Inhibition of cyclooxygenase-2 modulates phenotypic switching of vascular smooth muscle cells during increased aortic blood flow

Heart and Vessels

Volumn 27, Issue 3, 2012, Pages 307-315

  Roan, Jun Neng ^a,b   Tsai, Yu Chuan ^b   Chen, I Wen ^b   Chang, Shih Wei ^b   Huang, Chien Chi ^b   Lam, Chen Fuh ^b  

^a TAINAN MUNICIPAL HOSPITAL   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Celecoxib; Collagen; Shear stress; Vascular remodeling

Indexed keywords

CELECOXIB; COLLAGEN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DESMIN; MYOSIN; MYOSIN HEAVY CHAIN;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; AORTA CONSTRICTION; AORTA FLOW; ARTERIAL WALL THICKNESS; ARTICLE; BLOOD FLOW; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEAVY CHAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHEAR STRESS; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ADMINISTRATION, ORAL; ANIMALS; AORTA; ARTERIOVENOUS FISTULA; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DESMIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; MYOSIN HEAVY CHAINS; MYOSIN TYPE II; PHENOTYPE; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; SULFONAMIDES; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 84862896542     PISSN: 09108327     EISSN: 16152573     Source Type: Journal    
DOI: 10.1007/s00380-011-0148-y     Document Type: Article

References (32)

1. Masuda H, Zhuang YJ, Singh TM, Kawamura K, Murakami M, Zarins CK, Glagov S (1999) Adaptive remodeling of internal elastic lamina and endothelial lining during flow-induced arterial enlargement. Arterioscler Thromb Vasc Biol 19: 2298-2307
2. Sho E, Nanjo H, Sho M, Kobayashi M, Komatsu M, Kawamura K, Xu C, Zarins CK, Masuda H (2004) Arterial enlargement, tortousity, and intimal thickening in response to sequential exposure to high and low wall shear stress. J Vasc Surg 39: 601-612
3. Kohlstedt K, Busse R, Fleming I (2005) Signaling via the angiotensin-converting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells. Hypertension 45: 126-132
4. Damirin A, Tomura H, Komachi M, Tobo M, Sato K, Mogi C, Nochi H, Tamoto K, Okajima F (2005) Sphingosine 1-phosphate receptors mediate the lipid-induced cAMP accumulation through cyclooxygenase-2/prostaglandin I2 pathway in human coronary artery smooth muscle cells. Mol Pharmacol 67: 1177-1185
5. Topper JN, Cai J, Falb D, Gimbrone MA Jr (1996) Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci USA 93: 10417-10422
6. Henrion D, Dechaux E, Dowell FJ, Maclour J, Samuel JL, Levy BI, Michel JB (1997) Alteration of flow-induced dilatation in mesenteric resistance arteries of L-NAME treated rats and its partial association with induction of cyclo-oxygenase-2. Br J Pharmacol 121: 83-90
7. Rudic RD, Brinster D, Cheng Y, Fries S, Song WL, Austin S, Coffman TM, FitzGerald GA (2005) COX-2-derived prostacyclin modulates vascular remodeling. Circ Res 96: 1240-1247
8. Owens GK, Kumar MS, Wamhoff BR (2004) Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84: 767-801
9. Orr AW, Lee MY, Lemmon JA, Yurdagul A Jr, Gomez MF, Bortz PD, Wamhoff BR (2009) Molecular mechanisms of collagen isotype-specific modulation of smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol 29: 225-231
10. Dilley RJ, McGeachie JK, Prendergast FJ (1987) A review of the proliferative behaviour, morphology and phenotypes of vascular smooth muscle. Atherosclerosis 63: 99-107
11. Buus Cl, Pourageaud F, Fazzi GE, Janssen G, Mulvany MJ, De Mey JG (2001) Smooth muscle cell changes during flow-related remodeling of rat mesenteric resistance arteries. Circ Res 89: 180-186
12. Nath KA, Kanakiriya SK, Grande JP, Croatt AJ, Katusic ZS (2003) Increased venous proinflammatory gene expression and intimal hyperplasia in an aortocaval fistula model in the rat. Am J Pathol 162: 2079-2090
13. Lam CF, Peterson TE, Richardson D, Croatt AJ, d'Uscio LV, Nath K, Katusic ZS (2006) Increased blood flow causes coordinated upregulation of arterial eNOS and biosynthesis of tetrahydrobiopterin. Am J Physiol Heart Circ Physiol 290: 786-793
14. Ben Driss A, Benessiano J, Poitevin P, Levy BI, Michel JB (1997) Arterial expansive remodeling induced by high flow rates. Am J Physiol 272: H851-H858
15. Ogawa M, Suzuki J, Hirata Y, Nagai R, Isobe M (2009) A critical role of COX-2 in the progression of neointimal formation after wire injury in mice. Expert Opin Ther Targets 13: 505-511
16. Lam CF, Liu YC, Tseng FL, Sung YH, Huang CC, Jiang MJ, Tsai YC (2007) High-dose morphine impairs vascular endothelial function by increased production of superoxide anions. Anesthesiology 106: 532-537
17. Bauersachs J, Bouloumie A, Fraccarollo D, Hu K, Busse R, Ertl G (1999) Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: role of enhanced vascular superoxide production. Circulation 100: 292-298
18. Rzucidlo EM, Martin KA, Powell RJ (2007) Regulation of vascular smooth muscle cell differentiation. J Vasc Surg 45: 25A-32A
19. Riha GM, Lin PH, Lumsden AB, Yao Q, Chen C (2005) Roles of hemodynamic forces in vascular cell differentiation. Ann BiomedEng 33: 772-779
20. Jiang GJ, Han M, Zheng B, Wen JK (2006) Hyperplasia suppressor gene associates with smooth muscle alpha-actin and is involved in the redifferentiation of vascular smooth muscle cells. Heart Vessels 21: 315-320
21. Shi ZD, Ji XY, Qazi H, Tarbell JM (2009) Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1. Am J Physiol Heart Circ Physiol 297: 1225-1234
22. Shi ZD, Abraham G, Tarbell JM (2010) Shear stress modulation of smooth muscle cell marker genes in 2-D and 3-D depends on mechanotransduction by heparan sulfate proteoglycans and ERK1/2. PLos One 5: e12196
23. Yoshida T, Kawai-Kowase K, Owens GK (2004) Forced expression of myocardin is not sufficient for induction of smooth muscle differentiation in multipotential embryonic cells. Arterioscler Thromb Vasc Biol 24: 1596-1601
24. Zou J, Chang TH, Chang H, Yaoita E, Yoshida Y, Nameta M, Yamamoto T, Jin X (2007) Time course of expression of intermediate filament protein vimentin, nestin and desmin in rat renal glomerular injury. Chin Med J (Engl) 120: 1203-1205
25. Silver FH, Horvath I, Foran DJ (2001) Viscoelasticity of the vessel wall: the role of collagen and elastic fibers. Crit Rev Biomed Eng 29: 279-301
26. Pasterkamp G, de Kleijn DP, Borst C (2000) Arterial remodeling in atherosclerosis, restenosis and after alteration of blood flow: potential mechanisms and clinical implications. Cardiovasc Res 45: 843-852
27. Medhora M, Bousamara M, Zhu D, Somberg L, Jacobs ER (2002) Upregulation of collagens detected by gene array in a model of flow-induced pulmonary vascular remodeling. Am J Physiol Heart Circ Physiol 282: 414-422
28. Wells SM, Langille BL, Lee JM, Adamson SL (1999) Determinants of mechanical properties in the developing ovine thoracic aorta. Am J Physiol Heart Circ Physiol 277: 1385-1391
29. Safar ME, Boudier HS (2005) Vascular development, pulse pressure, and the mechanisms of hypertension. Hypertension 46: 205-209
30. Tuttle RS (1966) Age-related changes in the sensitivity of rat aortic strips to norepinephrine and associated chemical and structural alterations. J Gerontol 21: 510-516
31. Bank AJ, Wang H, Jolte JE, Mullen K, Shammas R, Kubo SH (1996) Contribution of collagen, elastin, and smooth muscle to in vivo human brachial artery wall stress and elastic modulus. Circulation 94: 3263-3270
32. Bank AJ (1997) Physiologic aspects of drug therapy and large artery elastic properties. Vasc Med 2: 44-50