Gastroprotective effect of anti-cancer compound rohitukine: Possible role of gastrin antagonismand H + K +-ATPase inhibition

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 385, Issue 3, 2012, Pages 277-286

  Singh, Neetu ^a   Singh, Pratibha ^a   Shrivastva, Shishir ^a   Mishra, Sunil Kumar ^a   Lakshmi, Vijai ^a   Sharma, Rolee ^b   Palit, Gautam ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b INTEGRAL UNIVERSITY   (India)

Author keywords

CCK 2 receptor; Gastric ulcer; Gastrin; H + K + ATPase; Intracellular Ca 2+ ; Rohitukine

Indexed keywords

ALCOHOL; ANTINEOPLASTIC AGENT; ANTIULCER AGENT; CALCIUM ION; CHROMAN DERIVATIVE; GASTRIN; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; MUCIN; OMEPRAZOLE; PEPSIN A; PLANT EXTRACT; PROSTAGLANDIN E2; ROHITUKINE; SUCRALFATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL PROTECTION; CELL SUSPENSION; CONTROLLED STUDY; CYTOSOL; DISEASE MODEL; DOSE RESPONSE; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENCY; DYSOXYLUM BINECTARIFERUM; ENZYME INHIBITION; GASTRIC HYPERACIDITY; GASTRIN BLOOD LEVEL; IN VITRO STUDY; MELIACEAE; MICROSOME; NONHUMAN; PEPTIC ULCER; PROSTAGLANDIN BLOOD LEVEL; PYLORUS; RAT; STOMACH EROSION; STOMACH LESION; STOMACH PARIETAL CELL; STOMACH PROTECTION;

ANIMALS; ANTI-ULCER AGENTS; ANTINEOPLASTIC AGENTS; CALCIUM; CHROMONES; COLD TEMPERATURE; DISEASE MODELS, ANIMAL; ETHANOL; GASTRINS; H(+)-K(+)-EXCHANGING ATPASE; LIGATION; MELIACEAE; MICROSOMES; PIPERIDINES; PLANT BARK; PYLORUS; RATS; RATS, SPRAGUE-DAWLEY; RESTRAINT, PHYSICAL; STOMACH ULCER; STRESS, PHYSIOLOGICAL;

EID: 84862849382     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-011-0711-1     Document Type: Article

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