Kinase in Spinal Hyperactive Microglia Contributes to Pain Hypersensitivity Following Peripheral Nerve Injury
    • DOI 10.1002/glia.10308
    • Tsuda M, Mizokoshi A, Shigemoto-Mogami Y, Koizumi S, Inoue K. Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury. Glia. 2004;45:89-95. (Pubitemid 38076231)
    • (2004) GLIA , vol.45 , Issue.1 , pp. 89-95
    • Tsuda, M.1    Mizokoshi, A.2    Shigemoto-Mogami, Y.3    Koizumi, S.4    Inoue, K.5
  • 2
    • 58749098812 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia
    • Wen YR, SuterMR, Ji RR, Yeh GC,Wu YS,Wang KC, Kohno T, SunWZ,Wang CC. Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia. Anesthesiology. 2009;110:155-65.
    • (2009) Anesthesiology , vol.110 , pp. 155-165
    • Wen, Y.R.1    Suter, M.R.2    Ji, R.R.3    Yeh, G.C.4    Wu, Y.S.5    Wang, K.C.6    Kohno, T.7    Sun, W.Z.8    Wang, C.C.9
  • 3
    • 0037147689 scopus 로고    scopus 로고
    • Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury
    • Kim SY, Bae JC, Kim JY, Lee HL, Lee KM, Kim DS, Cho HJ. Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury. Neuroreport. 2002;13:2483-6.
    • (2002) Neuroreport , vol.13 , pp. 2483-2486
    • Kim, S.Y.1    Bae, J.C.2    Kim, J.Y.3    Lee, H.L.4    Lee, K.M.5    Kim, D.S.6    Cho, H.J.7
  • 4
    • 0037705314 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain
    • Jin SX, Zhuang ZY, Woolf CJ, Ji RR. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J Neurosci. 2003;23:4017-22. (Pubitemid 36958419)
    • (2003) Journal of Neuroscience , vol.23 , Issue.10 , pp. 4017-4022
    • Jin, S.-X.1    Zhuang, Z.-Y.2    Woolf, C.J.3    Ji, R.-R.4
  • 5
    • 8544239374 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation
    • DOI 10.1523/JNEUROSCI.3388-04.2004
    • Obata K, Yamanaka H, Kobayashi K, Dai Y, Mizushima T, Katsura H, Fukuoka T, Tokunaga A, Noguchi K. Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation. J Neurosci. 2004;24:10211-22. (Pubitemid 39492048)
    • (2004) Journal of Neuroscience , vol.24 , Issue.45 , pp. 10211-10222
    • Obata, K.1    Yamanaka, H.2    Kobayashi, K.3    Dai, Y.4    Mizushima, T.5    Katsura, H.6    Fukuoka, T.7    Tokunaga, A.8    Noguchi, K.9
  • 6
    • 76049089494 scopus 로고    scopus 로고
    • Peripheral antinociceptive effects of MC4 receptor antagonists in a rat model of neuropathic pain-A biochemical and behavioral study
    • Starowicz K, Mousa SA, Obara I, Chocyk A, Przewłocki R, Wedzony K, Machelska H, Przewłocka B. Peripheral antinociceptive effects of MC4 receptor antagonists in a rat model of neuropathic pain - a biochemical and behavioral study. Pharmacol Rep. 2009;61:1086-95.
    • (2009) Pharmacol. Rep. , vol.61 , pp. 1086-1095
    • Starowicz, K.1    Mousa, S.A.2    Obara, I.3    Chocyk, A.4    Przewłocki, R.5    Wedzony, K.6    Machelska, H.7    Przewłocka, B.8
  • 7
    • 1542404590 scopus 로고    scopus 로고
    • Melanocortin 4 receptor is expressed in the dorsal root ganglions and down-regulated in neuropathic rats
    • DOI 10.1016/j.neulet.2003.12.096, PII S0304394004000217
    • Starowicz K, Bilecki W, Sieja A, Przewlocka B, Przewlocki R. Melanocortin 4 receptor is expressed in the dorsal root ganglions and down-regulated in neuropathic rats. Neurosci Lett. 2004;358:79-82. (Pubitemid 38340725)
    • (2004) Neuroscience Letters , vol.358 , Issue.2 , pp. 79-82
    • Starowicz, K.1    Bilecki, W.2    Sieja, A.3    Przewlocka, B.4    Przewlocki, R.5
  • 8
    • 0023895875 scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • Bennett GJ, Xie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain. 1988;33:87-107.
    • (1988) Pain. , vol.33 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.K.2
  • 9
    • 0017036162 scopus 로고
    • Chronic catheterization of the spinal subarachnoid space
    • DOI 10.1016/0031-9384(76)90029-9
    • Yaksh TL, Rudy TA. Chronic catheterization of the spinal subarachnoid space. Physiol Behav. 1976;17:1031-6. (Pubitemid 8063691)
    • (1976) Physiology and Behavior , vol.17 , Issue.6 , pp. 1031-1036
    • Yaksh, T.L.1    Rudy, T.A.2
  • 10
    • 77955409173 scopus 로고    scopus 로고
    • The melanocortin-4 receptor: Physiology pharmacology and pathophysiology
    • Tao Y-X. The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology. Endocrine Rev. 2010;31(4):506-43.
    • (2010) Endocrine. Rev. , vol.31 , Issue.4 , pp. 506-543
    • Tao, Y.X.1
  • 11
    • 33846311331 scopus 로고    scopus 로고
    • Identification of differential melanocortin 4 receptor agonist profiles at natively expressed receptors in rat cortical astrocytes and recombinantly expressed receptors in human embryonic kidney cells
    • DOI 10.1016/j.neuropharm.2006.08.015, PII S0028390806002863
    • Selkirk JV, Nottebaum LM, Lee J, Yang W, Foster AC, Lechner SM. Identification of differentialmelanocortin 4 receptor agonist profiles at natively expressed receptors in rat cortical astrocytes and recombinantly expressed receptors in human embryonic kidney cells. Neuropharmacology. 2007;52:459-66. (Pubitemid 46123362)
    • (2007) Neuropharmacology , vol.52 , Issue.2 , pp. 459-466
    • Selkirk, J.V.1    Nottebaum, L.M.2    Lee, J.3    Yang, W.4    Foster, A.C.5    Lechner, S.M.6
  • 12
    • 34748907751 scopus 로고    scopus 로고
    • Activation of melanocortin 4 receptors reduces the inflammatory response and prevents apoptosis induced by lipopolysaccharide and interferon-γ in astrocytes
    • DOI 10.1210/en.2007-0366
    • Caruso C, Durand D, Schiöth HB, Rey R, Seilicovich A, Lasaga M. Activation of melanocortin 4 receptors reduces the inflammatory response and prevents apoptosis induced by lipopolysaccharide and interferon-γ in astrocytes. Endocrinology. 2007;148:4918-26. (Pubitemid 47481532)
    • (2007) Endocrinology , vol.148 , Issue.10 , pp. 4918-4926
    • Caruso, C.1    Durand, D.2    Schioth, H.B.3    Rey, R.4    Seilicovich, A.5    Lasaga, M.6
  • 13
    • 11144324509 scopus 로고    scopus 로고
    • Endogenous and exogenous melanocortin antagonists induce anti-allodynic effects in a model of rat neuropathic pain
    • DOI 10.1016/j.bbr.2004.06.008, PII S0166432804002384
    • Bertorelli R, Fredduzzi S, Tarozzo G, Campanella M, Grundy R, Beltramo M, Reggiani A. Endogenous and exogenous melanocortin antagonists induce antiallodynic effects in amodel of rat neuropathic pain. Behav Brain Res. 2005;157:55-62. (Pubitemid 40029699)
    • (2005) Behavioural Brain Research , vol.157 , Issue.1 , pp. 55-62
    • Bertorelli, R.1    Fredduzzi, S.2    Tarozzo, G.3    Campanella, M.4    Grundy, R.5    Beltramo, M.6    Reggiani, A.7
  • 14
    • 0345701254 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons
    • Schafers M, Svensson CI, Sommer C, Sorkin LS. Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons. J Neurosci. 2003;23:2517-21. (Pubitemid 36418584)
    • (2003) Journal of Neuroscience , vol.23 , Issue.7 , pp. 2517-2521
    • Schafers, M.1    Svensson, C.I.2    Sommer, C.3    Sorkin, L.S.4
  • 15
    • 36549088168 scopus 로고    scopus 로고
    • The influence of p38 mitogen-activated protein kinase inhibitor on synthesis of inflammatory cytokine tumor necrosis factor alpha in spinal cord of rats with chronic constriction injury
    • DOI 10.1213/01.ane.0000287660.29297.7b, PII 0000053920071200000051
    • Xu L, Huang YG, Yu X, Yue J, Yang N, Zuo P. The influence of p38 mitogen-activated protein kinase inhibitor on synthesis of inflammatory cytokine tumor necrosis factor alpha in spinal cord of rats with chronic constriction injury. Int Anesth Res Soc. 2007;105(6):1838-44. (Pubitemid 350190586)
    • (2007) Anesthesia and Analgesia , vol.105 , Issue.6 , pp. 1838-1844
    • Xu, L.1    Huang, Y.2    Yu, X.3    Yue, J.4    Yang, N.5    Zuo, P.6
  • 16
    • 33745246073 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase in spinal cord contributes to chronic constriction injury-induced neuropathic pain
    • Zhang FE, Cao JL, Zhang LC, Zeng YM. Activation of p38 mitogen-activated protein kinase in spinal cord contributes to chronic constriction injury-induced neuropathic pain. Acta Physiol Sinica. 2005;57(5):545-51.
    • (2005) Acta. Physiol. Sinica. , vol.57 , Issue.5 , pp. 545-551
    • Zhang, F.E.1    Cao, J.L.2    Zhang, L.C.3    Zeng, Y.M.4
  • 17
    • 77955560673 scopus 로고    scopus 로고
    • Interleukin-6 induces microglial CX3CR1 expression in the spinal cord after peripheral nerve injury through the activation of p38 MAPK
    • Lee KM, Jeon SM, Cho HJ. Interleukin-6 induces microglial CX3CR1 expression in the spinal cord after peripheral nerve injury through the activation of p38 MAPK. Eur J Pain. 2010;14:682e1-e12.
    • (2010) Eur. J. Pain. , vol.14
    • Lee, K.M.1    Jeon, S.M.2    Cho, H.J.3
  • 18
    • 33750042605 scopus 로고    scopus 로고
    • Melanocortin-4 receptor-mediated inhibition of apoptosis in immortalized hypothalamic neurons via mitogen-activated protein kinase
    • DOI 10.1016/j.peptides.2006.05.005, PII S0196978106002403
    • Chai B, Li J-Y, Zhang W, Newman E, Ammori J, Mulholland MW. Melanocortin-4 receptor-mediated inhibition of apoptosis in immortalized hypothalamic neurons via mitogen-activated protein kinase. Peptides. 2006;27:2846-57. (Pubitemid 44584391)
    • (2006) Peptides , vol.27 , Issue.11 , pp. 2846-2857
    • Chai, B.1    Li, J.-Y.2    Zhang, W.3    Newman, E.4    Ammori, J.5    Mulholland, M.W.6
  • 19
    • 35948948698 scopus 로고    scopus 로고
    • Central administration of selective melanocortin 4 receptor antagonist HS014 prevents morphine tolerance and withdrawal hyperalgesia
    • DOI 10.1016/j.brainres.2007.08.054, PII S0006899307019968
    • Kalange AS, Kokare DM, Singru PS, Upadhya MA, Chopde CT, Subhedar NK. Central administration of selective melanocortin 4 receptor antagonist HS014 prevents morphine tolerance and withdrawal hyperalgesia. J Brain Res. 2007;1181:10-20. (Pubitemid 350064270)
    • (2007) Brain Research , vol.1181 , Issue.1 , pp. 10-20
    • Kalange, A.S.1    Kokare, D.M.2    Singru, P.S.3    Upadhya, M.A.4    Chopde, C.T.5    Subhedar, N.K.6
  • 20
    • 84862946478 scopus 로고    scopus 로고
    • Role of melanocortin receptor 4 in excitatory amino acid release from rat astrocytes in spinal cord
    • Chu HC, Luo YJ, Sun XP, Yin JH. Role of melanocortin receptor 4 in excitatory amino acid release from rat astrocytes in spinal cord. Chinese J Anesthesiol. 2010;30(5):569-71.
    • (2010) Chinese J. Anesthesiol. , vol.30 , Issue.5 , pp. 569-571
    • Chu, H.C.1    Luo, Y.J.2    Sun, X.P.3    Yin, J.H.4
  • 21
    • 34249717859 scopus 로고    scopus 로고
    • Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine
    • DOI 10.1016/j.bbi.2006.11.003, PII S0889159106003540, Neuropathic Pain, Glia and Cytokines
    • Zhuang ZY, Kawasaki Y, Tan PH, Wen YR, Huang J, Ji RR. Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav Immun. 2007;21:642-51. (Pubitemid 46830963)
    • (2007) Brain, Behavior, and Immunity , vol.21 , Issue.5 , pp. 642-651
    • Zhuang, Z.-Y.1    Kawasaki, Y.2    Tan, P.-H.3    Wen, Y.-R.4    Huang, J.5    Ji, R.-R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.