DACH1 regulates cell cycle progression of myeloid cells through the control of cyclin D, Cdk 4/6 and p21 Cip1

Biochemical and Biophysical Research Communications

Volumn 420, Issue 1, 2012, Pages 91-95

  Lee, Jae Woong ^a   Kim, Hyeng Soo ^a   Kim, Seonggon ^a   Hwang, Junmo ^a   Kim, Young Hun ^a   Lim, Ga Young ^a   Sohn, Wern Joo ^a   Yoon, Suk Ran ^b   Kim, Jae Young ^a   Park, Tae Sung ^c   Park, Kwon Moo ^d   Ryoo, Zae Young ^a   Lee, Sanggyu ^a  

^a Kyungpook National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Kyung Hee University Hospital   (South Korea)

^d Kyungpook National University School of Medicine   (South Korea)

Author keywords

CCND; DACH1; MLL AF9; Myeloid leukemia; P21 Cip1

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN D; CYCLIN D1; CYCLIN D3; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DACH1 PROTEIN; KRUPPEL LIKE FACTOR 4; OCTAMER TRANSCRIPTION FACTOR 4; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL LEVEL; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; UPREGULATION;

ANIMALS; CELL CYCLE; CELLS, CULTURED; CYCLIN D; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P21; EYE PROTEINS; GENE KNOCKDOWN TECHNIQUES; HL-60 CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MYELOID CELLS; OCTAMER TRANSCRIPTION FACTOR-3; SOXB1 TRANSCRIPTION FACTORS; STEM CELLS; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC; UP-REGULATION;

EID: 84862828431     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.02.120     Document Type: Article

References (22)

1. Zolota V., Sirinian C., Melachrinou M., Symeonidis A., Bonikos D.S. Expression of the regulatory cell cycle proteins p21, p27, p14, p16, p53, mdm2, and cyclin E in bone marrow biopsies with acute myeloid leukemia. Correlation with patients' survival. Pathol. Res. Pract. 2007, 203:199-207.
2. Liu J.H., Yen C.C., Lin Y.C., Gau J.P., Yang M.H., Chao T.C., Hsiao L.T., Wang W.S., Tsai Y.C., Chen P.M. Overexpression of cyclin D1 in accelerated-phase chronic myeloid leukemia. Leuk. Lymphoma 2004, 45:2419-2425.
3. Rodriguez S., Khabir A., Keryer C., Perrot C., Drira M., Ghorbel A., Jlidi R., Bernheim A., Valent A., Busson P. Conventional and array-based comparative genomic hybridization analysis of nasopharyngeal carcinomas from the Mediterranean area. Cancer Genet. Cytogenet. 2005, 157:140-147.
4. Haferlach C., Bacher U., Kohlmann A., Schindela S., Alpermann T., Kern W., Schnittger S., Haferlach T. CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia. Haematologica 2011, 96:829-836.
5. Argiropoulos B., Yung E., Xiang P., Lo C.Y., Kuchenbauer F., Palmqvist L., Reindl C., Heuser M., Sekulovic S., Rosten P., Muranyi A., Goh S.L., Featherstone M., Humphries R.K. Linkage of the potent leukemogenic activity of Meis1 to cell-cycle entry and transcriptional regulation of cyclin D3. Blood 2010, 115:4071-4082.
6. Watanabe A., Ogiwara H., Ehata S., Mukasa A., Ishikawa S., Maeda D., Ueki K., Ino Y., Todo T., Yamada Y., Fukayama M., Saito N., Miyazono K., Aburatani H. Homozygously deleted gene DACH1 regulates tumor-initiating activity of glioma cells. Proc. Natl. Acad. Sci. USA 2011, 108:12384-12389.
7. Wu K., Li A., Rao M., Liu M., Dailey V., Yang Y., Di Vizio D., Wang C., Lisanti M.P., Sauter G., Russell R.G., Cvekl A., Pestell R.G. DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth. Mol. Cell Biol. 2006, 26:7116-7129.
8. Wu K., Jiao X., Li Z., Katiyar S., Casimiro M.C., Yang W., Zhang Q., Willmarth N.E., Chepelev I., Crosariol M., Wei Z., Hu J., Zhao K., Pestell R.G. Cell fate determination factor Dachshund reprograms breast cancer stem cell function. J. Biol. Chem. 2011, 286:2132-2142.
9. Lee S., Chen J., Zhou G., Shi R.Z., Bouffard G.G., Kocherginsky M., Ge X., Sun M., Jayathilaka N., Kim Y.C., Emmanuel N., Bohlander S.K., Minden M., Kline J., Ozer O., Larson R.A., LeBeau M.M., Green E.D., Trent J., Karrison T., Liu P.P., Wang S.M., Rowley J.D. Gene expression profiles in acute myeloid leukemia with common translocations using SAGE. Proc. Natl. Acad. Sci. USA 2006, 103:1030-1035.
10. Kim E., Lee J.W., Baek D.C., Lee S.R., Kim M.S., Kim S.H., Kim C.S., Ryoo Z.Y., Kang H.S., Chang K.T. Processing and subcellular localization of ADAM2 in the Macaca fascicularis testis and sperm. Anim. Reprod. Sci. 2010, 117:155-159.
11. Passegue E., Wagers A.J., Giuriato S., Anderson W.C., Weissman I.L. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J. Exp. Med. 2005, 202:1599-1611.
12. D'Angiolella V., Donato V., Vijayakumar S., Saraf A., Florens L., Washburn M.P., Dynlacht B., Pagano M. SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation. Nature 2010, 466:138-142.
13. Matsumoto A., Takeishi S., Kanie T., Susaki E., Onoyama I., Tateishi Y., Nakayama K., Nakayama K.I. P57 is required for quiescence and maintenance of adult hematopoietic stem cells. Cell Stem Cell 2011, 9:262-271.
14. Forsberg E.C., Prohaska S.S., Katzman S., Heffner G.C., Stuart J.M., Weissman I.L. Differential expression of novel potential regulators in hematopoietic stem cells. PLoS Genet. 2005, 1:e28.
15. Pession A., Martino V., Tonelli R., Beltramini C., Locatelli F., Biserni G., Franzoni M., Freccero F., Montemurro L., Pattacini L., Paolucci G. MLL-AF9 oncogene expression affects cell growth but not terminal differentiation and is downregulated during monocyte-macrophage maturation in AML-M5 THP-1 cells. Oncogene 2003, 22:8671-8676.
16. Caslini C., Serna A., Rossi V., Introna M., Biondi A. Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein. Leukemia 2004, 18:1064-1071.
17. Mikulasova Z., Ilencikova D., Slamka T., Durovcikova D. Acute myeloblastic leukaemia with alternations of MLL proto-oncogene protein (11q23/MLL+ AML). Klin. Onkol. 2010, 23:401-407.
18. Chen A., Licht J.D., Wu Y., Hellinger N., Scher W., Waxman S. Retinoic acid is required for and potentiates differentiation of acute promyelocytic leukemia cells by nonretinoid agents. Blood 1994, 84:2122-2129.
19. Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells. J. Biol. Chem. 2005, 280:18120-18129.
20. Heng J.C., Orlov Y.L., Ng H.H. Transcription factors for the modulation of pluripotency and reprogramming. Cold Spring Harb. Symp. Quant. Biol. 2010, 75:237-244.
21. Xu N., Papagiannakopoulos T., Pan G., Thomson J.A., Kosik K.S. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 2009, 137:647-658.
22. Wei Z., Yang Y., Zhang P., Andrianakos R., Hasegawa K., Lyu J., Chen X., Bai G., Liu C., Pera M., Lu W. Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming. Stem Cells 2009, 27:2969-2978.