Neuroprotection of VEGF-expression neural stem cells in neonatal cerebral palsy rats

Behavioural Brain Research

Volumn 230, Issue 1, 2012, Pages 108-115

  Zheng, Xiang rong ^a   Zhang, Shan shan ^a   Yin, Fei ^a   Tang, Jie lu ^a   Yang, Yu jia ^a   Wang, Xia ^a   Zhong, Le ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Cerebral palsy; Neural stem cells; Transfection; Vascular endothelial growth factor

Indexed keywords

LENTIVIRUS VECTOR; VASCULOTROPIN;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; BRAIN HYPOXIA; CAROTID ARTERY OBSTRUCTION; CELL SUSPENSION; CEREBRAL PALSY; CONTROLLED STUDY; DRUG EFFECT; EMBRYO; GENE; GENE EXPRESSION; NERVE CELL GROWTH; NEURAL STEM CELL TRANSPLANTATION; NEUROPROTECTION; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORIMOTOR CORTEX; THERAPY EFFECT; TRANSGENE; VEGF GENE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; BRAIN; CAROTID ARTERY DISEASES; CEREBRAL PALSY; DISEASE MODELS, ANIMAL; FEMALE; GENETIC VECTORS; IN SITU NICK-END LABELING; MALE; MENTAL DISORDERS; MICROVESSELS; NEOVASCULARIZATION, PATHOLOGIC; NEUROPROTECTIVE AGENTS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; STEM CELL TRANSPLANTATION; TIME FACTORS; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84862812688     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2012.01.026     Document Type: Article

References (38)

1. Platt M.J., Cans C., Johnson A., Surman G., Topp M., Torrioli M.G., et al. Trends in cerebral palsy among infants of very low birthweight (<1500g) or born prematurely (<32 weeks) in 16 European centres: a database study. Lancet 2007, 369:43-50.
2. Chu Y., Miller J.D., Heistad D.D. Gene therapy for stroke: 2006 overview. Curr Hypertens Rep 2007, 9:19-24.
3. Ho A.L., Keshavarzi S., Levy M.L. Exploitation of genetically modified neural stem cells for neurological disease. Adv Exp Med Biol 2010, 671:74-92.
4. Micci M.A., Pasricha P.J. Neural stem cells for the treatment of disorders of the enteric nervous system: strategies and challenges. Dev Dyn 2007, 236:33-43.
5. López-Bendito G., Arlotta P. Cell replacement therapies for nervous system regeneration. Dev Neurobiol 2011, (May). 10.1002/dneu.20897.
6. Muller F.J., Snyder E.Y., Loring J.F. Gene therapy: can neural stem cells deliver. Nat Rev Neurosci 2006, 7:75-84.
7. Park K.I., Himes B.T., Stieg P.E., Tessler A., Fischer I., Snyder E.Y. Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: evidence from engraftment of neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury. Exp Neurol 2006, 199:179-190.
8. Greenberg D.A., Jin K. From angiogenesis to neuropathology. Nature 2005, 438:954-959.
9. Zheng X., Zhang S., Yang Y., Wang X., Zhong L., Yu X. The targeting expression of the vascular endothelial growth factor gene in endothelial cells regulated by HRE. ppET-1. Sci China C Life Sci 2008, 51:959-965.
10. Chu K., Park K.I., Lee S.T., Kim S.U., Kim M., Roh J.K., et al. Combined treatment of vascular endothelial growth factor and human neural stem cells in experimental focal cerebral ischemia. Neurosci Res 2005, 53:384-390.
11. Zheng X.R., Zhang S.S., Yang Y.J., Wang X., Zhong L., Yu X.H., et al. Adenoviral vector-mediated transduction of VEGF improves neural functional recovery after hypoxia-ischemic brain damage in neonatal rats. Brain Res Bull 2010, 81:372-377.
12. Wang X., Yang Y.J., Jia Y.J., Zhong L., Xie M., Wang X.L., et al. The best site of transplantation of neural stem cells into brain in treatment of hypoxic-ischemic damage: experiment with newborn rats. Zhonghua Yi Xue Za Zhi 2007, 27(87):847-850.
13. Zhu W., Mao Y., Zhou L.F. Reduction of neural and vascular damage by transplantation of VEGF-secreting neural stem cells after cerebral ischemia. Acta Neurochir Suppl 2005, 95:393-397.
14. Liu C.J., Yin F., Zheng X.R., Zhang S.S., Tan J.L. The isolating culture of neural stem cells from rat's fetus brain and transfection by electroporation. Zhonghua Yi Xue Za Zhi 2009, 17(89):3007-3009.
15. Zhang S.S., Zheng X.R., Yin F., Tan J.L., Yang Y.J. Lentiviral-mediated vascular endothelial growth factor 165 gene transfer into neural stem cells promotes proliferation. Neural Regen Res 2011, 6(0):1-5.
16. Johnston M.V., Ferriero D.M., Vannucci S.J., Hagberg H. Models of cerebral palsy: which ones are best. J Child Neurol 2005, 20:984-987.
17. Zhang S.S., Zheng X.R., Yang Y.J. Adenovirus-mediated VEGF165 gene transfer has neuroprotective effects in neonatal rats following hypoxic-ischemic brain damage. Zhongguo Dang Dai Er Ke Za Zhi 2008, 10:737-742.
18. Weidner N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat 1995, 36:169-180.
19. Balduini W., De Angelis V., Mazzoni E., Cimino M. Long-lasting behavioral alterations following a hypoxic/ischemic brain injury in neonatal rats. Brain Res 2000, 24:318-325.
20. Williams R.W., Rakic P. Three-dimensional counting: an accurate and direct method to estimate numbers of cells in sectioned material. J Comp Neurol 1989, 281:335.
21. Liptak G.S., Murphy N.A. Providing a primary care medical home for children and youth with cerebral palsy. Pediatrics 2011, 128(5):e1321-e1329. Council on Children With Disabilities.
22. Surman G., Hemming K., Platt M.J., Parkes J., Green A., Hutton J., et al. Children with cerebral palsy: severity and trends over time. Paediatr Perinat Epidemiol 2009, 23(6):513-521.
23. Chen H.I., Bakshi A., Royo N.C., Magge S.N., Watson D.J. Neural stem cells as biological minipumps: a faster route to cell therapy for the CNS. Curr Stem Cell Res Ther 2007, 2:13-22.
24. Lee I.S., Jung K., Kim M., Park K.I. Neural stem cells: properties and therapeutic potentials for hypoxic-ischemic brain injury in newborn infants. Pediatr Int 2010, 52:855-865.
25. Carney B.J., Shah Cellular K. Molecular neuroscience migration and fate of therapeutic stem cells in different brain disease models. Neuroscience 2011, 197:37-47.
26. Park K.I., Ourednik J., Ourednik V., Taylor R.M., Aboody K.S., Auguste K.I., et al. Global gene and cell replacement strategies via stem cells. Gene Ther 2002, 9(10):613-624.
27. Dai N Virginie Sottile Neural stem cell approaches to CNS repair. Electron J Biol 2008, 4:79-87.
28. Nicoletti J.N., Lenzer J., Salerni E.A., Rotella F., Betancourth D., Croll S.D., et al. Vascular endothelial growth factor attenuates status epilepticus-induced behavioral impairments in rats. Epilepsy Behav 2010, 19:272-277.
29. Sköld M.K., Kanje M. Vascular endothelial growth factor in central nervous system injuries - a vascular growth factor getting nervous. Curr Neurovasc Res 2008, 5:246-259.
30. Nicoletti J.N., Shah S.K., McCloskey D.P., Rudge J.S., Scharfman H.E., Croll S.D., et al. Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus. Neuroscience 2008, 2(151):232-241.
31. Shibuya M. Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor. FEBS J 2009, 276(17):4636-4643.
32. Le Bras B., Barallobre M.J., Homman-Ludiye J., Ny A., Wyns S., Tammela T., et al. VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci 2006, 9(3):340-348.
33. Roitbak T., Li L., Cunningham L.A. Neural stem/progenitor cells promote endothelial cell morphogenesis and protect endothelial cells against ischemia via HIF-1alpha-regulated VEGF signaling. J Cereb Blood Flow Metab 2008, 28(9):1530-1542.
34. Witzenbichler B., Asahara T., Murohara T., Kearney M., Hu J.S., Isner J.M., et al. Vascular endothelial growth factor-C (VEGF-C/VEGF-2) promotes angiogenesis in the setting of tissue ischemia. Am J Pathol 1998, 153(August):381-394.
35. Branchi I., Ricceri L. Refining learning and memory assessment in laboratory rodents. An ethological perspective. Ann Ist Super Sanità 2004, 40:231-236.
36. Zohar O., Rubovitch V., Milman A., Schreiber S., Pick C.G. Behavioral consequences of minimal traumatic brain injury in mice. Acta Neurobiol Exp (Wars) 2011, 71:36-45.
37. Wenk G.L. Assessment of spatial memory using the T maze. Curr Protoc Neurosci 2001, (May). Chapter 8:Unit 8.5B.
38. Zhang L., Schallert T., Zhang Z.G., Li Q., Lu M., Chopp M., et al. A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia. J Neurosci Methods 2002, 117(June):207-214.