Sedation in adults receiving mechanical ventilation: Physiological and comfort outcomes

American Journal of Critical Care

Volumn 21, Issue 3, 2012, Pages

  Grap, Mary Jo ^a   Munro, Cindy L ^c   Wetzel, Paul A ^b   Best, Al M ^a   Ketchum, Jessica M ^a   Hamilton, V Anne ^a   Arief, Nyimas Y ^b   Pickler, Rita ^d   Sessler, Curtis N ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b Virginia Commonwealth University   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPNOTIC SEDATIVE AGENT; NARCOTIC ANALGESIC AGENT;

ACTIMETRY; ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; CONSCIOUS SEDATION; DEEP SEDATION; FEMALE; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MALE; METHODOLOGY; MIDDLE AGED; MONITORING; OXIMETRY; PROSPECTIVE STUDY; SOCIOECONOMICS;

ACTIGRAPHY; ADULT; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; CONSCIOUS SEDATION; DEEP SEDATION; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; INTENSIVE CARE UNITS; LENGTH OF STAY; MALE; MIDDLE AGED; MONITORING, PHYSIOLOGIC; OXIMETRY; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; SEVERITY OF ILLNESS INDEX; SOCIOECONOMIC FACTORS;

EID: 84862886126     PISSN: 10623264     EISSN: None     Source Type: Journal    
DOI: 10.4037/ajcc2012301     Document Type: Article

References (49)

1. Wunsch H, Kress JP. A new era for sedation in ICU patients. JAMA. 2009;301:542-544.
2. Weinert CR, Calvin AD. Epidemiology of sedation and sedation adequacy for mechanically ventilated patients in a medical and surgical intensive care unit. Crit Care Med. 2007;35:393-401.
3. Sessler CN, Grap MJ, Brophy GM. Multidisciplinary management of sedation and analgesia in critical care. Semin Respir Crit Care Med. 2001;22:211-225.
4. Jacobi J, Fraser GL, Coursin DB, et al. Task Force of the American College of Critical Care Medicine (ACCM) of the Society of Critical Care Medicine (SCCM), American Society of Health-System Pharmacists (ASHP), American College of Chest Physicians. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult [published correction appears in Crit Care Med. 2002;30(3):726]. Crit Care Med. 2002;30:119-141.
5. Sessler CN. Comfort and distress in the ICU: scope of the problem. Semin Respir Crit Care Med. 2001;22:111-114.
6. Abbott/American Association of Critical-Care Nurses; Saint Thomas Health System Sedation Expert Panel Members. Consensus conference on sedation assessment: a collaborative venture by Abbott Laboratories, American Association of Critical-Care Nurses, and Saint Thomas Health System. Crit Care Nurse. 2004;24(2):33-41.
7. Kollef MH, Levy NT, Ahrens TS, Schaiff R, Prentice D, Sherman G. The use of continuous i.v. sedation is associated with prolongation of mechanical ventilation. Chest. 1998; 114(2):541-548.
8. Barr J, Donner A. Optimal intravenous dosing strategies for sedatives and analgesics in the intensive care unit. Crit Care Clin. 1995;11:827-847.
9. Nseir S, Makris D, Mathieu D, Durocher A, Marquette CH. Intensive care unit-acquired infection as a side effect of sedation. Crit Care. 2010;14:R30.
10. Kramer AA, Zimmerman JE. A predictive model for the early identification of patients at risk for a prolonged intensive care unit length of stay. BMC Med Inform Decis Mak. 2010;10:27.
11. Rello J, Diaz E, Roque M, Valles J. Risk factors for developing pneumonia within 48 hours of intubation. Am J Respir Crit Care Med. 1999;159:1742-1746.
12. Ely EW, Shintani A, Truman B, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA. 2004;291(14):1753-1762.
13. Nelson BJ, Weinert CR, Bury CL, Marinelli WA, Gross CR. Intensive care unit drug use and subsequent quality of life in acute lung injury patients. Crit Care Med. 2000;28:3626-3630.
14. Boulain T. Unplanned extubations in the adult intensive care unit: a prospective multicenter study. Association des Réanimateurs du Centre-Ouest. Am J Respir Crit Care Med. 1998;157(4 pt 1):1131-1137.
15. Guttormson JL, Chlan L, Weinert C, Savik K. Factors influencing nurse sedation practices with mechanically ventilated patients: a US national survey. Intensive Crit Care Nurs. 2010;26:44-50.
16. Sessler CN, Pedram S. Protocolized and target-based sedation and analgesia in the ICU. Crit Care Clin. 2009;25:489-513, viii.
17. Magarey JM. Sedation of adult critically ill ventilated patients in intensive care units: a national survey. Aust Crit Care. 1997;10:90-93.
18. Dasta JF, Fuhrman TM, McCandles C. Patterns of prescribing and administering drugs for agitation and pain in patients in a surgical intensive care unit. Crit Care Med. 1994;22: 974-980.
19. Egerod I. Uncertain terms of sedation in ICU. How nurses and physicians manage and describe sedation for mechanically ventilated patients. J Clin Nurs. 2002;11:831-840.
20. Arias-Rivera S, Sanchez-Sanchez MM, Santos-Diaz R, et al. Effect of a nursing-implemented sedation protocol on weaning outcome. Crit Care Med. 2008;36:2054-2060.
21. Quenot JP, Ladoire S, Devoucoux F, et al. Effect of a nurseimplemented sedation protocol on the incidence of ventilatorassociated pneumonia. Crit Care Med. 2007;35:2031-2036.
22. Arabi Y, Haddad S, Hawes R, et al. Changing sedation practices in the intensive care unit-protocol implementation, multifaceted multidisciplinary approach and teamwork. Middle East J Anesthesiol. 2007;19(2):429-447.
23. Brook AD, Ahrens TS, Schaiff R, et al. Effect of a nursingimplemented sedation protocol on the duration of mechanical ventilation. Crit Care Med. 1999;27:2609-2615.
24. Marx WH, DeMaintenon NL, Mooney KF, et al. Cost reduction and outcome improvement in the intensive care unit. J Trauma. 1999;46:625-629.
25. Ibrahim EH, Kollef MH. Using protocols to improve the outcomes of mechanically ventilated patients: focus on weaning and sedation. Crit Care Clin. 2001;17:989-1001.
26. Grap MJ, Blecha T, Munro C. A description of patients' report of endotracheal tube discomfort. Intensive Crit Care Nurs. 2002;18:244-249.
27. Prichep LS, Gugino LD, John ER, et al. The Patient State Index as an indicator of the level of hypnosis under general anaesthesia. Br J Anaesth. 2004;92:393-399.
28. Chen X, Tang J, White PF, et al. A comparison of Patient State Index and bispectral index values during the perioperative period. Anesth Analg. 2002;95:1669-1674.
29. Schneider G, Heglmeier S, Schneider J, Tempel G, Kochs EF. Patient State Index (PSI) measures depth of sedation in intensive care patients. Intensive Care Med. 2004;30:213-216.
30. Kurup V, Ramani R, Atanassoff PG. Sedation after spinal anesthesia in elderly patients: a preliminary observational study with the PSA-4000. Can J Anaesth. 2004;51:562-565.
31. Drover D, Ortega HR. Patient State Index. Best Pract Res Clin Anaesthesiol. 2006;20:121-128.
32. Ramsay MA, Huddleston P, Henry C, Marcel R, Tai S. The Patient State Index is an indicator of inadequate pain management in the unresponsive ICU patient [abstract]. Anesthesiology. 2004;101:A349.
33. Grap MJ, Borchers CT, Munro CL, Elswick RK Jr, Sessler CN. Actigraphy in the critically ill: correlation with activity, agitation, and sedation. Am J Crit Care. 2005;14:52-60.
34. Mistraletti G, Taverna M, Sabbatini G, et al. Actigraphic monitoring in critically ill patients: preliminary results toward an "observation-guided sedation." J Crit Care. 2009;24:563-567.
35. Grap MJ, Hamilton VA, McNallen A, et al. Actigraphy: analyzing patient movement. Heart Lung. 2011;40(3):e52-e59.
36. Knaus WA, Wagner DP, Draper EA, et al. The APACHE III prognostic system: risk prediction of hospital mortality for critically ill hospitalized adults. Am J Respir Crit Care Med. 1991;100:1619-1636.
37. Knaus WA, Zimmerman JE, Wagner DP. APACHE-Acute Physiology and Chronic Health Evaluation: a physiologically based classification system. Crit Care Med. 1981;9:591-597.
38. Giangiuliani G, Mancini A, Gui D. Validation of a severity of illness score (APACHE II) in a surgical intensive care unit. Intensive Care Med. 1989;15:519-522.
39. Montgomery AB, Stager MA, Carrico CJ, Hudson LD. Causes of mortality in patients with the adult respiratory distress syndrome. Am Rev Respir Dis. 1985;132:485-489.
40. Roger-Moreau I, de Barbeyrac B, Ducoudre M, et al. Evaluation of bronchoalveolar lavage for the diagnosis of bacterial pneumonia in ventilated patients. Ann Biol Clin (Paris). 1992;50(8):587-591.
41. Jacobs S, Chang RW, Lee B, Bartlett FW. Continuous enteral feeding: a major cause of pneumonia among ventilated intensive care unit patients. JPEN J Parenter Enteral Nutr. 1990;14(4):353-356.
42. Sessler CN, Kollef MH, Hamilton A, Grap MJ, Jefferson D. Comparison of depth of sedation measured by PSA 4000 and Richmond Agitation-Sedation Scale (RASS) [abstract]. Chest. 2005;128(4):151S-152S.
43. Salluh JI, Soares M, Teles JM, et al. Delirium epidemiology in critical care (DECCA): an international study. Crit Care. 2010;14:R210.
44. Payen JF, Chanques G, Mantz J, et al. Current practices in sedation and analgesia for mechanically ventilated critically ill patients: a prospective multicenter patient-based study. Anesthesiology. 2007;106(4):687-695.
45. Ostermann ME, Keenan SP, Seiferling RA, Sibbald WJ. Sedation in the intensive care unit: a systematic review. JAMA. 2000;283:1451-1459.
46. Weinert CR, Chlan L, Gross C. Sedating critically ill patients: factors affecting nurses' delivery of sedative therapy. Am J Crit Care. 2001;10:156-165.
47. Rhoney DH, Murry KR. National survey of the use of sedating drugs, neuromuscular blocking agents, and reversal agents in the intensive care unit. J Intensive Care Med. 2003;18:139-145.
48. Schweickert WD, Pohlman MC, Pohlman AS, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet. 2009;373:1874-1882.
49. Morris PE, Goad A, Thompson C, et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med. 2008;36:2238-2243.