Estradiol induces partial desensitization of serotonin 1A receptor signaling in the paraventricular nucleus of the hypothalamus and alters expression and interaction of RGSZ1 and Gαz

Neuropharmacology

Volumn 62, Issue 5-6, 2012, Pages 2040-2049

  Creech, R D ^a   Li, Q ^a   Carrasco, G A ^a   Van De Kar, L D ^a   Muma, N A ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

5 HT 1A; Desensitization; Estrogen; Neuroendocrine; Oxytocin; Regulators of G protein signaling proteins

Indexed keywords

CORTICOTROPIN; ESTRADIOL BENZOATE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA Z SUBUNIT; OXYTOCIN; PLACEBO; REGULATOR G PROTEIN SIGNALING PROTEIN Z1; RGS PROTEIN; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; BRAIN REGION; CONTROLLED STUDY; CORTICOTROPIN RELEASE; DEPRESSION; DOSE RESPONSE; DRUG MEGADOSE; DRUG RECEPTOR BINDING; DRUG RESPONSE; DRUG TARGETING; FEMALE; HIPPOCAMPUS; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; NONHUMAN; OXYTOCIN RELEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; TISSUE DISTRIBUTION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; FEMALE; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTPASE-ACTIVATING PROTEINS; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; OXYTOCIN; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN RECEPTOR AGONISTS; SIGNAL TRANSDUCTION;

EID: 84862829095     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.01.001     Document Type: Article

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