Facilitatory action of halothane at subanesthetic concentrations on glutamatergic excitatory synaptic transmission in the CA1 area of adult rat hippocampus

Neuroscience Letters

Volumn 337, Issue 3, 2003, Pages 139-142

  Otsubo, Toshiki ^a   Nakamura, Yoshitaka ^a   Nagai, Toshiaki ^a   Hori, Yuuichi ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Excitatory postsynaptic currents; Halothane; Hippocampus; Paired pulse facilitation; Patch clamp recording; Pyramidal Cells

Indexed keywords

HALOTHANE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TETRODOTOXIN;

ANESTHESIA; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; FACILITATION; GAS CHROMATOGRAPHY; HIPPOCAMPUS; MALE; MINIATURE ENDPLATE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SYNAPTIC TRANSMISSION;

EID: 0037434473     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)01319-8     Document Type: Article

References (20)

1. Andreasen M., Hablitz J.J. Paired-pulse facilitation in the dentate gyrus: a patch-clamp study in rat hippocampus in vitro. J. Neurophysiol. 72:1994;326-336.
2. Archer D.P., Samanani N., Roth S.H. Small-dose pentobarbital enhances synaptic transmission in rat hippocampus. Anesth. Analg. 93:2001;1521-1525.
3. Cook T.L., Smith M., Winter P.M., Starkweather J.A., Eger E.I. Effect of subanesthetic concentration of enflurane and halothane on human behavior. Anesth. Analg. 57:1978;434-440.
4. Cossart R., Epsztein J., Tyzio R., Becq H., Hirsch J., Ben-Ari Y., Crepel V. Quantal release of glutamate generates pure kainate and mixed AMPA/Kainate EPSCs in hippocampal neurons. Neuron. 35:2002;147-159.
5. Dildy-Mayfield J.E., Eger E.I., Harris R.A. Anesthetics produce subunit-selective actions on glutamate receptors. J. Pharmacol. Exp. Ther. 276:1996;1058-1065.
6. Drasner K. Low concentrations of halothane increase response to a noxious thermal stimulus and attenuate the antinociceptive effect of intraventricular but not intrathecal morphine. Anesthesiology. 94:2001;298-302.
7. Farthing D., Gehr L., Berger B., Fakhry I., Sica D. Simple method for simultaneous determination of halothane, enflurane, and isoflurane in Krebs solution using capillary gas chromatography. Biomed. Chromatogr. 11:1997;29-32.
8. Katz B. The transmission of impulses from nerve to muscle, and the subcellular unit of synaptic action. Proc. R. Soc. B. 155:1962;455-477.
9. Kirson E.D., Yaari Y., Perouansky M. Presynaptic and postsynaptic actions of halothane at glutamatergic synapses in the mouse hippocampus. Br. J. Pharmacol. 124:1998;1607-1614.
10. Komatsu H., Ohara T., Nogaya J., Yokono S., Ogli K. Subanesthetic concentrations of volatile anesthetics may enhance acquired avoidance training in ddN mice. Anesth. Analg. 73:1991;295-299.
11. MacIver M.B., Mikulec A.A., Amagasu S.M., Monroe F.A. Volatile anesthetics depress glutamate transmission via presynaptic actions. Anesthesiology. 85:1996;823-834.
12. MacIver M.B., Roth S.H. Inhalation anaesthetics exhibit pathway-specific and differential actions on hippocampal synaptic responses in vitro. Br. J. Anesth. 60:1988;680-691.
13. Manabe T., Wyllie D.J.A., Perkel D.J., Nicoll R.A. Modulation of synaptic transmission and Lont-Term Potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus. J. Neurophysiol. 70:1993;1451-1459.
14. Nishikawa K., MacIver M.B. Excitatory synaptic transmission mediated by NMDA receptors is more sensitive to isoflurane than are non-NMDA receptor-mediated responses. Anesthesiology. 92:2000;228-236.
15. Perouansky M.D.B., Salman M., Yaari Y. Effects of halothane on glutamate receptor-mediated excitatory postsynaptic currents. Anesthesiology. 83:1995;109-119.
16. Sommer B., Seeburg P.H. Glutamate receptor channels: novel properties and new clones. Trends Pharmacol. Sci. 13:1992;291-296.
17. Wakasugi M., Hirota K., Roth S.H., Ito Y. The effects of general anesthetics on excitatory and inhibitory synaptic transmission in area CA1 of the rat hippocampus in vitro. Anesth. Analg. 88:1999;676-680.
18. 2+ in rat hippocampal slices. Brain Res. 813:1998;351-358.
19. Yang N.C., Hwang K.L., Hung D.Z., Wuhh H.H., Ho W.M. Reliable gas chromatographic-mas spectrometric method combined with a headspace autosampler for isoflurane determination in blood. J. Chromatogr. B. 742:2000;277-282.
20. Zhang Y., Eger E.I., Dutton R.C., Sonner J.M. Inhaled anesthetics have hyperalgesic effects at 0.1 minimum alveolar anesthetic concentration. Anesth. Analg. 91:2000;462-466.