Cu/Zn- and Mn-superoxide dismutases are specifically up-regulated in neurons after focal brain injury

Journal of Neurobiology

Volumn 45, Issue 1, 2000, Pages 39-46

  Takeuchi, Akihide ^a,b   Miyaishi, Osamu ^a   Kiuchi, Kazutoshi ^b,c   Isobe, Ken Ichi ^a,b  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b RIKEN   (Japan)

^c GIFU UNIVERSITY   (Japan)

Author keywords

C6 cells; Free radicals; Neuronal damage; PC12 cells; Superoxide dismutase

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CELL DEATH; ENZYME REGULATION; GLIA CELL; MICROGLIA; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; BRAIN INJURIES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CORPUS STRIATUM; ENZYME INDUCTION; ETHANOL; GLIOMA; NEUROGLIA; NEURONS; NITRIC OXIDE DONORS; PC12 CELLS; PENICILLAMINE; RATS; SUPEROXIDE DISMUTASE; UP-REGULATION;

EID: 0033803464     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4695(200010)45:1<39::AID-NEU4>3.0.CO;2-A     Document Type: Article

References (29)

1. Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism
2. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
3. Extracellular superoxide dismutase is upregulated with inducible nitric oxide synthase after NF-kappa B activation
4. Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase
5. Modulation of endogenous antioxidant enzymes by nitric oxide in rat C6 glial cells
6. Free radicals as mediators of neuronal injury
7. Identification of copper/zinc superoxide dismutase as a novel nitric oxide-regulated gene in rat glomerular mesangial cells and kidneys of endotoxemic rats
8. Superoxide dismutases. An adaptation to a paramagnetic gas
9. Phorbol ester induces manganese-superoxide dismutase in tumor necrosis factor-resistant cells
10. Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: Molecular mechanisms of neuronal death and protection
11. Manganese superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity
12. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
13. Regulation of the manganese superoxide dismutase and inducible nitric oxide synthase gene in rat neuronal and glial cells
14. Reduction of Cu/Zn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia
15. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
16. Human disease, free radicals, and the oxidant/antioxidant balance
17. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
18. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
19. A nitric oxide-releasing reagent, S-nitroso-N-acetylpenicillamine, enhances the expression of superoxide dismutases mRNA in the murine macrophage cell line RAW264-7
20. Mitochondrial dysfunction is a primary event in glutamate neurotoxicity
21. Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension
22. Widespread peroxynitrite-mediated damage in Alzheimer's disease
23. Induction of manganese superoxide dismutase in BV-2 microglial cells
24. Microglial NO induces delayed neuronal death following acute injury in the striatum
25. Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway
26. Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells
27. Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
28. The oxidative inactivation of mitochondrial electron transport chain components and ATPase