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Volumn 82, Issue 2, 2012, Pages 83-89

Genetic polymorphisms of FcγRIIa and FcγRIIIa are not predictive of clinical outcomes after cetuximab plus irinotecan chemotherapy in patients with metastatic colorectal cancer

Author keywords

Biomarker; Cetuximab; Colorectal cancer; Fc receptor polymorphism; KRAS mutation

Indexed keywords

CETUXIMAB; FC RECEPTOR; FC RECEPTOR IIA; FC RECEPTOR IIIA; FLUOROURACIL; FOLINIC ACID; GENOMIC DNA; IRINOTECAN; UNCLASSIFIED DRUG;

EID: 84862822870     PISSN: 00302414     EISSN: 14230232     Source Type: Journal    
DOI: 10.1159/000335959     Document Type: Article
Times cited : (23)

References (31)
  • 2
    • 67349152647 scopus 로고    scopus 로고
    • Treatment in advanced colorectal cancer: What, when and how?
    • Chau I, Cunningham D: Treatment in advanced colorectal cancer: what, when and how? Br J Cancer 2009 100 1704-1719.
    • (2009) Br J Cancer , vol.100 , pp. 1704-1719
    • Chau, I.1    Cunningham, D.2
  • 11
    • 17844362179 scopus 로고    scopus 로고
    • Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: A cohort study
    • DOI 10.1016/S1470-2045(05)70102-9, PII S1470204505701029
    • Moroni M, Veronese S, Benvenuti S, Marrapese G, Sartore-Bianchi A, Di Nicolantonio F, Gambacorta M, Siena S, Bardelli A: Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to anti-EGFR treatment in colorectal cancer: a cohort study. Lancet Oncol 2005; 6: 279-286. (Pubitemid 40590264)
    • (2005) Lancet Oncology , vol.6 , Issue.5 , pp. 279-286
    • Moroni, M.1    Veronese, S.2    Benvenuti, S.3    Marrapese, G.4    Sartore-Bianchi, A.5    Di Nicolantonio, F.6    Gambacorta, M.7    Siena, S.8    Bardelli, A.9
  • 14
    • 69749104382 scopus 로고    scopus 로고
    • The role of KRAS mutations in predicting the efficacy of cetuximab-plusirinotecan therapy in irinotecan-refractory Korean metastatic colorectal cancer patients
    • Sohn BS, Kim TW, Lee JL, Ryu MH, Chang HM, Kang YK, Park HS, Na YS, Jang SJ, Kim JC, Lee JS: The role of KRAS mutations in predicting the efficacy of cetuximab-plusirinotecan therapy in irinotecan-refractory Korean metastatic colorectal cancer patients. Oncology 2009; 77: 224-230.
    • (2009) Oncology , vol.77 , pp. 224-230
    • Sohn, B.S.1    Kim, T.W.2    Lee, J.L.3    Ryu, M.H.4    Chang, H.M.5    Kang, Y.K.6    Park, H.S.7    Na, Y.S.8    Jang, S.J.9    Kim, J.C.10    Lee, J.S.11
  • 15
    • 0036500831 scopus 로고    scopus 로고
    • Monoclonal antibodies to target epidermal growth factor receptor-positive tumors a new paradigm for cancer therapy
    • DOI 10.1002/cncr.10372
    • Herbst RS, Shin DM: Monoclonal antibodies to target epidermal growth factor receptorpositive tumors: a new paradigm for cancer therapy. Cancer 2002; 94: 1593-1611. (Pubitemid 34212655)
    • (2002) Cancer , vol.94 , Issue.5 , pp. 1593-1611
    • Herbst, R.S.1    Shin, D.M.2
  • 16
    • 33846564399 scopus 로고    scopus 로고
    • Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma
    • DOI 10.1002/ijc.22370
    • Kawaguchi Y, Kono K, Mimura K, Sugai H, Akaike H, Fujii H: Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma. Int J Cancer 2007; 120: 781-787. (Pubitemid 46175397)
    • (2007) International Journal of Cancer , vol.120 , Issue.4 , pp. 781-787
    • Kawaguchi, Y.1    Kono, K.2    Mimura, K.3    Sugai, H.4    Akaike, H.5    Fujii, H.6
  • 18
    • 35348827319 scopus 로고    scopus 로고
    • Monoclonal antibody mechanisms of action in cancer
    • DOI 10.1007/s12026-007-0073-4
    • Weiner GJ: Monoclonal antibody mechanisms of action in cancer. Immunol Res 2007; 39: 271-278. (Pubitemid 47574893)
    • (2007) Immunologic Research , vol.39 , Issue.1-3 , pp. 271-278
    • Weiner, G.J.1
  • 19
    • 0030611643 scopus 로고    scopus 로고
    • FcγRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell FCγRIIIa, independently of the FCγRIIIa-48L/R/H phenotype
    • Koene HR, Kleijer M, Algra J, Roos D, von dem Borne AE, de Haas M: Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype. Blood 1997; 90: 1109-1114. (Pubitemid 27314146)
    • (1997) Blood , vol.90 , Issue.3 , pp. 1109-1114
    • Koene, H.R.1    Kleijer, M.2    Algra, J.3    Roos, D.4    Von Dem Borne, A.E.G.Kr.5    De Haas, M.6
  • 20
    • 0026492077 scopus 로고
    • On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets Analysis of a functional polymorphism to human IgG 2
    • Parren PW, Warmerdam PA, Boeije LC, Arts J, Westerdaal NA, Vlug A, Capel PJ, Aarden LA, van de Winkel JG: On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2. J Clin Invest 1992; 90: 1537-1546.
    • (1992) J Clin Invest , vol.90 , pp. 1537-1546
    • Parren, P.W.1    Warmerdam, P.A.2    Boeije, L.C.3    Arts, J.4    Westerdaal, N.A.5    Vlug, A.6    Capel, P.J.7    Aarden, L.A.8    Van De Winkel, J.G.9
  • 21
    • 0642373290 scopus 로고    scopus 로고
    • Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma
    • DOI 10.1200/JCO.2003.05.013
    • Weng WK, Levy R: Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma. J Clin Oncol 2003; 21: 3940-3947. (Pubitemid 46606207)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.21 , pp. 3940-3947
    • Weng, W.-K.1    Levy, R.2
  • 26
    • 77955950937 scopus 로고    scopus 로고
    • Immunoglobulin G fragment C receptor polymorphisms and KRAS mutations: Are they useful biomarkers of clinical outcome in advanced colorectal cancer treated with anti-EGFR-based therapy?
    • Paez D, Pare L, Espinosa I, Salazar J, Del Rio E, Barnadas A, Marcuello E, Baiget M: Immunoglobulin G fragment C receptor polymorphisms and KRAS mutations: are they useful biomarkers of clinical outcome in advanced colorectal cancer treated with anti-EGFR-based therapy? Cancer Sci 2010 101 2048-2048.
    • (2010) Cancer Sci , vol.101 , pp. 2048-2053
    • Paez, D.1    Pare, L.2    Espinosa, I.3    Salazar, J.4    Del Rio, E.5    Barnadas, A.6    Marcuello, E.7    Baiget, M.8
  • 28
    • 84862785736 scopus 로고    scopus 로고
    • FCGR2A H131R and FCGR3A V158F polymorphism status in mCRC patients treated with singleagent cetuximab (IMCL 0144 and CA225045) or with second-line irinotecan plus cetuximab (EPIC): A pooled statistical analysis
    • Zhang W, Yang D, Harbison C, Khambata-Ford S, Malone DP, Ning Y, Bohanes PO, Gerger A, Labonte MJ, Benhaim L, El-Khoueiry AB, Iqbal S, Lenz H: FCGR2A H131R and FCGR3A V158F polymorphism status in mCRC patients treated with singleagent cetuximab (IMCL 0144 and CA225045) or with second-line irinotecan plus cetuximab (EPIC): a pooled statistical analysis. J Clin Oncol 2011; 29(15 suppl):e14025.
    • (2011) J Clin Oncol , vol.29 , Issue.15 SUPPL.
    • Zhang, W.1    Yang, D.2    Harbison, C.3    Khambata-Ford, S.4    Malone, D.P.5    Ning, Y.6    Bohanes, P.O.7    Gerger, A.8    Labonte, M.J.9    Benhaim, L.10    El-Khoueiry, A.B.11    Iqbal, S.12    Lenz, H.13
  • 29
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
    • DOI 10.1038/74704
    • Clynes RA, Towers TL, Presta LG, Ravetch JV: Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. Nat Med 2000; 6: 443-446. (Pubitemid 30208162)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 30
    • 79952767715 scopus 로고    scopus 로고
    • Phase i PK/PD study of RO5083945 (GA201), the first glycoengineered anti-EGFR monoclonal antibody (mAb) with optimized antibody dependent cellular cytotoxicity (ADCC)
    • abstract 2522
    • Markman B, Gomez-Roca C, Cervantes-Ruiperez A, Tabernero J: Phase I PK/PD study of RO5083945 (GA201), the first glycoengineered anti-EGFR monoclonal antibody (mAb) with optimized antibody dependent cellular cytotoxicity (ADCC). J Clin Oncol 2010; 28(suppl):abstract 2522.
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL.
    • Markman, B.1    Gomez-Roca, C.2    Cervantes-Ruiperez, A.3    Tabernero, J.4
  • 31
    • 76549085643 scopus 로고    scopus 로고
    • Sym004: A novel synergistic anti-epidermal growth factor receptor antibody mixture with superior anticancer efficacy
    • Pedersen MW, Jacobsen HJ, Koefoed K, Hey A, Pyke C, Haurum JS, Kragh M: Sym004: a novel synergistic anti-epidermal growth factor receptor antibody mixture with superior anticancer efficacy. Cancer Res 2010; 70: 588-597.
    • (2010) Cancer Res , vol.70 , pp. 588-588
    • Pedersen, M.W.1    Jacobsen, H.J.2    Koefoed, K.3    Hey, A.4    Pyke, C.5    Haurum, J.S.6    Kragh, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.