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Volumn 21, Issue 3, 2012, Pages 141-147

Presence of GAD65 autoantibodies in the serum of children with autism or ADHD

Author keywords

ADHD; Autism; Autoantibodies; Brain and development; GAD; Serum

Indexed keywords

GLUTAMATE DECARBOXYLASE 65 ANTIBODY; IMMUNOGLOBULIN G;

EID: 84862843376     PISSN: 10188827     EISSN: 1435165X     Source Type: Journal    
DOI: 10.1007/s00787-012-0245-1     Document Type: Article
Times cited : (51)

References (34)
  • 1
    • 0036807537 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase autoantibodies and neurological disorders
    • DOI 10.1007/s100720200055
    • Vianello M, Tavolato B, Giometto B (2002) Glutamic acid decarboxylase autoantibodies and neurological disorders. Neurol Sci 23(4): 145-151 (Pubitemid 35345488)
    • (2002) Neurological Sciences , vol.23 , Issue.4 , pp. 145-151
    • Vianello, M.1    Tavolato, B.2    Giometto, B.3
  • 3
    • 71749101489 scopus 로고    scopus 로고
    • An autoantibody inhibitory to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease
    • Chattopadhyay S, Ito M, Cooper JD, Brooks AI, Curran TM, Powers JM, Pearce DA (2002) An autoantibody inhibitory to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease. Hum Mol Genet 11(12): 1421-1431
    • (2002) Hum Mol Genet , vol.11 , Issue.12 , pp. 1421-1431
    • Chattopadhyay, S.1    Ito, M.2    Cooper, J.D.3    Brooks, A.I.4    Curran, T.M.5    Powers, J.M.6    Pearce, D.A.7
  • 4
    • 0004235298 scopus 로고
    • American Psychiatric Association, 4th edn American Psychiatric Association, Washington
    • American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Association, Washington
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 5
    • 63449095687 scopus 로고    scopus 로고
    • Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: An in situ hybridization study
    • Yip J, Soghomonian JJ, Blatt GJ (2009) Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study. Autism Res 2(1): 50-59
    • (2009) Autism Res , vol.2 , Issue.1 , pp. 50-59
    • Yip, J.1    Soghomonian, J.J.2    Blatt, G.J.3
  • 6
    • 0037108019 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices
    • Fatemi SH, Halt AR, Stary JM, Kanodia R, Schulz SC, Realmuto GR (2002) Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices. Biol Psychiatry 52(8): 805-810
    • (2002) Biol Psychiatry , vol.52 , Issue.8 , pp. 805-810
    • Fatemi, S.H.1    Halt, A.R.2    Stary, J.M.3    Kanodia, R.4    Schulz, S.C.5    Realmuto, G.R.6
  • 7
    • 0021838287 scopus 로고
    • Histoanatomic observations of the brain in early infantile autism
    • Bauman M, Kemper TL (1985) Histoanatomic observations of the brain in early infantile autism. Neurology 35(6): 866-874 (Pubitemid 15025292)
    • (1985) Neurology , vol.35 , Issue.6 , pp. 866-874
    • Bauman, M.1    Kemper, T.L.2
  • 8
    • 45649084333 scopus 로고    scopus 로고
    • A pathogenetic model of autism involving Purkinje cell loss through anti-GAD antibodies
    • Rout UK, Dhossche DM (2008) A pathogenetic model of autism involving Purkinje cell loss through anti-GAD antibodies. Med Hypotheses 71(2): 218-221
    • (2008) Med Hypotheses , vol.71 , Issue.2 , pp. 218-221
    • Rout, U.K.1    Dhossche, D.M.2
  • 9
    • 84862874694 scopus 로고
    • American-Psychiatric-Association: Diagnostic and statistical manual of mental disorders: DSM-IV-TR
    • Fourth Edition
    • American-Psychiatric-Association: Diagnostic and statistical manual of mental disorders: DSM-IV-TR. Book: ISBN 08904202 54 1994, Fourth Edition
    • (1994) Book: ISBN 08904202 , vol.54
  • 12
    • 78349293844 scopus 로고    scopus 로고
    • The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood
    • Lichtenstein P, Carlstrom E, Rastam M, Gillberg C, Anckarsater H (2010) The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood. Am J Psychiatry 167(11): 1357-1363
    • (2010) Am J Psychiatry , vol.167 , Issue.11 , pp. 1357-1363
    • Lichtenstein, P.1    Carlstrom, E.2    Rastam, M.3    Gillberg, C.4    Anckarsater, H.5
  • 13
    • 0029035520 scopus 로고
    • Determination of anti GAD65 autoantibodies with an ELISA before and after standardization with the new international reference serum
    • Pfutzner A, Forst T, Ambrosch A, Schmitz H, Lichtwald K, Beyer J (1995) Determination of anti GAD65 autoantibodies with an ELISA before and after standardization with the new international reference serum. Exp Clin Endocrinol Diabetes 103(2): 123-125
    • (1995) Exp Clin Endocrinol Diabetes , vol.103 , Issue.2 , pp. 123-125
    • Pfutzner, A.1    Forst, T.2    Ambrosch, A.3    Schmitz, H.4    Lichtwald, K.5    Beyer, J.6
  • 15
    • 34250683023 scopus 로고    scopus 로고
    • Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: An open label, phase I trial
    • DOI 10.1016/S0140-6736(07)60982-9, PII S0140673607609829
    • Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA, Bland RJ, Young D, Strybing K, Eidelberg D et al (2007) Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet 369(9579): 2097-2105 (Pubitemid 46935946)
    • (2007) Lancet , vol.369 , Issue.9579 , pp. 2097-2105
    • Kaplitt, M.G.1    Feigin, A.2    Tang, C.3    Fitzsimons, H.L.4    Mattis, P.5    Lawlor, P.A.6    Bland, R.J.7    Young, D.8    Strybing, K.9    Eidelberg, D.10    During, M.J.11
  • 17
    • 77957658735 scopus 로고    scopus 로고
    • Philipsen A: H(1)-MR-spectroscopy of cerebellum in adult attention deficit/hyperactivity disorder
    • Tebarzt van Elst L, Buechert M, Maier S, Matthies S, Ebert D, Hesslinger B
    • Perlov E (2010) Tebarzt van Elst L, Buechert M, Maier S, Matthies S, Ebert D, Hesslinger B, Philipsen A: H(1)-MR-spectroscopy of cerebellum in adult attention deficit/hyperactivity disorder. J Psychiatr Res 44(14): 938-943
    • (2010) J Psychiatr Res , vol.44 , Issue.14 , pp. 938-943
    • Perlov, E.1
  • 18
    • 56949085021 scopus 로고    scopus 로고
    • Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders
    • Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral DG, Van de Water J (2009) Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders. Brain Behav Immun 23(1): 64-74
    • (2009) Brain Behav Immun , vol.23 , Issue.1 , pp. 64-74
    • Wills, S.1    Cabanlit, M.2    Bennett, J.3    Ashwood, P.4    Amaral, D.G.5    Van De Water, J.6
  • 19
    • 0343807514 scopus 로고    scopus 로고
    • Broken dogma: Penetration of autoantibodies into living cells
    • DOI 10.1016/0167-5699(96)80613-X
    • Alarcon-Segovia D, Ruiz-Arguelles A, Llorente L (1996) Broken dogma: penetration of autoantibodies into living cells. Immunol Today 17(4): 163-164 (Pubitemid 26113083)
    • (1996) Immunology Today , vol.17 , Issue.4 , pp. 163-164
    • Alarcon-Segovia, D.1    Ruiz-Arguelles, A.2    Llorente, L.3
  • 20
    • 0021240533 scopus 로고
    • Retrograde transport of dopamine β-hydroxylase antibodies in sympathetic neurons: Effects of drugs modifying noradrenergic transmission
    • DOI 10.1016/0006-8993(84)91097-7
    • Lees GJ, Horsburgh RJ (1984) Retrograde transport of dopamine beta-hydroxylase antibodies in sympathetic neurons: effects of drugs modifying noradrenergic transmission. Brain Res 301(2): 281-286 (Pubitemid 14102560)
    • (1984) Brain Research , vol.301 , Issue.2 , pp. 281-286
    • Lees, G.J.1    Horsburgh, R.J.2
  • 21
    • 0021277747 scopus 로고
    • Retrograde axonal transport of antibodies to synaptic membrane components
    • DOI 10.1016/0006-8993(84)90874-6
    • Wenthold RJ, Skaggs KK, Reale RR (1984) Retrograde axonal transport of antibodies to synaptic membrane components. Brain Res 304(1): 162-165 (Pubitemid 14123327)
    • (1984) Brain Research , vol.304 , Issue.1 , pp. 162-165
    • Wenthold, R.J.1    Skaggs, K.K.2    Reale, R.R.3
  • 23
    • 0036953160 scopus 로고    scopus 로고
    • Passage of amyloid β protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease
    • DOI 10.1016/S0196-9781(02)00261-9, PII S0196978102002619
    • Banks WA, Terrell B, Farr SA, Robinson SM, Nonaka N, Morley JE (2002) Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease. Peptides 23(12): 2223-2226 (Pubitemid 36092057)
    • (2002) Peptides , vol.23 , Issue.12 , pp. 2223-2226
    • Banks, W.A.1    Terrell, B.2    Farr, S.A.3    Robinson, S.M.4    Nonaka, N.5    Morley, J.E.6
  • 24
    • 34447622675 scopus 로고    scopus 로고
    • Anti-amyloid beta protein antibody passage across the blood-brain barrier in the SAMP8 mouse model of Alzheimer's disease: An age-related selective uptake with reversal of learning impairment
    • DOI 10.1016/j.expneurol.2007.05.005, PII S0014488607001987
    • Banks WA, Farr SA, Morley JE, Wolf KM, Geylis V, Steinitz M (2007) Anti-amyloid beta protein antibody passage across the blood-brain barrier in the SAMP8 mouse model of Alzheimer's disease: an age-related selective uptake with reversal of learning impairment. Exp Neurol 206(2): 248-256 (Pubitemid 47094769)
    • (2007) Experimental Neurology , vol.206 , Issue.2 , pp. 248-256
    • Banks, W.A.1    Farr, S.A.2    Morley, J.E.3    Wolf, K.M.4    Geylis, V.5    Steinitz, M.6
  • 26
    • 0021812730 scopus 로고
    • Demonstration of regional blood-brain barrier permeability in human brain
    • DOI 10.1016/0304-3940(85)90500-2
    • Landas S, Fischer J, Wilkin LD, Mitchell LD, Johnson AK, Turner JW, Theriac M, Moore KC (1985) Demonstration of regional blood-brain barrier permeability in human brain. Neurosci Lett 57(3): 251-256 (Pubitemid 15057099)
    • (1985) Neuroscience Letters , vol.57 , Issue.3 , pp. 251-256
    • Landas, S.1    Fischer, J.2    Wilkin, L.D.3
  • 29
    • 0034175505 scopus 로고    scopus 로고
    • Presynaptic impairment of cerebellar inhibitory synapses by an autoantibody to glutamate decarboxylase
    • DOI 10.1016/S0022-510X(00)00272-0, PII S0022510X00002720
    • Mitoma H, Song SY, Ishida K, Yamakuni T, Kobayashi T, Mizusawa H (2000) Presynaptic impairment of cerebellar inhibitory synapses by an autoantibody to glutamate decarboxylase. J Neurol Sci 175(1): 40-44 (Pubitemid 30227482)
    • (2000) Journal of the Neurological Sciences , vol.175 , Issue.1 , pp. 40-44
    • Mitoma, H.1    Song, S.-Y.2    Ishida, K.3    Yamakuni, T.4    Kobayashi, T.5    Mizusawa, H.6
  • 30
    • 0037445615 scopus 로고    scopus 로고
    • B-receptor- mediated synaptic responses by autoantibodies to glutamic acid decarboxylase
    • DOI 10.1016/S0022-510X(02)00423-9
    • Mitoma H, Ishida K, Shizuka-Ikeda M, Mizusawa H (2003) Dual impairment of GABAA- and GABAB-receptor-mediated synaptic responses by autoantibodies to glutamic acid decarboxylase. J Neurol Sci 208(1-2): 51-56 (Pubitemid 36294154)
    • (2003) Journal of the Neurological Sciences , vol.208 , Issue.1-2 , pp. 51-56
    • Mitoma, H.1    Ishida, K.2    Shizuka-Ikeda, M.3    Mizusawa, H.4
  • 31
    • 45849112873 scopus 로고    scopus 로고
    • Reversibility of cerebellar GABAergic synapse impairment induced by anti-glutamic acid decarboxylase autoantibodies
    • Ishida K, Mitoma H, Mizusawa H (2008) Reversibility of cerebellar GABAergic synapse impairment induced by anti-glutamic acid decarboxylase autoantibodies. J Neurol Sci 271(1-2): 186-190
    • (2008) J Neurol Sci , vol.271 , Issue.1-2 , pp. 186-190
    • Ishida, K.1    Mitoma, H.2    Mizusawa, H.3
  • 32
    • 1542786486 scopus 로고    scopus 로고
    • The neuropathology of the autism spectrum disorders: What have we learned?
    • discussion 122-118, 281-197
    • Bauman ML, Kemper TL: The neuropathology of the autism spectrum disorders: what have we learned? Novartis Found Symp 2003, 251: 112-122; discussion 122-118, 281-197
    • (2003) Novartis Found Symp , vol.251 , pp. 112-122
    • Bauman, M.L.1    Kemper, T.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.