메뉴 건너뛰기




Volumn 41, Issue 1, 2012, Pages 219-227

Inhibition of tumor cell surface ATP synthesis by pigment epithelium-derived factor: Implications for antitumor activity

Author keywords

ATP; ATP synthase; ATP synthesis; Cell viability; PEDF; Tumor cell

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; BIOLOGICAL MARKER; F1 ADENOSINE TRIPHOSPHATE SYNTHASE BETA SUBUNIT; PICEATANNOL; POLYPEPTIDE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RECOMBINANT PIGMENT EPITHELIUM DERIVED FACTOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 84862875249     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1431     Document Type: Article
Times cited : (25)

References (45)
  • 3
    • 31544443514 scopus 로고    scopus 로고
    • Angiostatin is directly cytotoxic to tumor cells at low extracellular pH: A mechanism dependent on cell surface-associated ATP synthase
    • DOI 10.1158/0008-5472.CAN-05-2806
    • Chi SL and Pizzo SV: Angiostatin is directly cytotoxic to tumor cells at low extracellular pH: a mechanism dependent on cell surface-associated ATP synthase. Cancer Res 66: 875-882, 2006. (Pubitemid 43165953)
    • (2006) Cancer Research , vol.66 , Issue.2 , pp. 875-882
    • Chi, S.L.1    Pizzo, S.V.2
  • 5
    • 9344233830 scopus 로고    scopus 로고
    • Extracellular ATP is generated by ATP synthase complex in adipocyte lipid rafts
    • Kim BW, Choo HJ, Lee JW, Kim JH and Ko YG: Extracellular ATP is generated by ATP synthase complex in adipocyte lipid rafts. Exp Mol Med 36: 476-485, 2004.
    • (2004) Exp Mol Med , vol.36 , pp. 476-485
    • Kim, B.W.1    Choo, H.J.2    Lee, J.W.3    Kim, J.H.4    Ko, Y.G.5
  • 8
    • 33646857269 scopus 로고    scopus 로고
    • 1 ATPase: Metabolic and immunological functions
    • DOI 10.1097/01.mol.0000226120.27931.76, PII 0004143320060600000012
    • Champagne E, Martinez LO, Collet X and Barbaras R: Ecto-F1Fo ATP synthase/F1 ATPase: metabolic and immunological functions. Curr Opin Lipidol 17: 279-284, 2006. (Pubitemid 43786062)
    • (2006) Current Opinion in Lipidology , vol.17 , Issue.3 , pp. 279-284
    • Champagne, E.1    Martinez, L.O.2    Collet, X.3    Barbaras, R.4
  • 9
    • 77953735130 scopus 로고    scopus 로고
    • Targeting cell surface F1F0 ATP synthase in cancer therapy
    • Mowery YM and Pizzo SV: Targeting cell surface F1F0 ATP synthase in cancer therapy. Cancer Biol Ther 7: 1836-1838, 2008.
    • (2008) Cancer Biol Ther , vol.7 , pp. 1836-1838
    • Mowery, Y.M.1    Pizzo, S.V.2
  • 11
    • 0344011492 scopus 로고    scopus 로고
    • +-ATP synthase in the extracellular ATP synthesis and proliferation of human umbilical vein endothelial cells
    • +-ATP synthase in the extracellular ATP synthesis and proliferation of human umbilical vein endothelial cells. Mol Cancer Res 1: 931-939, 2003.
    • (2003) Mol Cancer Res , vol.1 , pp. 931-939
    • Arakaki, N.1    Nagao, T.2    Niki, R.3
  • 13
    • 62749120187 scopus 로고    scopus 로고
    • Identification of ATP synthase beta subunit (ATPB) on the cell surface as a non-small cell lung cancer (NSCLC) associated antigen
    • Lu ZJ, Song QF, Jiang SS, et al: Identification of ATP synthase beta subunit (ATPB) on the cell surface as a non-small cell lung cancer (NSCLC) associated antigen. BMC Cancer 9: 16, 2009.
    • (2009) BMC Cancer , vol.9 , pp. 16
    • Lu, Z.J.1    Song, Q.F.2    Jiang, S.S.3
  • 14
    • 77951241740 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor binds to cell-surface F(1)-ATP synthase
    • Notari L, Arakaki N, Mueller D, Meier S, Amaral J and Becerra SP: Pigment epithelium-derived factor binds to cell-surface F(1)-ATP synthase. FEBS J 277: 2192-2205, 2010.
    • (2010) FEBS J , vol.277 , pp. 2192-2205
    • Notari, L.1    Arakaki, N.2    Mueller, D.3    Meier, S.4    Amaral, J.5    Becerra, S.P.6
  • 15
    • 31644442359 scopus 로고    scopus 로고
    • Focus on molecules: Pigment epithelium-derived factor (PEDF)
    • Becerra SP: Focus on molecules: Pigment epithelium-derived factor (PEDF). Exp Eye Res 82: 739-740, 2006.
    • (2006) Exp Eye Res , vol.82 , pp. 739-740
    • Becerra, S.P.1
  • 16
    • 0036300131 scopus 로고    scopus 로고
    • PEDF: Anti-angiogenic guardian of ocular function
    • Bouck N: PEDF: anti-angiogenic guardian of ocular function. Trends Mol Med 8: 330-334, 2002.
    • (2002) Trends Mol Med , vol.8 , pp. 330-334
    • Bouck, N.1
  • 17
    • 65349165784 scopus 로고    scopus 로고
    • Characterization of PEDF: A multi-functional serpin family protein
    • Filleur S, Nelius T, de Riese W and Kennedy RC: Characterization of PEDF: a multi-functional serpin family protein. J Cell Biochem 106: 769-775, 2009.
    • (2009) J Cell Biochem , vol.106 , pp. 769-775
    • Filleur, S.1    Nelius, T.2    De Riese, W.3    Kennedy, R.C.4
  • 18
    • 77951055266 scopus 로고    scopus 로고
    • The neuroprotective role of PEDF: Implication for the therapy of neurological disorders
    • Yabe T, Sanagi T and Yamada H: The neuroprotective role of PEDF: implication for the therapy of neurological disorders. Curr Mol Med 10: 259-266, 2010.
    • (2010) Curr Mol Med , vol.10 , pp. 259-266
    • Yabe, T.1    Sanagi, T.2    Yamada, H.3
  • 20
    • 75349111879 scopus 로고    scopus 로고
    • In vitro and in vivo biological activity of PEDF against a range of tumors
    • Broadhead ML, Dass CR and Choong PF: In vitro and in vivo biological activity of PEDF against a range of tumors. Expert Opin Ther Targets 13: 1429-1438, 2009.
    • (2009) Expert Opin Ther Targets , vol.13 , pp. 1429-1438
    • Broadhead, M.L.1    Dass, C.R.2    Choong, P.F.3
  • 21
    • 33749158265 scopus 로고    scopus 로고
    • PEDF: A potential molecular therapeutic target with multiple anti-cancer activities
    • DOI 10.1016/j.molmed.2006.08.009, PII S1471491406001961
    • Ek ET, Dass CR and Choong PF: PEDF: a potential molecular therapeutic target with multiple anti-cancer activities. Trends Mol Med 12: 497-502, 2006. (Pubitemid 44468197)
    • (2006) Trends in Molecular Medicine , vol.12 , Issue.10 , pp. 497-502
    • Ek, E.T.H.1    Dass, C.R.2    Choong, P.F.M.3
  • 24
    • 0028803776 scopus 로고
    • Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop
    • Becerra SP, Sagasti A, Spinella P and Notario V: Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop. J Biol Chem 270: 25992-25999, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 25992-25999
    • Becerra, S.P.1    Sagasti, A.2    Spinella, P.3    Notario, V.4
  • 26
    • 67449101292 scopus 로고    scopus 로고
    • Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor
    • Bernard A, Gao-Li J, Franco CA, Bouceba T, Huet A and Li Z: Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factor. J Biol Chem 284: 10480-10490, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 10480-10490
    • Bernard, A.1    Gao-Li, J.2    Franco, C.A.3    Bouceba, T.4    Huet, A.5    Li, Z.6
  • 27
    • 79960341497 scopus 로고    scopus 로고
    • Identification of a novel inhibitor of the canonical Wnt pathway
    • Park K, Lee K, Zhang B, et al: Identification of a novel inhibitor of the canonical Wnt pathway. Mol Cell Biol 31: 3038-3051, 2011.
    • (2011) Mol Cell Biol , vol.31 , pp. 3038-3051
    • Park, K.1    Lee, K.2    Zhang, B.3
  • 28
    • 0032575347 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: Analysis of the binding site
    • DOI 10.1021/bi9802317
    • Alberdi E, Hyde CC and Becerra SP: Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: analysis of the binding site. Biochemistry 37: 10643-10652, 1998. (Pubitemid 28357865)
    • (1998) Biochemistry , vol.37 , Issue.30 , pp. 10643-10652
    • Alberdi, E.1    Hyde, C.C.2    Becerra, S.P.3
  • 29
    • 57749093004 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor binds to hyaluronan. Mapping of a hyaluronan binding site
    • Becerra SP, Perez-Mediavilla LA, Weldon JE, et al: Pigment epithelium-derived factor binds to hyaluronan. Mapping of a hyaluronan binding site. J Biol Chem 283: 33310-33320, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 33310-33320
    • Becerra, S.P.1    Perez-Mediavilla, L.A.2    Weldon, J.E.3
  • 30
    • 0037160083 scopus 로고    scopus 로고
    • Mapping the type I collagen-binding site on pigment epithelium-derived factor: Implications for its antiangiogenic activity
    • DOI 10.1074/jbc.M208339200
    • Meyer C, Notari L and Becerra SP: Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity. J Biol Chem 277: 45400-45407, 2002. (Pubitemid 36159148)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.47 , pp. 45400-45407
    • Meyer, C.1    Notari, L.2    Becerra, S.P.3
  • 31
    • 77949883008 scopus 로고    scopus 로고
    • Effects of human recombinant PEDF protein and PEDF-derived peptide 34-mer on choroidal neovascularization
    • Amaral J and Becerra SP: Effects of human recombinant PEDF protein and PEDF-derived peptide 34-mer on choroidal neovascularization. Invest Ophthalmol Vis Sci 51: 1318-1326, 2010.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 1318-1326
    • Amaral, J.1    Becerra, S.P.2
  • 33
    • 63449111231 scopus 로고    scopus 로고
    • Short pigment epithelial-derived factor-derived peptide inhibits angiogenesis and tumor growth
    • Mirochnik Y, Aurora A, Schulze-Hoepfner FT, et al: Short pigment epithelial-derived factor-derived peptide inhibits angiogenesis and tumor growth. Clin Cancer Res 15: 1655-1663, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 1655-1663
    • Mirochnik, Y.1    Aurora, A.2    Schulze-Hoepfner, F.T.3
  • 34
    • 0033615612 scopus 로고    scopus 로고
    • Binding of pigment epithelium-derived factor (PEDF) to retinoblastoma cells and cerebellar granule neurons. Evidence for a PEDF receptor
    • Alberdi E, Aymerich MS and Becerra SP: Binding of pigment epithelium-derived factor (PEDF) to retinoblastoma cells and cerebellar granule neurons. Evidence for a PEDF receptor. J Biol Chem 274: 31605-31612, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 31605-31612
    • Alberdi, E.1    Aymerich, M.S.2    Becerra, S.P.3
  • 35
    • 0036849639 scopus 로고    scopus 로고
    • Identification of the neuroprotective molecular region of pigment epithelium-derived factor and its binding sites on motor neurons
    • Bilak MM, Becerra SP, Vincent AM, Moss BH, Aymerich MS and Kuncl RW: Identification of the neuroprotective molecular region of pigment epithelium-derived factor and its binding sites on motor neurons. J Neurosci 22: 9378-9386, 2002. (Pubitemid 35356181)
    • (2002) Journal of Neuroscience , vol.22 , Issue.21 , pp. 9378-9386
    • Bilak, M.M.1    Patricia, B.S.2    Vincent, A.M.3    Moss, B.H.4    Aymerich, M.S.5    Kuncl, R.W.6
  • 36
    • 0030449154 scopus 로고    scopus 로고
    • Recombinant human pigment epithelium-derived factor (PEDF): Characterization of PEDF overexpressed and secreted by eukaryotic cells
    • Stratikos E, Alberdi E, Gettins PG and Becerra SP: Recombinant human pigment epithelium-derived factor (PEDF): characterization of PEDF overexpressed and secreted by eukaryotic cells. Protein Sci 5: 2575-2582, 1996. (Pubitemid 26424870)
    • (1996) Protein Science , vol.5 , Issue.12 , pp. 2575-2582
    • Stratikos, E.1    Alberdi, E.2    Gettins, P.G.W.3    Becerra, S.P.4
  • 37
    • 3843067664 scopus 로고    scopus 로고
    • Human microvascular endothelial cells immortalized with human telomerase catalytic protein: A model for the study of in vitro angiogenesis
    • DOI 10.1016/j.bbrc.2004.07.033, PII S0006291X04015165
    • Shao R and Guo X: Human microvascular endothelial cells immortalized with human telomerase catalytic protein: a model for the study of in vitro angiogenesis. Biochem Biophys Res Commun 321: 788-794, 2004. (Pubitemid 39044379)
    • (2004) Biochemical and Biophysical Research Communications , vol.321 , Issue.4 , pp. 788-794
    • Shao, R.1    Guo, X.2
  • 38
    • 84875412317 scopus 로고    scopus 로고
    • Image Processing with ImageJ
    • Rasband WS: Image Processing with ImageJ. Biophotonics Int 11: 36-42, 1997.
    • (1997) Biophotonics Int , vol.11 , pp. 36-42
    • Rasband, W.S.1
  • 41
    • 0036173620 scopus 로고    scopus 로고
    • Piceatannol, a natural analog of resveratrol, inhibits progression through the s phase of the cell cycle in colorectal cancer cell lines
    • Wolter F, Clausnitzer A, Akoglu B and Stein J: Piceatannol, a natural analog of resveratrol, inhibits progression through the S phase of the cell cycle in colorectal cancer cell lines. J Nutr 132: 298-302, 2002. (Pubitemid 34135611)
    • (2002) Journal of Nutrition , vol.132 , Issue.2 , pp. 298-302
    • Wolter, F.1    Clausnitzer, A.2    Akoglu, B.3    Stein, J.4
  • 42
  • 44
    • 57549108331 scopus 로고    scopus 로고
    • ATP synthase and the actions of inhibitors utilized to study its roles in human health, disease, and other scientific areas
    • Hong S and Pedersen PL: ATP synthase and the actions of inhibitors utilized to study its roles in human health, disease, and other scientific areas. Microbiol Mol Biol Rev 72: 590-641, 2008.
    • (2008) Microbiol Mol Biol Rev , vol.72 , pp. 590-641
    • Hong, S.1    Pedersen, P.L.2
  • 45
    • 49249136184 scopus 로고    scopus 로고
    • Dual functions of a monoclonal antibody against cell surface F1F0 ATP synthase on both HUVEC and tumor cells
    • Zhang X, Gao F, Yu LL, et al: Dual functions of a monoclonal antibody against cell surface F1F0 ATP synthase on both HUVEC and tumor cells. Acta Pharmacol Sin 29: 942-950, 2008.
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 942-950
    • Zhang, X.1    Gao, F.2    Yu, L.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.