Low-level ganglionated plexus stimulation facilitates atrial fibrillation: In vivo and in vitro studies

Autonomic Neuroscience: Basic and Clinical

Volumn 168, Issue 1-2, 2012, Pages 58-65

  Wu, Liu ^a   Lu, Zhibing ^a   Jiang, Hong ^a   He, Bo ^a   He, Wenbo ^a   Cui, Bo ^a   Hu, Xiaorong ^a   Huang, Congxin ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Atrial fibrillation; Autonomic nervous system; Ganglionated plexus

Indexed keywords

ACETYLCHOLINE; CALCIUM CHANNEL L TYPE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; GANGLION; HEART ATRIUM; HEART ATRIUM FIBRILLATION; HEART MUSCLE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY VEIN; TRANSCRIPTION REGULATION; UPREGULATION;

ACETYLCHOLINE; ANIMALS; ATRIAL FIBRILLATION; BLOTTING, WESTERN; CALCIUM CHANNELS, L-TYPE; DOGS; ELECTRIC STIMULATION; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; ELECTROPHYSIOLOGICAL PHENOMENA; EVOKED POTENTIALS; GANGLIA, AUTONOMIC; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HEART; HEART ATRIA; MUSCARINIC ANTAGONISTS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, MUSCARINIC; REFRACTORY PERIOD, ELECTROPHYSIOLOGICAL; RNA; RNA, MESSENGER;

EID: 84862830149     PISSN: 15660702     EISSN: 18727484     Source Type: Journal    
DOI: 10.1016/j.autneu.2012.02.001     Document Type: Article

References (30)

1. Brundel B.J., van Gelder I.C., Henning R.H., Tuinenburg A.E., Deelman L.E., Tieleman R.G., Grandjean J.G., van Gilst W.H., Crijns H.J. Gene expression of proteins influencing the calcium homeostasis in patients with persistent and paroxysmal atrial fibrillation. Cardiovasc. Res. 1999, 42(2):443-454.
2. Brundel B.J., Van Gelder I.C., Henning R.H., Tuinenburg A.E., Wietses M., Grandjean J.G., Wilde A.A., Van Gilst W.H., Crijns H.J. Alterations in potassium channel gene expression in atria of patients with persistent and paroxysmal atrial fibrillation: differential regulation of protein and mRNA levels for K+ channels. J. Am. Coll. Cardiol. 2001, 37(3):926-932.
3. Chen J., Jiang H., Xu L., Zhu L.H., Wang L., Wen H.Z., Hu X.R. Dysregulation of CREB binding protein triggers thrombin-induced proliferation of vascular smooth muscle cells. Mol. Cell. Biochem. 2008, 315:123-130.
4. Chevalier P., Tabib A., Meyronnet D., Chalabreysse L., Restier L., Ludman V., Aliès A., Adeleine P., Thivolet F., Burri H., Loire R., François L., Fanton L. Quantitative study of nerves of the human left atrium. Hear. Rhythm. 2005, 2:518-522.
5. Coumel P. Paroxysmal atrial fibrillation: a disorder of autonomic tone. Eur. Hear. J. 1994, 15:9-16.
6. Hou Y., Scherlag B.J., Lin J., Zhang Y., Lu Z., Truong K., Patterson E., Lazzara R., Jackman W.M., Po S.S. Ganglionated plexi modulate extrinsic cardiac autonomic nerve input: effects on sinus rate, atrioventricular conduction, refractoriness, and inducibility of atrial fibrillation. J. Am. Coll. Cardiol. 2007, 50:61-68.
7. Li S., Scherlag B.J., Yu L., Sheng X., Zhang Y., Ali R., Dong Y., Ghias M., Po S.S. Low-level vagosympathetic stimulation: a paradox and potential new modality for the treatment of focal atrial fibrillation. Circ. Arrhythm. Electrophysiol. 2009, 2:645-651.
8. Lu Z., Scherlag B.J., Lin J., Niu G., Fung K.M., Zhao L., Ghias M., Jackman W.M., Lazzara R., Jiang H., Po S.S. Atrial fibrillation begets atrial fibrillation: autonomic mechanism for atrial electrical remodeling induced by short-term rapid atrial pacing. Circ. Arrhythm. Electrophysiol. 2008, 1:184-192.
9. Lu Z., Scherlag B.J., Lin J., Niu G., Ghias M., Jackman W.M., Lazzara R., Jiang H., Po S.S. Autonomic mechanism for complex fractionated atrial electrograms: evidence by fast fourier transform analysis. J. Cardiovasc. Electrophysiol. 2008, 19:835-842.
10. Lu Z., Scherlag B.J., Lin J., Yu L., Guo J.H., Niu G., Jackman W.M., Lazzara R., Jiang H., Po S.S. Autonomic mechanism for initiation of rapid firing from atria and pulmonary veins: evidence by ablation of ganglionated plexi. Cardiovasc. Res. 2009, 84:245-252.
11. Lu Z., Scherlag B.J., Niu G., Lin J., Fung K.M., Zhao L., Yu L., Jackman W.M., Lazzara R., Jiang H., Po S.S. Functional properties of the superior vena cava (SVC)-aorta ganglionated plexus: evidence suggesting an autonomic basis for rapid SVC firing. J. Cardiovasc. Electrophysiol. 2010, 21:1392-1399.
12. Maisel W.H. Autonomic modulation preceding the onset of atrial fibrillation. J. Am. Coll. Cardiol. 2003, 42:1269-1270.
13. Pappone C., Santinelli V., Manguso F., Vicedomini G., Gugliotta F., Augello G., Mazzone P., Tortoriello V., Landoni G., Zangrillo A., Lang C., Tomita T., Mesas C., Mastella E., Alfieri O. Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation. Circulation 2004, 109:327-334.
14. Pauza D.H., Skripka V., Pauziene N., Stropus R. Morphology, distribution and variability of the epicardiac neural ganglionated subplexuses in the human heart. Anat. Rec. 2000, 259:353-382.
15. Po S.S., Nakagawa H., Jackman W.M. Localization of left atrial ganglionated plexi in patients with atrial fibrillation. J. Cardiovasc. Electrophysiol. 2009, 20:1186-1189.
16. Pokushalov E., Romanov A., Artyomenko S., Turov A., Shirokova N., Katritsis D.G. Left atrial ablation at the anatomic areas of ganglionated plexi for paroxysmal atrial fibrillation. Pacing Clin. Electrophysiol. 2010, 33:1231-1238.
17. Rana O.R., Saygili E., Gemein C., Zink M.D., Buhr A., Saygili E., Mischke K., Nolte K.W., Weis J., Weber C., Marx N., Schauerte P. Chronic electrical neuronal stimulation increases cardiac parasympathetic tone by eliciting neurotrophic effects. Circ. Res. 2011, 108(10):1209-1219.
18. Ringdahl E.N. Vagally mediated atrial fibrillation in a young man. Arch. Fam. Med. 2000, 9:389-390.
19. Schauerte P., Scherlag B.J., Pitha J., Scherlag M.A., Reynolds D., Lazzara R., Jackman W.M. Catheter ablation of cardiac autonomic nerves for prevention of vagal atrial fibrillation. Circulation 2000, 102:2774-2780.
20. Scherlag B.J., Yamanashi W., Patel U., Lazzara R., Jackman W.M. Autonomically induced conversion of pulmonary vein focal firing into atrial fibrillation. J. Am. Coll. Cardiol. 2005, 4:1878-1886.
21. Van den Berg M.P., Haaksma J., Brouwer J., Tieleman R.G., Mulder G., Crijns H.J. Heart rate variability in patients with atrial fibrillation is related to vagal tone. Circulation 1997, 96:1209-1216.
22. Van Gelder I.C., Brundel B.J., Henning R.H., Tuinenburg A.E., Tieleman R.G., Deelman L., Grandjean J.G., De Kam P.J., Van Gilst W.H., Crijns H.J. Alterations in gene expression of proteins involved in the calcium handling in patients with atrial fibrillation. J. Cardiovasc. Electrophysiol. 1999, 10(4):552-560.
23. K,ACh channels in patients with chronic atrial fibrillation. Cardiovasc. Res. 2007, 74(3):426-437.
24. Yamada M., Inanobe A., Kurachi Y. G protein regulation of potassium ion channels. Pharmacol. Rev. 1998, 50:723-757.
25. Yeh Y.H., Qi X., Shiroshita-Takeshita A., Liu J., Maguy A., Chartier D., Hebert T., Wang Z., Nattel S. Atrial tachycardia induces remodeling of muscarinic receptors and their coupled potassium currents in canine left atrial and pulmonary vein cardiomyocytes. Br. J. Pharmacol. 2007, 152(7):1021-1032.
26. Yu L., Scherlag B.J., Li S., Sheng X., Lu Z., Nakagawa H., Zhang Y., Jackman W.M., Lazzara R., Jiang H., Po S.S. Low-level vagosympathetic nerve stimulation inhibits atrial fibrillation inducibility: direct evidence by neural recordings from intrinsic cardiac Ganglia. J. Cardiovasc. Electrophysiol. 2011, 22:455-463.
27. Yue L., Feng J., Li G.R., Nattel S. Transient outward and delayed rectifier currents in canine atrium: properties and role of isolation methods. Am. J. Physiol. 1996, 270:2157-2168.
28. Yue L., Melnyk P., Gaspo R., Wang Z., Nattel S. Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation. Circ. Res. 1999, 84(7):776-784.
29. KACh after vagal stimulation plus rapid pacing in the pulmonary vein. Rev. Esp. Cardiol. 2009, 62:742-749.
30. Zhou J., Scherlag B.J., Edwards J., Jackman W.M., Lazzara R., Po S.S. Gradients of atrial refractoriness and inducibility of atrial fibrillation due to stimulation of ganglionated plexi. J. Cardiovasc. Electrophysiol. 2007, 18:83-90.