Jarid2 (Jumonji, AT rich interactive domain 2) regulates NOTCH1 expression via histone modification in the developing heart

Journal of Biological Chemistry

Volumn 287, Issue 2, 2012, Pages 1235-1241

  Mysliwiec, Matthew R ^a   Carlson, Clayton D ^a   Tietjen, Josh ^a   Hung, Holly ^a   Ansari, Aseem Z ^a   Lee, Youngsook ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROCESS; CHIP-CHIP; CO-IMMUNOPRECIPITATION EXPERIMENTS; EPIGENETIC REGULATION; GENOMIC LOCUS; H3K9 METHYLATION; HEART DEVELOPMENT; HISTONE H3; HISTONE MODIFICATION; INTERACTIVE DOMAINS; KNOCK OUTS; LYSINE-9; METHYLTRANSFERASES; MOLECULAR BASIS; ORGAN DEVELOPMENT; PHYSICAL INTERACTIONS; PUTATIVE COFACTOR; SPECIFIC INTERACTION; TARGET GENES; TRANSCRIPTIONAL REPRESSORS; YEAST TWO HYBRID;

ALKYLATION; AMINO ACIDS; BIOLOGICAL ORGANS; GENES; MAMMALS; METHYLATION; PROTEINS;

HEART;

HISTONE; HISTONE METHYLTRANSFERASE; LYSINE; NOTCH1 RECEPTOR; RETINOBLASTOMA BINDING PROTEIN 2; SETDB1 ENZYME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME LOCALIZATION; EPIGENETICS; FEMALE; GENE; GENE CONTROL; GENE DELETION; GENE EXPRESSION REGULATION; GENE LOCUS; GENE TARGETING; GENETIC ASSOCIATION; HEART DEVELOPMENT; HISTONE METHYLATION; HISTONE MODIFICATION; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NOTCH1 GENE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION;

ANIMALS; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOME-WIDE ASSOCIATION STUDY; HEART; HISTONES; MALE; METHYLATION; MICE; MICE, KNOCKOUT; MUSCLE PROTEINS; NERVE TISSUE PROTEINS; PROTEIN METHYLTRANSFERASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, NOTCH1; REPRESSOR PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES;

MUS;

EID: 84862909047     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.315945     Document Type: Article

References (29)

1. Lee, Y., Song, A. J., Baker, R., Micales, B., Conway, S. J., and Lyons, G. E. (2000) Jumonji, a nuclear protein that is necessary for normal heart development. Circ. Res. 86, 932-938 (Pubitemid 30324304)
2. Takeuchi, T., Kojima, M., Nakajima, K., and Kondo, S. (1999) Jumonji gene is essential for the neurulation and cardiac development of mouse embryos with a C3H/He background. Mech. Dev. 86, 29-38 (Pubitemid 29371741)
3. Takeuchi, T., Yamazaki, Y., Katoh-Fukui, Y., Tsuchiya, R., Kondo, S., Motoyama, J., and Higashinakagawa, T. (1995) Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation. Genes Dev. 9, 1211-1222
4. Jung, J., Kim, T. G., Lyons, G. E., Kim, H. R., and Lee, Y. (2005) Jumonji regulates cardiomyocyte proliferation via interaction with retinoblastoma protein. J. Biol. Chem. 280, 30916-30923 (Pubitemid 41291823)
5. Mysliwiec, M. R., Bresnick, E. H., and Lee, Y. (2011) Endothelial Jarid2/ Jumonji is required for normal cardiac development and proper Notch1 expression. J. Biol. Chem. 286, 17193-17204
6. Conlon, R. A., Reaume, A. G., and Rossant, J. (1995) Notch1 is required for the coordinate segmentation of somites. Development 121, 1533-1545
7. Grego-Bessa, J., Luna-Zurita, L., del Monte, G., Bolós, V., Melgar, P., Aran- dilla, A., Garratt, A. N., Zang, H., Mukouyama, Y. S., Chen, H., Shou, W., Ballestar, E., Esteller, M., Rojas, A., Pérez-Pomares, J. M., and de la Pompa, J. L. (2007) Notch signaling is essential for ventricular chamber development. Dev. Cell 12, 415-429
8. Nottke, A., Colaiácovo, M. P., and Shi, Y. (2009) Developmental roles of the histone lysine demethylases. Development 136, 879-889
9. Nakayama, J., Rice, J. C., Strahl, B. D., Allis, C. D., and Grewal, S. I. (2001) Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292, 110-113
10. Peters, A. H., O'Carroll, D., Scherthan, H., Mechtler, K., Sauer, S., Schöfer, C., Weipoltshammer, K., Pagani, M., Lachner, M., Kohlmaier, A., Opravil, S., Doyle, M., Sibilia, M., and Jenuwein, T. (2001) Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107, 323-337 (Pubitemid 33049976)
11. Rea, S., Eisenhaber, F., O'Carroll, D., Strahl, B. D., Sun, Z. W., Schmid, M., Opravil, S., Mechtler, K., Ponting, C. P., Allis, C. D., and Jenuwein, T. (2000) Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406, 593-599 (Pubitemid 30641039)
12. Kim, T. G., Chen, J., Sadoshima, J., and Lee, Y. (2004) Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors. Mol. Cell. Biol. 24, 10151-10160 (Pubitemid 39507855)
13. Kim, T. G., Jung, J., Mysliwiec, M. R., Kang, S., and Lee, Y. (2005) Jumonji represses α-cardiac myosin heavy chain expression via inhibiting MEF2 activity. Biochem. Biophys. Res. Commun. 329, 544-553 (Pubitemid 40311779)
14. Kim, T. G., Kraus, J. C., Chen, J., and Lee, Y. (2003) Jumonji, a critical factor for cardiac development, functions as a transcriptional repressor. J. Biol. Chem. 278, 42247-42255 (Pubitemid 37310492)
15. Mysliwiec, M. R., Kim, T. G., and Lee, Y. (2007) Characterization of zinc finger protein 496 that interacts with Jumonji/Jarid2. FEBS Lett. 581, 2633-2640 (Pubitemid 46829104)
16. Shirato, H., Ogawa, S., Nakajima, K., Inagawa, M., Kojima, M., Tachibana, M., Shinkai, Y., and Takeuchi, T. (2009) A Jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9. J. Biol. Chem. 284, 733-739
17. Toyoda, M., Shirato, H., Nakajima, K., Kojima, M., Takahashi, M., Kubota, M., Suzuki-Migishima, R., Motegi, Y., Yokoyama, M., and Takeuchi, T. (2003) Jumonji down-regulates cardiac cell proliferation by repressing cyclin D1 expression. Dev. Cell 5, 85-97 (Pubitemid 36827344)
18. Landeira, D., Sauer, S., Poot, R., Dvorkina, M., Mazzarella, L., Jørgensen, H. F., Pereira, C. F., Leleu, M., Piccolo, F. M., Spivakov, M., Brookes, E., Pombo, A., Fisher, C., Skarnes, W. C., Snoek, T., Bezstarosti, K., Demmers, J., Klose, R. J., Casanova, M., Tavares, L., Brockdorff, N., and Merkenschlager, M., and Fisher, A. G. (2010) Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA polymerase II to developmental regulators. Nat. Cell Biol. 12, 618-624
19. Li, G., Margueron, R., Ku, M., Chambon, P., Bernstein, B. E., and Reinberg, D. (2010) Jarid2 and PRC2, partners in regulating gene expression. Genes Dev. 24, 368-380
20. Shen, X., Kim, W., Fujiwara, Y., Simon, M. D., Liu, Y., Mysliwiec, M. R., Yuan, G. C., Lee, Y., and Orkin, S. H. (2009) Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells. Cell 139, 1303-1314
21. Nielsen, A. L., Jørgensen, P., Lerouge, T., Cerviño, M., Chambon, P., and Losson, R. (2004) Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif. Mol. Cell. Biol. 24, 5184-5196 (Pubitemid 38738155)
22. Mejetta, S., Morey, L., Pascual, G., Kuebler, B., Mysliwiec, M. R., Lee, Y., Shiekhattar, R., Di Croce, L., and Benitah, S. A. (2011) Jarid2 regulates mouse epidermal stem cell activation and differentiation. EMBO J. 30, 3635-3646
23. Pasini, D., Cloos, P. A., Walfridsson, J., Olsson, L., Bukowski, J. P., Johansen, J. V., Bak, M., Tommerup, N., Rappsilber, J., and Helin, K. (2010) Jarid2 regulates binding of the polycomb repressive complex 2 to target genes in ES cells. Nature 464, 306-310
24. Peng, J. C., Valouev, A., Swigut, T., Zhang, J., Zhao, Y., Sidow, A., and Wysocka, J. (2009) Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell 139, 1290-1302
25. Zhang, Z., Jones, A., Sun, C. W., Li, C., Chang, C. W., Joo, H. Y., Dai, Q., Mysliwiec, M. R., Wu, L. C., Guo, Y., Yang, W., Liu, K., Pawlik, K. M., Erdjument-Bromage, H., Tempst, P., Lee, Y., Min, J., Townes, T. M., and Wang, H. (2011) PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming. Stem Cells 29, 229-240
26. Schultz, D. C., Ayyanathan, K., Negorev, D., Maul, G. G., and Rauscher, F. J., 3rd. (2002) SETDB1. A novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev. 16, 919-932 (Pubitemid 34408542)
27. Johnson, K. D., Kim, S. I., and Bresnick, E. H. (2006) Differential sensitivities of transcription factor target genes underlie cell type-specific gene expression profiles. Proc. Natl. Acad. Sci. U.S.A. 103, 15939-15944 (Pubitemid 44657571)
28. Tietjen, J. R., Zhang, D. W., Rodríguez-Molina, J. B., White, B. E., Akhtar, M. S., Heidemann, M., Li, X., Chapman, R. D., Shokat, K., Keles, S., Eick, D., and Ansari, A. Z. (2010) Chemical-genomic dissection of the CTD code. Nat. Struct. Mol. Biol. 17, 1154-1161
29. Buck, M. J., Nobel, A. B., and Lieb, J. D. (2005) ChIPOTle: A user-friendly tool for the analysis of ChIP-chip data. Genome Biology 6, R97