-
1
-
-
84862891107
-
Bucladesine sodium
-
Anonymous
-
Anonymous (1988) Bucladesine sodium. Drug Data Rep 10(7):542
-
(1988)
Drug Data Rep
, vol.10
, Issue.7
, pp. 542
-
-
-
2
-
-
33646128259
-
Dibutyryl cAMP influences endothelial progenitor cell recruitment during wound neovascularization
-
Asai J, Takenaka H, Katoh N, Kishimoto S (2006) Dibutyryl cAMP influences endothelial progenitor cell recruitment during wound neovascularization. J Invest Dermatol 126:1159-1167
-
(2006)
J Invest Dermatol
, vol.126
, pp. 1159-1167
-
-
Asai, J.1
Takenaka, H.2
Katoh, N.3
Kishimoto, S.4
-
3
-
-
0141717104
-
Bioactivatable, membrane-permeant analogs of cyclic nucleotides as biological tools for growth control of C6 glioma cells
-
DOI 10.1515/BC.2003.148
-
Bartsch M, Zorn-Kruppa M, Kuhl N, Genieser HG, Schwede F, JastorV B (2003) Bioactivatable, membrane-permeant analogs of cyclic nucleotides as biological tools for growth control of C6 glioma cells. Biol Chem 384:1321-1326 (Pubitemid 37168701)
-
(2003)
Biological Chemistry
, vol.384
, Issue.9
, pp. 1321-1326
-
-
Bartsch, M.1
Zorn-Kruppa, M.2
Kuhl, N.3
Genieser, H.-G.4
Schwede, F.5
Jastorff, B.6
-
4
-
-
0041524185
-
AWD 12-281, a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis
-
DOI 10.1211/0022357021585
-
Bäumer W, Gorr G, Hoppmann J, Ehinger AM, Rundfeldt C, Kietzmann M (2003) AWD 12-281, a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis. J Pharm Pharmacol 55:1107-1114 (Pubitemid 36998651)
-
(2003)
Journal of Pharmacy and Pharmacology
, vol.55
, Issue.8
, pp. 1107-1114
-
-
Baumer, W.1
Gorr, G.2
Hoppmann, J.3
Ehinger, A.M.4
Rundfeldt, C.5
Kietzmann, M.6
-
5
-
-
33947687574
-
Highly selective phosphodiesterase 4 inhibitors for the treatment of allergic skin diseases and psoriasis
-
Bäumer W, Hoppmann J, Rundfeldt C, Kietzmann M (2007) Highly selective phosphodiesterase 4 inhibitors for the treatment of allergic skin diseases and psoriasis. Inflamm Allergy Drug Targets 6:17-26 (Pubitemid 46488295)
-
(2007)
Inflammation and Allergy - Drug Targets
, vol.6
, Issue.1
, pp. 17-26
-
-
Baumer, W.1
Hoppmann, J.2
Rundfeldt, C.3
Kietzmann, M.4
-
6
-
-
77956251548
-
Pediatric atopic dermatitis: A review of the medical management
-
Carbone A, Siu A, Patel R (2010) Pediatric atopic dermatitis: a review of the medical management. Ann Pharmacother 44:1448-145.
-
(2010)
Ann Pharmacother
, vol.44
, pp. 1448-2145
-
-
Carbone, A.1
Siu, A.2
Patel, R.3
-
7
-
-
52949103280
-
Can the anti-inflammatory potential of PDE4 inhibitors be realized: Guarded optimism or wishful thinking?
-
Giembycz MA (2008) Can the anti-inflammatory potential of PDE4 inhibitors be realized: guarded optimism or wishful thinking? Br J Pharmacol 155:288-290
-
(2008)
Br J Pharmacol
, vol.155
, pp. 288-290
-
-
Giembycz, M.A.1
-
8
-
-
44349161096
-
An open-label, single-arm pilot study in patients with severe plaque-type psoriasis treated with an oral anti-inflammatory agent, apremilast
-
DOI 10.1185/030079908X301866
-
Gottlieb AB, Strober B, Krueger JG, Rohane P, Zeldis JB, Hu CC, Kipnis C (2008) An open-label, single-arm pilot study in patients with severe plaque-type psoriasis treated with an oral anti-inflammatory agent, apremilast. Curr Med Res Opin 24:1529-1538 (Pubitemid 351741586)
-
(2008)
Current Medical Research and Opinion
, vol.24
, Issue.5
, pp. 1529-1538
-
-
Gottlieb, A.B.1
Strober, B.2
Krueger, J.G.3
Rohane, P.4
Zeldis, J.B.5
Hu, C.C.6
Kipnis, C.7
-
9
-
-
0034128487
-
Correlation between in vitro cyclic adenosine monophosphate phosphodiesterase inhibition and in vivo anti-inflammatory effect
-
Goyarts E, Mammone T, Muizzuddin N, Marenus K, Maes D (2000) Correlation between in vitro cyclic adenosine monophosphate phosphodiesterase inhibition and in vivo anti-inflammatory effect. Skin Pharmacol Appl Skin Physiol 13:86-92 (Pubitemid 30195377)
-
(2000)
Skin Pharmacology and Applied Skin Physiology
, vol.13
, Issue.2
, pp. 86-92
-
-
Goyarts, E.1
Mammone, T.2
Muizzuddin, N.3
Marenus, K.4
Maes, D.5
-
10
-
-
0036379509
-
Randomized comparison of the type 4 phosphodiesterase inhibitor cipamfylline cream, cream vehicle and hydrocortisone 17-butyrate cream for the treatment of atopic dermatitis
-
Griffiths CE, Van Leent EJ, Gilbert M, Traulsen J (2002) Randomized comparison of the type 4 phosphodiesterase inhibitor cipamfylline cream, cream vehicle and hydrocortisone 17-butyrate cream for the treatment of atopic dermatitis. Br J Dermatol 147:299-307
-
(2002)
Br J Dermatol
, vol.147
, pp. 299-307
-
-
Griffiths, C.E.1
Van Leent, E.J.2
Gilbert, M.3
Traulsen, J.4
-
11
-
-
0018519274
-
Mechanism of demulsification of oilin- water emulsion in the centrifuge
-
Hahn AU, Mittal KL (1979) Mechanism of demulsification of oilin- water emulsion in the centrifuge. Colloid Polym Sci 257:959-96.
-
(1979)
Colloid Polym Sci
, vol.257
, pp. 959-996
-
-
Hahn, A.U.1
Mittal, K.L.2
-
12
-
-
0030056483
-
Type 4 phosphodiesterase inhibitors have clinical and in vitro anti-inflammatory effects in atopic dermatitis
-
Hanifin JM, Chan SC, Cheng JB, Tofte SJ, Henderson WR Jr, Kirby DS, Weiner ES (1996) Type 4 phosphodiesterase inhibitors have clinical and in vitro anti-inflammatory effects in atopic dermatitis. J Invest Dermatol 107:51-56 (Pubitemid 26236094)
-
(1996)
Journal of Investigative Dermatology
, vol.107
, Issue.1
, pp. 51-56
-
-
Hanifin, J.M.1
Chan, S.C.2
Cheng, J.B.3
Tofte, S.J.4
Henderson Jr., W.R.5
Kirby, D.S.6
Weiner, E.S.7
-
13
-
-
77952192978
-
Is PDE4 too difficult a drug target?
-
Higgs G (2010) Is PDE4 too difficult a drug target? Curr Opin Investig Drugs 11:495-498
-
(2010)
Curr Opin Investig Drugs
, vol.11
, pp. 495-498
-
-
Higgs, G.1
-
14
-
-
28644441704
-
The phosphodiesterase 4 inhibitor AWD 12-281 is active in a new guinea-pig model of allergic skin inflammation predictive of human skin penetration and suppresses both Th1 and Th2 cytokines in mice
-
DOI 10.1211/jpp.57.12.0011
-
Hoppmann J, Bäumer W, Galetzka C, Hofgen N, Kietzmann M, Rundfeldt C (2005) The phosphodiesterase 4 inhibitor AWD 12-281 is active in a new guinea-pig model of allergic skin inflammation predictive of human skin penetration and suppresses both Th1 and Th2 cytokines in mice. J Pharm Pharmacol 57:1609-1617 (Pubitemid 41752275)
-
(2005)
Journal of Pharmacy and Pharmacology
, vol.57
, Issue.12
, pp. 1609-1617
-
-
Hoppmann, J.1
Baumer, W.2
Galetzka, C.3
Hofgen, N.4
Kietzmann, M.5
Rundfeldt, C.6
-
15
-
-
27344449614
-
Keynote review: Phosphodiesterase-4 as a therapeutic target
-
DOI 10.1016/S1359-6446(05)03622-6, PII S1359644605036226
-
Houslay MD, Schafer P, Zhang KY (2005) Keynote review: phosphodiesterase- 4 as a therapeutic target. Drug Discov Today 10:1503-1519 (Pubitemid 41527193)
-
(2005)
Drug Discovery Today
, vol.10
, Issue.22
, pp. 1503-1519
-
-
Houslay, M.D.1
Schafer, P.2
Zhang, K.Y.J.3
-
16
-
-
0021856608
-
Activation of protein kinase isozymes by cyclic nucleotide analogs used singly or in combination. Principles for optimizing the isozyme specificity of analog combinations
-
DOI 10.1111/j.1432-1033.1985.tb09010.x
-
Ogreid D, Ekanger R, Suva RH, Miller JP, Sturm P, Corbin JD, Doskeland SO (1985) Activation of protein kinase isozymes by cyclic nucleotide analogs used singly or in combination. Principles for optimizing the isozyme specificity of analog combinations. Eur J Biochem 150:219-227 (Pubitemid 15069797)
-
(1985)
European Journal of Biochemistry
, vol.150
, Issue.1
, pp. 219-227
-
-
Ogreid, D.1
Ekanger, R.2
Suva, R.H.3
-
17
-
-
1642546494
-
Skin Irritation Studies on Bucladesine Sodium Ointment Containing a New Fragrance in Rabbits
-
Okumura Y, Goto M, Kato H, Takayama S, Mafune E, Yamada A, Tanaka K, Watanabe M, Nonomura H (2003) Skin irritation studies on bucladesine sodium ointment containing a new fragrance in rabbits. Jap Pharmacol Ther 31:1031-1037 (Pubitemid 38404842)
-
(2003)
Japanese Pharmacology and Therapeutics
, vol.31
, Issue.12
, pp. 1031-1037
-
-
Okumura, Y.1
Goto, M.2
Kato, H.3
Takayama, S.4
Mafune, E.5
Yamada, Y.6
Tanaka, K.7
Watanabe, M.8
Nonomura, H.9
-
18
-
-
79251588730
-
Reduction of exacerbations by the PDE4 inhibitor roflumilast - The importance of defining different subsets of patients with COPD
-
Rennard SI, Calverley PM, Goehring UM, Bredenbröker D, Martinez FJ (2011) Reduction of exacerbations by the PDE4 inhibitor roflumilast-the importance of defining different subsets of patients with COPD. Respir Res 12:18
-
(2011)
Respir Res
, vol.12
, pp. 18
-
-
Rennard, S.I.1
Calverley, P.M.2
Goehring, U.M.3
Bredenbröker, D.4
Martinez, F.J.5
-
19
-
-
0034130633
-
Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors
-
DOI 10.1016/S0162-3109(00)00185-5, PII S0162310900001855
-
Souness JE, Aldous D, Sargent C (2000) Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors. Immunopharmacology 47:127-162 (Pubitemid 30394536)
-
(2000)
Immunopharmacology
, vol.47
, Issue.2-3
, pp. 127-162
-
-
Souness, J.E.1
Aldous, D.2
Sargent, C.3
-
20
-
-
77955479420
-
Evolution of conventional therapy in atopic dermatitis
-
Wollenberg A, Schnopp C (2010) Evolution of conventional therapy in atopic dermatitis. Immunol Allergy Clin North Am 30:351-368
-
(2010)
Immunol Allergy Clin North Am
, vol.30
, pp. 351-368
-
-
Wollenberg, A.1
Schnopp, C.2
|