Pyridoxine inhibits endothelial NOS uncoupling induced by oxidized low-density lipoprotein via the PKCα signalling pathway in human umbilical vein endothelial cells

British Journal of Pharmacology

Volumn 165, Issue 3, 2012, Pages 754-764

  Xie, Liping ^a   Liu, Zhen ^a   Lu, Hui ^a   Zhang, Wen ^a   Mi, Qiongyu ^a   Li, Xiaozhen ^a   Tang, Yan ^a   Chen, Qi ^a   Ferro, Albert ^b   Ji, Yong ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

eNOS uncoupling; oxidized low density lipoprotein (ox LDL); protein kinase C; pyridoxine

Indexed keywords

APOCYNIN; CHELERYTHRINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROETHIDINE; LUCIGENIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; OXIDIZED LOW DENSITY LIPOPROTEIN; OXYGEN; PROTEIN KINASE C ALPHA; PROTEIN P47; PYRIDOXINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; THREONINE;

ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; CYTOSOL; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPROTEINS, LDL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; PYRIDOXINE; SIGNAL TRANSDUCTION; SUPEROXIDES; VITAMIN B COMPLEX;

EID: 84862909988     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01607.x     Document Type: Article

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