Oxidized low density lipoprotein-induced senescence of retinal pigment epithelial cells is followed by outer blood-retinal barrier dysfunction

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 5, 2012, Pages 808-814

  Kim, Jin Hyoung ^a   Lee, Sung Joon ^b   Kim, Jeong Hun ^a   Kim, Kyu Won ^c   Yu, Young Suk ^a  

^a Seoul National University Hospital   (South Korea)

^b Korea University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Outer blood retinal barrier; Oxidized low density lipoprotein; Retinal pigment epithelial cell; Senescence

Indexed keywords

APOLIPOPROTEIN E2; BETA CATENIN; CELL PROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEIN CRALBP; PROTEIN RPE 65; PROTEIN ZO1; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN; VISUAL PIGMENT; WNT PROTEIN;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD RETINA BARRIER; CELL DIFFERENTIATION; CELL JUNCTION; CELL MEMBRANE PERMEABILITY; CHOROID CAPILLARY LAYER; INFLAMMATION; MOUSE; NONHUMAN; PATHOGENESIS; PIGMENT EPITHELIUM; PROTEIN EXPRESSION; RETINA MACULA AGE RELATED DEGENERATION; RISK FACTOR; SENESCENCE; TRANSGENIC MOUSE; UPREGULATION; VISUAL IMPAIRMENT;

ANIMALS; APOLIPOPROTEIN E2; BETA CATENIN; BLOOD-RETINAL BARRIER; CELL AGING; CELLS, CULTURED; EPITHELIAL CELLS; HUMANS; LIPOPROTEINS, LDL; MACULAR DEGENERATION; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; PHOSPHOPROTEINS; REACTIVE OXYGEN SPECIES; RETINAL PIGMENT EPITHELIUM; TIGHT JUNCTIONS; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WNT SIGNALING PATHWAY;

MUS MUSCULUS;

EID: 84862813425     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.02.005     Document Type: Article

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