MR relaxometry of the liver: Significant elevation of T1 relaxation time in patients with liver cirrhosis

European Radiology

Volumn 22, Issue 6, 2012, Pages 1224-1232

  Heye, Tobias ^a   Yang, Schu Ren ^a   Bock, Michael ^b   Brost, Sylvia ^a   Weigand, Kilian ^a   Longerich, Thomas ^c   Kauczor, Hans Ulrich ^a   Hosch, Waldemar ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Liver; Liver cirrhosis; MRI; Quantitative; Relaxation times

Indexed keywords

ADULT; ALGORITHM; ARTICLE; CHILD PUGH CLASSIFICATION; CONTROLLED STUDY; DISEASE CLASSIFICATION; FEMALE; HUMAN; INFORMED CONSENT; LIVER CIRRHOSIS; LIVER PARENCHYMA; MAGNETIC RESONANCE RELAXOMETRY; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROSPECTIVE STUDY; RELAXATION TIME;

ALGORITHMS; FEMALE; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; LIVER CIRRHOSIS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84862819964     PISSN: 09387994     EISSN: 14321084     Source Type: Journal    
DOI: 10.1007/s00330-012-2378-5     Document Type: Article

References (37)

1. World Health Organization (2004) The global burden of disease: 2004 update. WHO Press, Geneva
2. Bolanos-Meade J, Lopez-Arvizu C (2000) Histologic improvement of fibrosis in patients with hepatitis C and sustained response to interferon therapy. Ann Intern Med 133:312 (Pubitemid 30660306)
3. Dixon JB, Bhathal PS, Hughes NR, O'Brien PE (2004) Nonalcoholic fatty liver disease: improvement in liver histological analysis with weight loss. Hepatology 39:1647-1654 (Pubitemid 38702666)
4. Farci P, Roskams T, Chessa L et al (2004) Long-term benefit of interferon alpha therapy of chronic hepatitis D: regression of advanced hepatic fibrosis. Gastroenterology 126:1740-1749 (Pubitemid 38736339)
5. Friedman SL, Bansal MB (2006) Reversal of hepatic fibrosis - fact or fantasy? Hepatology 43:S82-S88
6. Davis GL, Roberts WL (2010) The healthcare burden imposed by liver disease in aging Baby Boomers. Curr Gastroenterol Rep 12:1-6
7. Strauss E (2010) Usefulness of liver biopsy in chronic hepatitis C. Ann Hepatol 9(Suppl):39-42
8. Rockey DC, Caldwell SH, Goodman ZD, Nelson RC, Smith AD (2009) Liver biopsy. Hepatology 49:1017-1044
9. PinzaniM, Rombouts K, Colagrande S (2005) Fibrosis in chronic liver diseases: diagnosis and management. J Hepatol 42(Suppl):S22-S36 (Pubitemid 40364601)
10. Castera L, Pinzani M (2010) Non-invasive assessment of liver fibrosis: are we ready? Lancet 375:1419-1420
11. Castera L, Pinzani M (2010) Biopsy and non-invasive methods for the diagnosis of liver fibrosis: does it take two to tango? Gut 59:861-866
12. Parkes J, Roderick P, Harris S et al (2010) Enhanced liver fibrosis test can predict clinical outcomes in patients with chronic liver disease. Gut 59:1245-1251
13. McPherson S, Stewart SF, Henderson E, Burt AD, Day CP (2010) Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease. Gut 59:1265-1269
14. Vizzutti F, ArenaU, Nobili Vet al (2009) Non-invasive assessment of fibrosis in non-alcoholic fatty liver disease. Ann Hepatol 8:89-94
15. Molleken C, Sitek B, Henkel C et al (2009) Detection of novel biomarkers of liver cirrhosis by proteomic analysis. Hepatology 49:1257-1266
16. Bonekamp S, Kamel I, Solga S, Clark J (2009) Can imaging modalities diagnose and stage hepatic fibrosis and cirrhosis accurately? J Hepatol 50:17-35
17. Hosch W, Bock M, Libicher M et al (2007) MR-relaxometry of myocardial tissue: significant elevation of T1 and T2 relaxation times in cardiac amyloidosis. Invest Radiol 42:636-642 (Pubitemid 47262932)
18. Wang YX, Yuan J, Chu ES et al (2011) T1rho MR imaging is sensitive to evaluate liver fibrosis: an experimental study in a rat biliary duct ligation model. Radiology 259:712-719
19. Lee MJ, Kim MJ, Yoon CS, Han SJ, Park YN (2011) Evaluation of liver fibrosis with T2 relaxation time in infants with cholestasis: comparison with normal controls. Pediatr Radiol 41:350-354
20. Keevil SF, Alstead EM, Dolke G, Brooks AP, Armstrong P, Farthing MJ (1994) Non-invasive assessment of diffuse liver disease by in vivo measurement of proton nuclear magnetic resonance relaxation times at 0.08T. Br J Radiol 67:1083-1087
21. Thomsen C, Christoffersen P, Henriksen O, Juhl E (1990) Prolonged T1 in patients with liver cirrhosis: an in vivo MRI study. Magn Reson Imaging 8:599-604 (Pubitemid 20321976)
22. Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni McWilliams R (1973) Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 60:646-649
23. Bock M, Schulz J, Ueltzhoeffer S, Giesel F, Voth M, Essig M (2008) Intravascular contrast agent T1 shortening: fast T1 relaxometry in a carotid volunteer study. MAGMA 21:363-368
24. Wacker CM, Bock M, Hartlep AW et al (1999) Changes in myocardial oxygenation and perfusion under pharmacological stress with dipyridamole: assessment using T*2 and T1 measurements. Magn Reson Med 41:686-695 (Pubitemid 29205714)
25. Bauer WR, Nadler W, Bock M et al (1999) Theory of coherent and incoherent nuclear spin dephasing in the heart. Phys Rev Lett 83:4215-4218 (Pubitemid 129585307)
26. de Certaines JD, Henriksen O, Spisni A, Cortsen M, Ring PB (1993) In vivo measurements of proton relaxation times in human brain, liver, and skeletal muscle: a multicenter MRI study. Magn Reson Imaging 11:841-850
27. Lerski RA, McRobbie DW, Straughan K, Walker PM, de Certaines JD, Bernard AM (1988) Multi-center trial with protocols and prototype test objects for the assessment of MRI equipment. EEC Concerted Research Project. Magn Reson Imaging 6:201-214
28. Henriksen O, de Certaines JD, Spisni A, Cortsen M, Muller RN, Ring PB (1993) In vivo field dependence of proton relaxation times in human brain, liver and skeletal muscle: a multicenter study. Magn Reson Imaging 11:851-856
29. Bernardino ME, Small W, Goldstein J et al (1983) Multiple NMR T2 relaxation values in human liver tissue. AJR Am J Roentgenol 141:1203-1208 (Pubitemid 14210849)
30. Chamuleau RA, Creyghton JH, De Nie I, Moerland MA, Van der Lende OR, Smidt J (1988) Is the magnetic resonance imaging proton spin-lattice relaxation time a reliable noninvasive parameter of developing liver fibrosis? Hepatology 8:217-221
31. Katsube T, Okada M, Kumano S et al (2011) Estimation of liver function using T1 mapping on Gd-EOB-DTPA-enhanced magnetic resonance imaging. Invest Radiol 46:277-283
32. Castera L, Sebastiani G, Le Bail B, de Ledinghen V, Couzigou P, Alberti A (2010) Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C. J Hepatol 52:191-198
33. Kim SU, Han KH, Ahn SH (2010) Non-invasive assessment of liver fibrosis: time to move from cross-sectional studies to longitudinal ones. J Gastroenterol Hepatol 25:1472-1473
34. Boursier J, Cesbron E, Tropet AL, Pilette C (2009) Comparison and improvement of MELD and Child-Pugh score accuracies for the prediction of 6-month mortality in cirrhotic patients. J Clin Gastroenterol 43:580-585
35. Shaikh S, Ghani H, Memon S, Baloch GH, Jaffery M, Shaikh K (2010) MELD era: is this time to replace the original Child-Pugh score in patients with decompensated cirrhosis of liver. J Coll Physicians Surg Pak 20:432-435
36. Foucher J, Chanteloup E, Vergniol J et al (2006) Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study. Gut 55:403-408 (Pubitemid 43268281)
37. Hashimoto K, Murakami T, Dono K et al (2006) Assessment of the severity of liver disease and fibrotic change: the usefulness of hepatic CT perfusion imaging. Oncol Rep 16:677-683