Oligomerized alpha-helical KALA peptides with pendant arms bearing cell-adhesion, DNA-binding and endosome-buffering domains as efficient gene transfection vectors

Biomaterials

Volumn 33, Issue 26, 2012, Pages 6284-6291

  Guo, Xin Dong ^a,b   Wiradharma, Nikken ^a   Liu, Shao Qiong ^a   Zhang, Li Juan ^b   Khan, Majad ^a   Qian, Yu ^b   Yang, Yi Yan ^a  

^a INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

^b SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Alpha helicity; Cationic peptide; Gene transfection; KALA; Oligomerization; RGD

Indexed keywords

ALPHA-HELICITY; CATIONIC PEPTIDES; GENE TRANSFECTION; KALA; RGD;

ADHESION; AMINO ACIDS; CYTOTOXICITY; DNA; EFFICIENCY; GENE EXPRESSION; GENE TRANSFER; MOLECULAR BIOLOGY; OLIGOMERIZATION; OPTIMIZATION; PARTICLE SIZE; PEPTIDES; ZETA POTENTIAL;

OLIGOMERS;

DISULFIDE; HISTIDINE; LUCIFERASE; LYSINE; PEPTIDES AND PROTEINS; PROTEIN CC14; PROTEIN KC20; PROTEIN KC23; PROTEIN RC23; PROTEIN RC29; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CELL ADHESION; CIRCULAR DICHROISM; CYTOTOXICITY; DNA BINDING; DNA PROTEIN COMPLEX; ENDOSOME; GENE EXPRESSION; GENETIC DISORDER; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; OLIGOMERIZATION; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; ZETA POTENTIAL;

CELL ADHESION; DNA; DNA-BINDING PROTEINS; ENDOSOMES; GENETIC VECTORS; HEP G2 CELLS; HUMANS; PEPTIDES; PROTEIN MULTIMERIZATION; TRANSFECTION;

TETRA;

EID: 84862870761     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.05.033     Document Type: Article

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