Upregulation of thromboxane synthase mediates visfatin-induced interleukin-8 expression and angiogenic activity in endothelial cells

Biochemical and Biophysical Research Communications

Volumn 418, Issue 4, 2012, Pages 662-668

  Kim, Su Ryun ^a   Jung, Yun Hoa ^a   Park, Hyun Joo ^a   Kim, Mi Kyoung ^a   Jeong, Joo Won ^b   Jang, Hye Ock ^a   Yun, Il ^a   Bae, Soo Kyung ^a   Bae, Moon Kyoung ^a  

^a Pusan National University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

Author keywords

Angiogenesis; Interleukin 8; Thromboxane A 2; Thromboxane synthase; Vascular endothelial cells; Visfatin

Indexed keywords

INTERLEUKIN 8; INTERLEUKIN 8 RECEPTOR; MESSENGER RNA; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; SMALL INTERFERING RNA; THROMBOXANE A2; THROMBOXANE SYNTHASE; THROMBOXANE SYNTHASE INHIBITOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME SYNTHESIS; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MALE; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

CELL LINE, TUMOR; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; NEOVASCULARIZATION, PHYSIOLOGIC; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; THROMBOXANE A2; THROMBOXANE-A SYNTHASE; UP-REGULATION;

EID: 84862818538     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.01.072     Document Type: Article

References (40)

1. Hug C., Lodish H.F. Medicine. Visfatin: a new adipokine. Science 2005, 307:366-367.
2. Samal B., Sun Y., Stearns G., Xie C., Suggs S., McNiece I. Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. Molecular and Cellular Biology 1994, 14:1431-1437.
3. Revollo J.R., Korner A., Mills K.F., Satoh A., Wang T., Garten A., Dasgupta B., Sasaki Y., Wolberger C., Townsend R.R., Milbrandt J., Kiess W., Imai S. Nampt/PBEF/visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. Cell Metabolism 2007, 6:363-375.
4. Kim S.R., Bae Y.H., Bae S.K., Choi K.S., Yoon K.H., Koo T.H., Jang H.O., Yun I., Kim K.W., Kwon Y.G., Yoo M.A., Bae M.K. Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kappaB activation in endothelial cells. Biochimica et Biophysica Acta 2008, 1783:886-895.
5. Moschen A.R., Kaser A., Enrich B., Mosheimer B., Theurl M., Niederegger H., Tilg H. Visfatin, an adipocytokine with proinflammatory and immunomodulating properties. Journal of Immunology 2007, 178:1748-1758.
6. Kim S.R., Bae S.K., Choi K.S., Park S.Y., Jun H.O., Lee J.Y., Jang H.O., Yun I., Yoon K.H., Kim Y.J., Yoo M.A., Kim K.W., Bae M.K. Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2. Biochemical and Biophysical Research Communications 2007, 357:150-156.
7. Adya R., Tan B.K., Punn A., Chen J., Randeva H.S. Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis. Cardiovascular Research 2008, 78:356-365.
8. Adya R., Tan B.K., Chen J., Randeva H.S. Pre-B cell colony enhancing factor (PBEF)/visfatin induces secretion of MCP-1 in human endothelial cells: role in visfatin-induced angiogenesis. Atherosclerosis 2009, 205:113-119.
9. Bae Y.H., Bae M.K., Kim S.R., Lee J.H., Wee H.J., Bae S.K. Upregulation of fibroblast growth factor-2 by visfatin that promotes endothelial angiogenesis. Biochemical and Biophysical Research Communications 2009, 379:206-211.
10. Kim J.Y., Bae Y.H., Bae M.K., Kim S.R., Park H.J., Wee H.J., Bae S.K. Visfatin through STAT3 activation enhances IL-6 expression that promotes endothelial angiogenesis. Biochimica et Biophysica Acta 2009, 1793:1759-1767.
11. Iniguez M.A., Cacheiro-Llaguno C., Cuesta N., Diaz-Munoz M.D., Fresno M. Prostanoid function and cardiovascular disease. Archives of Physiology and Biochemistry 2008, 114:201-209.
12. Alfranca A., Iniguez M.A., Fresno M., Redondo J.M. Prostanoid signal transduction and gene expression in the endothelium: role in cardiovascular diseases. Cardiovascular Research 2006, 70:446-456.
13. Nakahata N. Thromboxane A2: physiology/pathophysiology, cellular signal transduction and pharmacology. Pharmacology and Therapeutics 2008, 118:18-35.
14. Ishizuka T., Kawakami M., Hidaka T., Matsuki Y., Takamizawa M., Suzuki K., Kurita A., Nakamura H. Stimulation with thromboxane A2 (TXA2) receptor agonist enhances ICAM-1, VCAM-1 or ELAM-1 expression by human vascular endothelial cells. Clinical and Experimental Immunology 1998, 112:464-470.
15. Nie D., Lamberti M., Zacharek A., Li L., Szekeres K., Tang K., Chen Y., Honn K.V. Thromboxane A(2) regulation of endothelial cell migration, angiogenesis, and tumor metastasis. Biochemical and Biophysical Research Communications 2000, 267:245-251.
16. Kim S.R., Bae S.K., Park H.J., Kim M.K., Kim K., Park S.Y., Jang H.O., Yun I., Kim Y.J., Yoo M.A., Bae M.K. Thromboxane A(2) increases endothelial permeability through upregulation of interleukin-8. Biochemical and Biophysical Research Communications 2010, 397:413-419.
17. Yoshimoto A., Kasahara K., Kawashima A., Fujimura M., Nakao S. Characterization of the prostaglandin biosynthetic pathway in non-small cell lung cancer: a comparison with small cell lung cancer and correlation with angiogenesis, angiogenic factors and metastases. Oncology Reports 2005, 13:1049-1057.
18. Nie D., Che M., Zacharek A., Qiao Y., Li L., Li X., Lamberti M., Tang K., Cai Y., Guo Y., Grignon D., Honn K.V. Differential expression of thromboxane synthase in prostate carcinoma: role in tumor cell motility. The American Journal of Pathology 2004, 164:429-439.
19. Cathcart M.C., Gately K., Cummins R., Kay E., O'Byrne K.J., Pidgeon G.P. Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer. Molecular Cancer 2011, 10:25.
20. Cathcart M.C., Reynolds J.V., O'Byrne K.J., Pidgeon G.P. The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer. Biochimica et Biophysica Acta 2010, 1805:153-166.
21. Jaffe E.A., Nachman R.L., Becker C.G., Minick C.R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. Journal of Clinical Investigation 1973, 52:2745-2756.
22. Moussa O., Riker J.M., Klein J., Fraig M., Halushka P.V., Watson D.K. Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents. Oncogene 2008, 27:55-62.
23. Carmeliet P. Angiogenesis in health and disease. Nature Medicine 2003, 9:653-660.
24. Kougias P., Chai H., Lin P.H., Yao Q., Lumsden A.B., Chen C. Effects of adipocyte-derived cytokines on endothelial functions: implication of vascular disease. The Journal of Surgical Research 2005, 126:121-129.
25. Guzik T.J., Mangalat D., Korbut R. Adipocytokines - novel link between inflammation and vascular function?. Journal of Physiology and Pharmacology: an Official Journal of the Polish Physiological Society 2006, 57:505-528.
26. Wang M.T., Honn K.V., Nie D. Cyclooxygenases, prostanoids, and tumor progression. Cancer Metastasis Review 2007, 26:525-534.
27. Norel X. Prostanoid receptors in the human vascular wall. The Scientific World Journal 2007, 7:1359-1374.
28. Muzaffar S., Shukla N., Massey Y., Angelini G.D., Jeremy J.Y. NADPH oxidase 1 mediates upregulation of thromboxane A2 synthase in human vascular smooth muscle cells: inhibition with iloprost. European Journal of Pharmacology 2011, 658:187-192.
29. Watkins G., Douglas-Jones A., Mansel R.E., Jiang W.G. Expression of thromboxane synthase, TBXAS1 and the thromboxane A2 receptor, TBXA2R, in human breast cancer. International Seminars in Surgical Oncology: ISSO 2005, 2:23.
30. Sakai H., Suzuki T., Takahashi Y., Ukai M., Tauchi K., Fujii T., Horikawa N., Minamimura T., Tabuchi Y., Morii M., Tsukada K., Takeguchi N. Upregulation of thromboxane synthase in human colorectal carcinoma and the cancer cell proliferation by thromboxane A2. FEBS Letters 2006, 580:3368-3374.
31. Giese A., Hagel C., Kim E.L., Zapf S., Djawaheri J., Berens M.E., Westphal M. Thromboxane synthase regulates the migratory phenotype of human glioma cells. Neuro-Oncology 1999, 1:3-13.
32. Daniel T.O., Liu H., Morrow J.D., Crews B.C., Marnett L.J. Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis. Cancer Research 1999, 59:4574-4577.
33. Ekambaram P., Lambiv W., Cazzolli R., Ashton A.W., Honn K.V. The thromboxane synthase and receptor signaling pathway in cancer: an emerging paradigm in cancer progression and metastasis. Cancer Metastasis Review 2011, 30:397-408.
34. Moussa O., Yordy J.S., Abol-Enein H., Sinha D., Bissada N.K., Halushka P.V., Ghoneim M.A., Watson D.K. Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer. Cancer Research 2005, 65:11581-11587.
35. Dalamaga M., Karmaniolas K., Papadavid E., Pelekanos N., Sotiropoulos G., Lekka A. Elevated serum visfatin/nicotinamide phosphoribosyl-transferase levels are associated with risk of postmenopausal breast cancer independently from adiponectin, leptin, and anthropometric and metabolic parameters. Menopause 2011, 18:1198-1204.
36. Bae S.K., Kim S.R., Kim J.G., Kim J.Y., Koo T.H., Jang H.O., Yun I., Yoo M.A., Bae M.K. Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1. FEBS Letters 2006, 580:4105-4113.
37. Lee Y.C., Yang Y.H., Su J.H., Chang H.L., Hou M.F., Yuan S.S. High visfatin expression in breast cancer tissue is associated with poor survival. Cancer Epidemiology, Biomarkers and Prevention 2011, 20:1892-1901.
38. Yaekashiwa M., Wang L.H. Transcriptional control of the human thromboxane synthase gene in vivo and in vitro. Journal of Biological Chemistry 2002, 277:22497-22508.
39. Deveaux S., Cohen-Kaminsky S., Shivdasani R.A., Andrews N.C., Filipe A., Kuzniak I., Orkin S.H., Romeo P.H., Mignotte V. p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes. The EMBO Journal 1997, 16:5654-5661.
40. Yaekashiwa M., Wang L.H. Nrf2 regulates thromboxane synthase gene expression in human lung cells. DNA and Cell Biology 2003, 22:479-487.