-
1
-
-
33646181088
-
How TCRs bind MHCs, peptides, and coreceptors
-
Rudolph MG, Stanfield RL, Wilson IA,. How TCRs bind MHCs, peptides, and coreceptors. Annu Rev Immunol 2006; 24: 419-466.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 419-466
-
-
Rudolph, M.G.1
Stanfield, R.L.2
Wilson, I.A.3
-
2
-
-
58849158737
-
Different T cell receptor signals determine CD8 +memory versus effector development
-
Teixeiro E, Daniels MA, Hamilton SE, et al,. Different T cell receptor signals determine CD8 +memory versus effector development. Science 2009; 323: 502-505.
-
(2009)
Science
, vol.323
, pp. 502-505
-
-
Teixeiro, E.1
Daniels, M.A.2
Hamilton, S.E.3
-
3
-
-
77249114784
-
TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity
-
Huppa JB, Axmann M, Mortelmaier MA, et al,. TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. Nature 2010; 463: 963-967.
-
(2010)
Nature
, vol.463
, pp. 963-967
-
-
Huppa, J.B.1
Axmann, M.2
Mortelmaier, M.A.3
-
4
-
-
62249131518
-
Complete but curtailed T-cell response to very low-affinity antigen
-
Zehn D, Lee SY, Bevan MJ,. Complete but curtailed T-cell response to very low-affinity antigen. Nature 2009; 458: 211-214.
-
(2009)
Nature
, vol.458
, pp. 211-214
-
-
Zehn, D.1
Lee, S.Y.2
Bevan, M.J.3
-
5
-
-
65249101637
-
The promise and potential pitfalls of chimeric antigen receptors
-
Sadelain M, Brentjens R, Riviere I,. The promise and potential pitfalls of chimeric antigen receptors. Curr Opin Immunol 2009; 21: 215-223.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 215-223
-
-
Sadelain, M.1
Brentjens, R.2
Riviere, I.3
-
6
-
-
0034789792
-
Antigen-specific immunomodulation via altered peptide ligands
-
Bielekova B, Martin R,. Antigen-specific immunomodulation via altered peptide ligands. J Mol Med 2001; 79: 552-565.
-
(2001)
J Mol Med
, vol.79
, pp. 552-565
-
-
Bielekova, B.1
Martin, R.2
-
8
-
-
77951529848
-
Therapeutic antibodies for autoimmunity and inflammation
-
Chan AC, Carter PJ,. Therapeutic antibodies for autoimmunity and inflammation. Nat Rev Immunol 2010; 10: 301-316.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 301-316
-
-
Chan, A.C.1
Carter, P.J.2
-
9
-
-
2442667813
-
Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3
-
Kjer-Nielsen L, Dunstone MA, Kostenko L, et al,. Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3. Proc Natl Acad Sci U S A 2004; 101: 7675-7680.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7675-7680
-
-
Kjer-Nielsen, L.1
Dunstone, M.A.2
Kostenko, L.3
-
10
-
-
0025947144
-
A conformational epitope expressed upon association of CD3-epsilon with either CD3-delta or CD3-gamma is the main target for recognition by anti-CD3 monoclonal antibodies
-
Salmeron A, Sanchez-Madrid F, Ursa MA, Fresno M, Alarcon B,. A conformational epitope expressed upon association of CD3-epsilon with either CD3-delta or CD3-gamma is the main target for recognition by anti-CD3 monoclonal antibodies. J Immunol 1991; 147: 3047-3052.
-
(1991)
J Immunol
, vol.147
, pp. 3047-3052
-
-
Salmeron, A.1
Sanchez-Madrid, F.2
Ursa, M.A.3
Fresno, M.4
Alarcon, B.5
-
11
-
-
0026071251
-
OKT3 first-dose reaction: Association with T cell subsets and cytokine release
-
Gaston RS, Deierhoi MH, Patterson T, et al,. OKT3 first-dose reaction: Association with T cell subsets and cytokine release. Kidney Int 1991; 39: 141-148.
-
(1991)
Kidney Int
, vol.39
, pp. 141-148
-
-
Gaston, R.S.1
Deierhoi, M.H.2
Patterson, T.3
-
12
-
-
34547230077
-
CD3-specific antibodies: A portal to the treatment of autoimmunity
-
Chatenoud L, Bluestone JA,. CD3-specific antibodies: A portal to the treatment of autoimmunity. Nat Rev Immunol 2007; 7: 622-632.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 622-632
-
-
Chatenoud, L.1
Bluestone, J.A.2
-
13
-
-
78649667340
-
New generation CD3 monoclonal antibodies: Are we ready to have them back in clinical transplantation?
-
You S, Chatenoud L,. New generation CD3 monoclonal antibodies: Are we ready to have them back in clinical transplantation? Curr Opin Organ Transplant 2010; 15: 720-724.
-
(2010)
Curr Opin Organ Transplant
, vol.15
, pp. 720-724
-
-
You, S.1
Chatenoud, L.2
-
14
-
-
80051471700
-
Et al. Teplizumab for treatment of type 1 diabetes (Protege study): 1-Year results from a randomised, placebo-controlled trial
-
Sherry N, Hagopian W, Ludvigsson J, et al. Teplizumab for treatment of type 1 diabetes (Protege study): 1-Year results from a randomised, placebo-controlled trial. Lancet 2011; 378: 487-97.
-
(2011)
Lancet
, vol.378
, pp. 487-497
-
-
Sherry, N.1
Hagopian, W.2
Ludvigsson, J.3
-
15
-
-
0028287480
-
Clinical evaluation of induction immunosuppression with a murine IgG2b monoclonal antibody (BMA 031) directed toward the human alpha/beta-T cell receptor
-
Knight RJ, Kurrle R, McClain J, et al,. Clinical evaluation of induction immunosuppression with a murine IgG2b monoclonal antibody (BMA 031) directed toward the human alpha/beta-T cell receptor. Transplantation 1994; 57: 1581-1588.
-
(1994)
Transplantation
, vol.57
, pp. 1581-1588
-
-
Knight, R.J.1
Kurrle, R.2
McClain, J.3
-
16
-
-
77953658217
-
T10B9 monoclonal antibody: A short-acting nonstimulating monoclonal antibody that spares gammadelta T-cells and treats and prevents cellular rejection
-
Waid TH, Thompson JS, Siemionow M, Brown SA,. T10B9 monoclonal antibody: A short-acting nonstimulating monoclonal antibody that spares gammadelta T-cells and treats and prevents cellular rejection. Drug Des Devel Ther 2009; 3: 205-212.
-
(2009)
Drug des Devel Ther
, vol.3
, pp. 205-212
-
-
Waid, T.H.1
Thompson, J.S.2
Siemionow, M.3
Brown, S.A.4
-
17
-
-
0030932033
-
Induction immunotherapy in heart transplantation with T10B9.1A-31: A phase i study
-
Waid TH, Thompson JS, McKeown JW, Brown SA, Sekela ME,. Induction immunotherapy in heart transplantation with T10B9.1A-31: A phase I study. J Heart Lung Transplant 1997; 16: 913-916.
-
(1997)
J Heart Lung Transplant
, vol.16
, pp. 913-916
-
-
Waid, T.H.1
Thompson, J.S.2
McKeown, J.W.3
Brown, S.A.4
Sekela, M.E.5
-
19
-
-
85047700163
-
Comparison of in vivo efficacy and mechanism of action of antimurine monoclonal antibodies directed against TCR alpha beta (H57-597) and CD3 (145-2C11)
-
Henrickson M, Reid J, Bellet JS, Sawchuk SS, Hirsch R,. Comparison of in vivo efficacy and mechanism of action of antimurine monoclonal antibodies directed against TCR alpha beta (H57-597) and CD3 (145-2C11). Transplantation 1995; 60: 828-835.
-
(1995)
Transplantation
, vol.60
, pp. 828-835
-
-
Henrickson, M.1
Reid, J.2
Bellet, J.S.3
Sawchuk, S.S.4
Hirsch, R.5
-
20
-
-
0029954330
-
Treatment of donor mice with an alpha beta T-cell receptor monoclonal antibody induces prolonged T-cell nonresponsiveness and effectively prevents lethal graft-versus-host disease in murine recipients of major histocompatibility complex (MHC)-matched and MHC-mismatched donor marrow grafts
-
Drobyski WR, Majewski D,. Treatment of donor mice with an alpha beta T-cell receptor monoclonal antibody induces prolonged T-cell nonresponsiveness and effectively prevents lethal graft-versus-host disease in murine recipients of major histocompatibility complex (MHC)-matched and MHC-mismatched donor marrow grafts. Blood 1996; 87: 5355-5369.
-
(1996)
Blood
, vol.87
, pp. 5355-5369
-
-
Drobyski, W.R.1
Majewski, D.2
-
21
-
-
0028336921
-
Synergistic immunosuppressive actions of cyclosporine with a mouse anti-rat alpha/beta-T cell receptor monoclonal antibody
-
Knight RJ, Kurrle R, Stepkowski S, Serino F, Chou TC, Kahan BD,. Synergistic immunosuppressive actions of cyclosporine with a mouse anti-rat alpha/beta-T cell receptor monoclonal antibody. Transplantation 1994; 57: 1544-1548.
-
(1994)
Transplantation
, vol.57
, pp. 1544-1548
-
-
Knight, R.J.1
Kurrle, R.2
Stepkowski, S.3
Serino, F.4
Chou, T.C.5
Kahan, B.D.6
-
22
-
-
78650842081
-
Induction immunosuppression improves long-term graft and patient outcome in organ transplantation: An analysis of United Network for Organ Sharing registry data
-
Cai J, Terasaki PI,. Induction immunosuppression improves long-term graft and patient outcome in organ transplantation: an analysis of United Network for Organ Sharing registry data. Transplantation 2010; 90: 1511-1515.
-
(2010)
Transplantation
, vol.90
, pp. 1511-1515
-
-
Cai, J.1
Terasaki, P.I.2
-
23
-
-
0015866545
-
Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejection
-
Corry RJ, Winn HJ, Russell PS,. Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejection. Transplantation 1973; 16: 343-350.
-
(1973)
Transplantation
, vol.16
, pp. 343-350
-
-
Corry, R.J.1
Winn, H.J.2
Russell, P.S.3
-
24
-
-
0028026941
-
Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats
-
Ferraresso M, Tian L, Ghobrial R, Stepkowski SM, Kahan BD,. Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats. J Immunol 1994; 153: 3307-3318.
-
(1994)
J Immunol
, vol.153
, pp. 3307-3318
-
-
Ferraresso, M.1
Tian, L.2
Ghobrial, R.3
Stepkowski, S.M.4
Kahan, B.D.5
-
26
-
-
0025226018
-
Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice
-
Strasser A, Harris AW, Vaux DL, et al,. Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice. Curr Top Microbiol Immunol 1990; 166: 175-181.
-
(1990)
Curr Top Microbiol Immunol
, vol.166
, pp. 175-181
-
-
Strasser, A.1
Harris, A.W.2
Vaux, D.L.3
-
27
-
-
11144355749
-
Homeostatic proliferation is a barrier to transplantation tolerance
-
Wu Z, Bensinger SJ, Zhang J, et al,. Homeostatic proliferation is a barrier to transplantation tolerance. Nat Med 2004; 10: 87-92.
-
(2004)
Nat Med
, vol.10
, pp. 87-92
-
-
Wu, Z.1
Bensinger, S.J.2
Zhang, J.3
-
28
-
-
78650899002
-
Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression
-
Lo DJ, Weaver TA, Stempora L, et al,. Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression. Am J Transplant 2011; 11: 22-33.
-
(2011)
Am J Transplant
, vol.11
, pp. 22-33
-
-
Lo, D.J.1
Weaver, T.A.2
Stempora, L.3
-
29
-
-
77956200555
-
"Default" generation of neonatal regulatory T cells
-
Wang G, Miyahara Y, Guo Z, Khattar M, Stepkowski SM, Chen W,. "Default" generation of neonatal regulatory T cells. J Immunol 2010; 185: 71-78.
-
(2010)
J Immunol
, vol.185
, pp. 71-78
-
-
Wang, G.1
Miyahara, Y.2
Guo, Z.3
Khattar, M.4
Stepkowski, S.M.5
Chen, W.6
-
30
-
-
77955012740
-
IL-2-deprivation and TGF-beta are two non-redundant suppressor mechanisms of CD4+CD25+ regulatory T cell which jointly restrain CD4+CD25- cell activation
-
Wang G, Khattar M, Guo Z, et al,. IL-2-deprivation and TGF-beta are two non-redundant suppressor mechanisms of CD4+CD25+ regulatory T cell which jointly restrain CD4+CD25- cell activation. Immunol Lett 2010; 132: 61-68.
-
(2010)
Immunol Lett
, vol.132
, pp. 61-68
-
-
Wang, G.1
Khattar, M.2
Guo, Z.3
-
31
-
-
77249166530
-
IL-7, but not thymic stromal lymphopoietin (TSLP), during priming enhances the generation of memory CD4+ T cells
-
Guo Z, Wang G, Miyahara Y, et al,. IL-7, but not thymic stromal lymphopoietin (TSLP), during priming enhances the generation of memory CD4+ T cells. Immunol Lett 2010; 128: 116-123.
-
(2010)
Immunol Lett
, vol.128
, pp. 116-123
-
-
Guo, Z.1
Wang, G.2
Miyahara, Y.3
-
32
-
-
0141796312
-
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
Belghith M, Bluestone JA, Barriot S, Megret J, Bach JF, Chatenoud L,. TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 2003; 9: 1202-1208.
-
(2003)
Nat Med
, vol.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.A.2
Barriot, S.3
Megret, J.4
Bach, J.F.5
Chatenoud, L.6
-
33
-
-
33845713001
-
Monoclonal antibody against T-cell receptor alphabeta induces self-tolerance in chronic experimental autoimmune encephalomyelitis
-
Lavasani S, Dzhambazov B, Andersson M,. Monoclonal antibody against T-cell receptor alphabeta induces self-tolerance in chronic experimental autoimmune encephalomyelitis. Scand J Immunol 2007; 65: 39-47.
-
(2007)
Scand J Immunol
, vol.65
, pp. 39-47
-
-
Lavasani, S.1
Dzhambazov, B.2
Andersson, M.3
-
34
-
-
0026608474
-
Prevention of collagen induced arthritis in mice by treatment with an antibody directed against the T cell receptor alpha beta framework
-
Moder KG, Luthra HS, Kubo R, Griffiths M, David CS,. Prevention of collagen induced arthritis in mice by treatment with an antibody directed against the T cell receptor alpha beta framework. Autoimmunity 1992; 11: 219-224.
-
(1992)
Autoimmunity
, vol.11
, pp. 219-224
-
-
Moder, K.G.1
Luthra, H.S.2
Kubo, R.3
Griffiths, M.4
David, C.S.5
|