Targeting mitochondria by α-tocopheryl succinate kills neuroblastoma cells irrespective of MycN oncogene expression

Cellular and Molecular Life Sciences

Volumn 69, Issue 12, 2012, Pages 2091-2099

  Kruspig, Björn ^a   Nilchian, Azadeh ^a   Bejarano, Ignacio ^b   Orrenius, Sten ^a   Zhivotovsky, Boris ^a,c   Gogvadze, Vladimir ^a,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF EXTREMADURA   (Spain)

^c MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Apoptosis; Calcium; Mitochondria; MycN

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; BUFFER; CALCIUM ION; CISPLATIN; DOXYCYCLINE; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; GENE EXPRESSION; GENE OVEREXPRESSION; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; NEUROBLASTOMA CELL; NONHUMAN; ONCOGENE; ONCOGENE MYCN; TUMOR CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MITOCHONDRIA; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; TOCOPHEROLS;

TOSCANA VIRUS;

EID: 84862835202     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-0918-4     Document Type: Article

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