TWIST expression in hypopharyngeal cancer and the mechanism of TWIST-induced promotion of metastasis

Oncology Reports

Volumn 27, Issue 2, 2012, Pages 416-422

  Yu, Liang ^a   Lu, Sumei ^b   Tian, Jiajun ^a   Ma, Juke ^a   Li, Jianfeng ^b   Wang, Haibo ^a,b   Xu, Wei ^a  

^a SHANDONG UNIVERSITY   (China)

^b Shandong Clinic Research Institute   (China)

Author keywords

c fos; EMT; Hypopharyngeal carcinoma FaDu cells; Immunohistochemistry; Metastasis; MMP 9; TWIST

Indexed keywords

ACTIN; GELATINASE B; NERVE CELL ADHESION MOLECULE; PROTEIN C FOS; TRANSCRIPTION FACTOR TWIST; UVOMORULIN;

ADULT; ARTICLE; CANCER INVASION; CELL ADHESION; CELL CONTACT; CELL MIGRATION; CELL POLARITY; CELL STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOPHARYNX CANCER; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE METASTASIS; MALE; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRANSIENT EXPRESSION; TUMOR DIFFERENTIATION; TUMOR VOLUME;

CADHERINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, FOS; HUMANS; HYPOPHARYNGEAL NEOPLASMS; LYMPH NODES; MATRIX METALLOPROTEINASE 9; MICRORNAS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; TRANSFECTION; TUMOR BURDEN; TWIST TRANSCRIPTION FACTOR;

EID: 84862908668     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1481     Document Type: Article

References (29)

1. Smith RB, Apostolakis LW, Karnell LH, et al: The National Cancer Data Base report on cancer of the head and neck. Cancer 15: 1670-1680, 2003. (Pubitemid 37238624)
2. Lefebvre JL, Castelain B, De la Torre JC, Delobelle-Deroide A and Vankemmel B: Lymph node invasion in hypopharynx and lateral epilarynx: a prognostic factor. Head Neck Surg 10: 14-18, 1987. (Pubitemid 19098976)
3. Leon X, Quer M, Diez S, Orus C, Lopez-Pousa A and Burgues J: Second neoplasm in patients with head and neck cancer. Head Neck 21: 204-210, 1999. (Pubitemid 29144579)
4. Chen ZF and Behringer RR: Twist is required in head mesenchyme for cranial neural tube morphogenesis. Genes Dev 9: 686-699, 1995.
5. Yang J, Mani SA, Donaher JL, et al: TWIST, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117: 927-939, 2004. (Pubitemid 38798858)
6. Yuen HF, Chan YP, Wong ML, et al: Up-regulation of TWIST in oesophageal squamous cell carcinoma is associated with neoplastic transformation and distant metastasis. J Clin Pathol 60: 510-514, 2007. (Pubitemid 46867160)
7. Kwok WK, Ling MT, Lee TW, et al: Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target. Cancer Res 65: 5153-5162, 2005. (Pubitemid 40827324)
8. Kyo S, Sakaguchi J, Ohno S, et al: High TWIST expression is involved in infiltrative endometrial cancer and affects patient survival. Hum Pathol 37: 431-438, 2006.
9. Drake JM, Strohbehn G, Bair TB, Moreland JG and Henry MD: ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells. Mol Biol Cell 20: 2207-2217, 2009.
10. Cheng GZ, Zhang W and Wang LH: Regulation of cancer cell survival, migration, and invasion by twist: aKt2 comes to interplay. Cancer Res 8: 957-960, 2008. (Pubitemid 351272210)
11. Kajiyama H, Shibata K, Terauchi M, Yamashita M, Ino K, Nawa A and Kikkawa F: Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells. Int J Oncol 31: 277-283, 2007.
12. Hu E, Mueller E, Oliviero S, Papaioannou VE, Johnson R and Spiegelman BM: Targeted disruption of the c-fos gene demonstrates c-fos dependent and independent pathways for gene expression stimulated by growth factors or oncogenes. EMBO J 13: 3094-3103, 1994. (Pubitemid 24213461)
13. Yu L, Li HZ, Lu SM, Liu WW, Li JF, Wang HB and Xu W: Alteration in TWIST expression: possible role in paclitaxel-induced apoptosis in human laryngeal carcinoma Hep-2 cell line. Croat Med J 50: 536-542, 2009.
14. Sternlicht MD and Werb Z: How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 17: 463-516, 2001. (Pubitemid 33096184)
15. Li HC, Cao DC, Liu Y, et al: Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma. Breast Cancer Res Treat 88: 75-85, 2004. (Pubitemid 39524447)
16. Bland KI, Konstadoulakis MM, Vezeridis MP and Wanebo HJ: Oncogene protein co-expression. Value of Ha-ras, c-myc, c-fos, and p53 as prognostic discriminants for breast carcinoma. Ann Surg 221: 706-718, 1995.
17. Mikula M, Gotzmann J, Fischer AN, et al: The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis. Oncogene 22: 6725-6738, 2003. (Pubitemid 37372213)
18. Jin SP, Kim JH, Kim MA, Yang HK, Lee HE, Lee HS and Kim WH: Prognostic significance of loss of c-Fos protein in gastric carcinoma. Pathol Oncol Res 13: 284-289, 2007. (Pubitemid 351287308)
19. Lu S, Tian J, Lv Z, et al: The probable role of tumor stem cells for lymph node metastasis in supraglottic carcinoma. Pathol Oncol Res 17: 33-8, 2010.
20. Ou DL, Chien HF, Chen CL, Lin TC and Lin LI: Role of TWIST in head and neck carcinoma with lymph node metastasis. Anticancer Res 28: 1355-1359, 2008.
21. Hugo H, Ackland M.L, Blick T, Lawrence MG, Clements JA, Williams ED and Thompson EW: Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression. J Cell Physiol 213: 374-383, 2007. (Pubitemid 47509716)
22. Lee JM, Dedhar S, Kalluri R and Thompson EW: The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 172: 973-981, 2006.
23. Tran NL, Nagle RB, Cress AE and Heimark RL: N-Cadherin expression in human prostate carcinoma cell lines: an epithelial-mesenchymal transformation mediating adhesion with stromal cells. Am J Pathol 155: 787-798, 1999. (Pubitemid 29426824)
24. Hazan RB, Phillips GR, Qiao RF, Norton L and Aaronson SA: Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 148: 779-790, 2000.
25. Feng MY, Wang K, Shi QT, Yu XW and Geng JS: Gene expression profiling in TWIST-depleted gastric cancer cells. Anat Rec (Hoboken) 292: 262-270, 2009.
26. Milde-Langosch K: The Fos family of transcription factors and their role in tumourigenesis. Eur J Cancer 41: 2449-2461, 2005.
27. Fialka I, Schwarz H, Reichmann E, Oft M, Busslinger M and Beug H: The estrogen-dependent c-Jun ER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions. J Cell Biol 132: 1115-1132, 1996.
28. Chambers AF and Matrisian LM: Changing views of the role of matrix metalloproteinases in metastasis. J Natl Cancer Inst 89: 1260-1270, 1997. (Pubitemid 27371946)
29. Han S, Ritzenthaler JD, Sitaraman SV and Roman J: Fibronectin increases matrix metalloproteinase 9 expression through activation of c-Fos via extracellular-regulated kinase and phosphatidylinositol 3-kinase pathways in human lung carcinoma cells. J Biol Chem 281: 29614-29624, 2006. (Pubitemid 44536969)