Triphenyltin impairs insulin secretion by decreasing glucose-induced NADP(H) and ATP production in hamster pancreatic β-cells

Toxicology

Volumn 299, Issue 2-3, 2012, Pages 165-171

  Miura, Yoshikazu ^a   Hori, Yuichi ^a   Kimura, Shinzo ^a   Hachiya, Hiroyuki ^a   Sakurai, Yuichirou ^a   Inoue, Kenichi ^a   Sawada, Tokihiko ^a   Kubota, Keiichi ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

ATP; Insulin secretion; Membrane potential; NAD(P)H; Triphenyltin

Indexed keywords

2 OXOISOCAPROIC ACID; ADENOSINE TRIPHOSPHATE; DIHYDROXYACETONE; FORMYCIN; FURA 2; GLUCOSE; GLYCERALDEHYDE; POTASSIUM CHANNEL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TOLBUTAMIDE; TRIPHENYLTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GLUCOSE METABOLISM; HAMSTER; HYPERGLYCEMIA; INSULIN RELEASE; MALE; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CRICETINAE; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; MALE; MEMBRANE POTENTIALS; MESOCRICETUS; NADP; ORGANOTIN COMPOUNDS; PATCH-CLAMP TECHNIQUES;

CRICETINAE;

EID: 84862876090     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.05.021     Document Type: Article

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