Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 43, 2010, Pages 18569-18574

  Faust, Thomas W ^a   Chang, Eric H ^a   Kowal, Czeslawa ^b   Berlin, RoseAnn ^a   Gazaryan, Irina G ^a   Bertini, Eva ^b   Zhang, Jie ^b   Sanchez Guerrero, Jorge ^c   Fragoso Loyo, Hilda E ^c   Volpe, Bruce T ^a   Diamond, Betty ^b   Huerta, Patricio T ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

Autoimmunity; Mitochondrial stress; Neuropsychiatric lupus; NMDA receptor

Indexed keywords

AUTOANTIBODY; DNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SYNAPSE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN FUNCTION; COGNITIVE DEFECT; CONCENTRATION (PARAMETERS); EMOTIONAL DISORDER; EXCITOTOXICITY; FEMALE; MITOCHONDRION; MOUSE; NEUROPSYCHIATRY; NEUROTOXICITY; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; AUTOANTIBODIES; BRAIN; CROSS REACTIONS; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS VASCULITIS, CENTRAL NERVOUS SYSTEM; MICE; MICE, INBRED BALB C; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MODELS, IMMUNOLOGICAL; MODELS, NEUROLOGICAL; NEUROTOXINS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 78649839312     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1006980107     Document Type: Article

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