A potential skin substitute constructed with hEGF gene modified HaCaT cells for treatment of burn wounds in a rat model

Burns

Volumn 38, Issue 5, 2012, Pages 702-712

  Hu, Da Hai ^a   Zhang, Zhan Feng ^a   Zhang, Yan Gang ^a   Zhang, Wan Fu ^a   Wang, Hong Tao ^a   Cai, Wei Xia ^a   Bai, Xiao Zhi ^a   Zhu, Hua Yu ^a   Shi, Ji Hong ^a   Tang, Chao Wu ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Epidermal growth factor; Gene transfection; HaCaT cell; Skin equivalent; Tissue engineering

Indexed keywords

BETA1 INTEGRIN; GAMMA UROGASTRONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BURN; CONTROLLED STUDY; EPIDERMIS; FEASIBILITY STUDY; HACAT CELL; IN VIVO STUDY; KERATINOCYTE; NONHUMAN; PROTEIN SECRETION; RAT; SKIN TRANSPLANTATION; SUPERNATANT; TISSUE REGENERATION; WOUND HEALING;

ANIMALS; BURNS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPIDERMAL GROWTH FACTOR; EPIDERMIS; FEASIBILITY STUDIES; GENE TRANSFER TECHNIQUES; HUMANS; KERATINOCYTES; MALE; MICE; MICE, NUDE; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TISSUE ENGINEERING;

EID: 84862820154     PISSN: 03054179     EISSN: 18791409     Source Type: Journal    
DOI: 10.1016/j.burns.2011.12.014     Document Type: Article

References (26)

1. A. Charruyer, and R. Ghadially Stem cells and tissue-engineered skin Skin Pharmacol Physiol 22 2009 55 62
2. W. Lee, J.C. Debasitis, V.K. Lee, J.H. Lee, K. Fischer, and K. Edminster Multi-layered culture of human skin fibroblasts and keratinocytes through three-dimensional freeform fabrication Biomaterials 30 2009 1587 1595
3. P. Boukamp, R.T. Petrussevska, D. Breitkreutz, J. Hornung, A. Markham, and N.E. Fusenig Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line J Cell Biol 106 1988 761 771
4. C.M. Ryle, D. Breitkreutz, H.J. Stark, I.M. Leigh, P.M. Steinert, and D.R. Roop Density dependent modulation of sysnthesis of keratin 1 and 10 in the human keratinocyte line HaCaT and in ras-transfected tumorigenic clones Differentiation 40 1989 42 54
5. D. Breitkreutz, V.M. Schoop, N. Mirancea, M. Baur, H.J. Stark, and N.E. Fusenig Epidermal differentiation and basement membrane formation by HaCaT cells in surface transplants Eur J Cell Biol 75 1998 273 286
6. J. Grabbe, P. Welker, T. Rosenbach, W. Nürnberg, S. Krüger-Krasagakes, and M. Artuc Release of stem cell factor from a human keratinocyte line, HaCaT, is increased in differentiating versus proliferating cells J Invest Dermatol 107 1996 219 224
7. B. Lehmann HaCaT cell line as a model system for vitamin D3 metabolism in human skin J Invest Dermatol 108 1997 78 82
8. V.M. Schoop, N. Mirancea, and N.E. Fusenig Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts J Invest Dermatol 112 1999 343 353
9. K. Kehe, M. Abend, K. Kehe, R. Ridi, R.U. Peter, and D. van Beuningen Tissue engineering with HaCaT cells and a fibroblast cell line Arch Dermatol Res 291 1999 600 605
10. E. Boelsma, M.C. Verhoeven, and M. Ponec Reconstruction of a human skin equivalent using a spontaneously transformed keratinocyte cell line (HaCaT) J Invest Dermatol 112 1999 489 498
11. A.J. Singer, and R.A. Clark Cutaneous wound healing N Engl J Med 341 1999 738 746
12. P. Martin Wound healing - aiming for perfect skin regeneration Science 276 1997 75 81
13. M.M. Santoro, and G. Gaudino Cellular and molecular facets of keratinocyte reepithelization during wound healing Exp Cell Res 304 2005 274 286
14. M.E. Zeigler, S. Krause, S. Karmiol, and J. Varani Growth factor-induced epidermal invasion of the dermis in human skin organ culture: dermal invasion correlated with epithelial cell motility Invasion Metastasis 16 1996 3 10
15. T. Shikiji, M. Minami, T. Inoue, K. Hirose, H. Oura, and S. Arase Keratinocytes can differentiate into eccrine sweat ducts in vitro: involvement of epidermal growth factor and fetal bovine serum J Dermatol Sci 33 2003 141 150
16. R.R. Chen, and D.J. Mooney Polymeric growth factor delivery strategies for tissue engineering Pharm Res 20 2003 1103 1112
17. M. Sokolsky-Papkov, K. Agashi, A. Olaye, K. Shakesheff, and A.J. Domb Polymer carriers for drug delivery in tissue engineering Adv Drug Deliv Rev 59 2007 187 206
18. B.S. Atiyeh, S.N. Hayek, and S.W. Gunn New technologies for burn wound closure and healing - review of the literature Burns 31 2005 944 956
19. S. MacNeil Progress and opportunities for tissue-engineered skin Nature 445 2007 874 880
20. D.M. Supp, and S.T. Boyce Engineered skin substitutes: practices and potentials Clin Dermatol 23 2005 403 412
21. C. Doebis, T. Ritter, C. Brandt, B. Schönberger, H.D. Volk, and M. Seifert Efficient in vitro transduction of epithelial cells and keratinocytes with improved adenoviral gene transfer for the application in skin tissue engineering Transpl Immunol 9 2002 323 329
22. S.T. Andreadis Gene transfer to epidermal stem cells: implications for tissue engineering Expert Opin Biol Ther 4 2004 783 800
23. G. Romano Current development of nonviral-mediated gene transfer Drug News Perspect 20 2007 227 231
24. M. Nishikawa, and M. Hashida Nonviral approaches satisfying various requirements for effective in vivo gene therapy Biol Pharm Bull 25 2002 275 283
25. J. Li, X. Fu, X. Sun, T. Sun, and Z. Sheng The interaction between epidermal growth factor and matrix metalloproteinases induces the development of sweat glands in human fetal skin J Surg Res 106 2002 258 263
26. Z. Sheng, X. Fu, S. Cai, Y. Lei, T. Sun, and X. Bai Regeneration of functional sweat gland-like structures by transplanted differentiated bone marrow mesenchymal stem cells Wound Repair Regen 17 2009 427 435