Mifepristone-inducible caspase-1 expression in mouse embryonic stem cells eliminates tumor formation but spares differentiated cells in vitro and in vivo

Stem Cells

Volumn 30, Issue 2, 2012, Pages 169-179

  Wang, Yi ^a   Yang, Dehua ^a   Song, Lin ^a   Li, Ting ^a   Yang, Juan ^a   Zhang, Xiaojie ^a   Le, Weidong ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Caspase; Embryonic stem cell; Neural differentiation; Transplantation; Tumor cell purging

Indexed keywords

INTERLEUKIN 1BETA CONVERTING ENZYME; MIFEPRISTONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARCINOGENESIS; CELL DEATH; CELL DIFFERENTIATION; CELL SURVIVAL; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RISK REDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CASPASE 1; CELL DEATH; CELL SURVIVAL; DOPAMINERGIC NEURONS; EMBRYONIC STEM CELLS; ENZYME ACTIVATION; ENZYME ACTIVATORS; FEMALE; GENE EXPRESSION REGULATION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; MALE; MICE; MICE, NUDE; MIFEPRISTONE; NEOPLASMS, EXPERIMENTAL; PARKINSON DISEASE; REGENERATIVE MEDICINE; TERATOMA; TUMOR BURDEN;

MUS; MUS MUSCULUS;

EID: 84862908433     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1000     Document Type: Article

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