Regulated hepatic reperfusion mitigates ischemia-reperfusion injury and improves survival after prolonged liver warm ischemia: A pilot study on a novel concept of organ resuscitation in a large animal model

Journal of the American College of Surgeons

Volumn 214, Issue 4, 2012, Pages 505-515

  Hong, Johnny C ^a   Koroleff, Dimitri ^a   Xia, Victor ^a   Chang, Chun Ming ^a   Duarte, Sergio M ^a   Xu, Junming ^a   Lassman, Charles ^a,b   Kupiec Weglinski, Jerzy ^a   Coito, Ana J ^a   Busuttil, Ronald W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

IRI; ischemia and reperfusion injury; liver transplantation; LT; mean pulmonary arterial pressure; mPAP; MPO; myeloperoxidase; regulated hepatic reperfusion; RHR; warm ischemia; WI

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; HEMODYNAMICS; HISTOPATHOLOGY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER FUNCTION; LIVER GRAFT; LIVER ISCHEMIA; LIVER NECROSIS; LIVER PERFUSION; LIVER SURGERY; LIVER TRANSPLANTATION; NONHUMAN; PERFUSION PRESSURE; PH; PILOT STUDY; PORTAL VEIN BLOOD; PRIORITY JOURNAL; REGULATORY MECHANISM; REPERFUSION INJURY; SURVIVAL; SWINE; TEMPERATURE;

ANIMALS; DISEASE MODELS, ANIMAL; KAPLAN-MEIER ESTIMATE; LIVER; LIVER FUNCTION TESTS; LIVER TRANSPLANTATION; PILOT PROJECTS; REPERFUSION; REPERFUSION INJURY; RESUSCITATION; SURVIVAL RATE; SWINE; TIME FACTORS; WARM ISCHEMIA;

EID: 84862831136     PISSN: 10727515     EISSN: 18791190     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2011.12.010     Document Type: Article

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