Development of a fluid bed granulation design space using critical quality attribute weighted tolerance intervals

Journal of Pharmaceutical Sciences

Volumn 101, Issue 8, 2012, Pages 2917-2929

  Zacour, Brian M ^a   Drennen, James K ^a   Anderson, Carl A ^a  

^a DUQUESNE UNIVERSITY   (United States)

Author keywords

Design space; Fluid bed processing; Multivariate modeling; Process analytical technology; Quality by design

Indexed keywords

EXCIPIENT; GRANULAC 70; HYDROXYPROPYLMETHYLCELLULOSE; LACTOSE; MICROCRYSTALLINE CELLULOSE; UNCLASSIFIED DRUG;

ARTICLE; AUTOMATION; DRUG FORMULATION; DRUG QUALITY; FLUID BED GRANULATION; MATHEMATICAL MODEL; PARTICLE SIZE; PROCESS TECHNOLOGY; QUALITY CONTROL; WETTABILITY;

EID: 84862837246     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23185     Document Type: Article

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