Evidence that 2-aminoethoxydiphenyl borate provokes fibrillation in perfused rat hearts via voltage-independent calcium channels

European Journal of Pharmacology

Volumn 681, Issue 1-3, 2012, Pages 60-67

  Wang, Peipei ^a   Umeda, Patrick K ^a   Sharifov, Oleg F ^a   Halloran, Brian A ^b   Tabengwa, Edlue ^a   Grenett, Hernan E ^a   Urthaler, Ferdinand ^a   Wolkowicz, Paul E ^a  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

2 Aminoethoxydiphenyl borate; Focal arrhythmia; Orai; SKF 96365; Ventricular fibrillation

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 2 AMINOETHOXYDIPHENYLBORANE; CALCIUM CHANNEL; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; PROTEIN ORAI3; STROMAL INTERACTION MOLECULE 1; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; BIOMECHANICS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ELECTROGRAPHY; HEART DEPOLARIZATION; HEART OUTPUT; HEART VENTRICLE FIBRILLATION; IMMUNOFLUORESCENCE TEST; NONHUMAN; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SINUS RHYTHM; WESTERN BLOTTING;

ANIMALS; BORON COMPOUNDS; CALCIUM CHANNELS; FLUORESCENT ANTIBODY TECHNIQUE; MALE; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; VENTRICULAR FIBRILLATION;

EID: 84862806821     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.01.045     Document Type: Article

References (45)

1. H. Abriel Cardiac sodium channel Nav1.5 and interacting proteins: physiology and pathophysiology J. Mol. Cell. Cardiol. 48 2010 2 11
2. D. Bai, C. del Corsso, M. Srinivas, and D.C. Spray Block of specific gap junction channel subtypes by 2-aminoethoxydiphenyl borate (2-APB) J. Pharmacol. Exp. Ther. 319 2006 1452 1458
3. W.H. Beinfield, and D. Lehr QRS-T variations in the rat electrocardiogram Am. J. Physiol. 214 1968 197 204
4. J. Ben-David, and D.P. Zipes α-Adrenoceptor stimulation and blockade modulates cesium-induced early afterdepolarizations and ventricular tachyarrhythmias in dogs Circulation 82 1990 225 233 (Pubitemid 20216334)
5. L. Birnbaumer The TRPC class of ion channels: a critical review of their roles in slow, sustained increases in intracellular Ca concentrations Annu. Rev. Pharmacol. Toxicol. 49 2009 395 426
6. W.C. Bowman, and C. Raper Spontaneous fibrillary activity of denervated muscle Nature 201 1964 160 162
7. P.A. Boyden, W. Dun, C. Barbhaiya, and H.E.D.J. Ter Keurs 2APB- and JTV519 (K201)-sensitive micro Ca waves in arrhythmogenic Purkinje cells that survive in infarcted canine heart Heart Rhythm 1 2004 218 226 (Pubitemid 38878242)
8. F.J. Braun, O. Aziz, and J.W. Putney 2-Aminoethoxydiphenyl borane activates a novel calcium-permeable cation channel Mol. Pharmacol. 63 2003 1304 1311 (Pubitemid 36627225)
9. P.S. Chen, T.J. Wu, C.T. Ting, H.S. Karagueuzian, A. Garfinkel, S.F. Lin, and J.N. Weiss A tale of two fibrillations Circulation 108 2003 2298 2303 (Pubitemid 37413532)
10. S. Corda, H.A. Spurgeon, E.G. Lakatta, M.C. Capogrossi, and R.C. Ziegelstein Endoplasmic reticulum Ca depletion unmasks a caffeine-induced Ca influx in human aortic endothelial cells Circ. Res. 77 1995 927 935
11. W.I. DeHaven, J.T. Smyth, R.R. Boyles, G.S. Bird, and J.W. Putney Complex actions of 2-aminoethoxyldiphenyl borate on store-operated calcium entry J. Biol. Chem. 283 2008 19265 19273
12. N. Doisne, V. Maupoil, P. Cosnay, and I. Findlay Catecholaminergic automatic activity in the rat pulmonary vein: electrophysiological differences between cardiac muscle in the left atrium and pulmonary vein Am. J. Physiol. 297 2009 H102 H108
13. J. Goto, A.Z. Suzuki, S. Ozaki, N. Matsumoto, T. Nakamura, E. Ebisui, A. Fleig, R. Penne, and K. Mikoshiba Two novel 2-aminoethyl diphenylborinate (2-APB) analogues differentially activate and inhibit store-operated Ca entry via STIM proteins Cell Calcium 47 2010 1 10
14. D.E. Gutstein, G.E. Morley, H. Tamaddon, D. Vaidya, M.D. Schneider, J. Chen, K.R. Chien, H. Stuhlmann, and G.I. Fishman Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin 43 Circ. Res. 88 2001 333 339 (Pubitemid 32173758)
15. M. Haïssaguerre, D.C. Shah, P. Jais, M. Shoda, J. Kautzner, T. Arentz, D. Kalushe, A. Kadish, M. Griffith, F. Gaïta, T. Yamane, S. Garrigue, M. Hocini, and J. Clémenty Role of Purkinje conducting system in triggering of idiopathic ventricular fibrillation Lancet 359 2002 677 678 (Pubitemid 34203772)
16. M. Hirose, Y. Takeishi, T. Nizeki, T. Nakada, H. Shimojo, T. Kashihara, M. Horiuchi-Hirose, I. Kubota, U. Mende, and M. Yamada Diacylglycerol kinase ζ inhibits ventricular tachyarrhythmias in a mouse model of heart failure Circ. J. 75 2011 2333 2342
17. S.J. Hong, W.W. Lin, and C.C. Chang Inhibition of the sodium channel by SKF-96365, an inhibitor of the receptor-operated calcium channel, in mouse diaphragm J. Biomed. Sci. 1 1994 172 178
18. R. Huo, Z. Li, C. Lu, Y. Xie, B. Wang, Y.J. Tu, J.T. Hu, C.Q. Xu, B.F. Yang, and D.L. Dong Inhibition of 2-aminoethoxydiphenyl borate induced rat atrial ectopic activity by antiarrhythmic drugs Cell. Physiol. Biochem. 25 2010 425 432
19. P. Jais, M. Haïssaguerre, D.C. Shah, S. Chouairi, L. Gencel, M. Hocini, and J. Clementy A focal source of atrial fibrillation treated by discrete radiofrequency ablation Circulation 95 1997 572 576 (Pubitemid 27063030)
20. B.W. Jarecki, A.D. Piekarz, J.O. Jackson II, and T.R. Cummins Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents J. Clin. Invest. 120 2010 369 378
21. Y.K. Ju, Y. Chu, H. Chaulet, D. Lai, O.L. Gervasio, R.M. Graham, M.B. Cannell, and D.G. Allen Store-operated calcium influx and expression of TRPC genes in mouse sinoatrial node Circ. Res. 100 2007 1605 1614 (Pubitemid 46897264)
22. J. Kim, S. Ghosh, H. Liu, M. Tateyama, R.S. Kass, and G.S. Pitt Calmodulin mediates Ca sensitivity of sodium channels J. Biol. Chem. 279 2004 45004 45012 (Pubitemid 39430914)
23. S.E. Lehnart, C. Terrenoire, S. Reiken, X.H.T. Wehrens, L.S. Song, E.J. Tillman, S. Mancarella, J. Coromilas, W.J. Lederer, R.S. Kass, and A.R. Marks Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias Proc. Natl. Acad. Sci. 103 2008 7906 7912
24. D.L. Lerner, K.A. Yamada, R.B. Schuessler, and J.E. Saffitz Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice Circulation 101 2000 547 552 (Pubitemid 30080870)
25. L. Mackenzie, H.L. Roderick, A. Proven, S.J. Conway, and M.D. Bootman Inositol 1,4,5-trisphosphate receptors in the heart Biol. Res. 37 2004 553 557
26. C.A. Muller, L.H. Opie, J. McCarthy, D. Hofmann, C.A. Pineda, and M. Peisach Effects of mibefradil, a novel calcium channel blocking agent with T-type activity, in acute experimental myocardial ischemia J. Am. Coll. Cardiol. 32 1998 268 274
27. ATP channel-induced improvement in postischemic functional recovery Am. J. Physiol. 288 2005 H3011 H3015
28. A. Panfilov, and A.M. Pertsov Ventricular fibrillation: evolution of the multiple-wavelet hypothesis Philos. Trans. R. Soc. Lond. A 359 2001 1315 1325
29. C. Peinelt, A. Lis, A. Beck, A. Fleig, and R. Penner 2-APB directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels J. Physiol. 586 2008 3061 3073 (Pubitemid 351984690)
30. R.P. Robichaux, D.J. Dosdall, J. Osorio, N.W. Garner, L. Li, and J. Huang Periods of highly synchronous, non-reentrant endocardial activation cycles occur during long-duration ventricular fibrillation J. Cardiovasc. Electrophysiol. 21 2010 1266 1273
31. C.J. Rothberger Neue therorien uber flimmern und flattern Klin. Wochenschr. 8 1922 82 87
32. D. Scherf, L.J. Morganbesser, E.J. Nightingale, and K.T. Schaeffler Mechanism of ventricular fibrillation Cardiologia 16 1950 232 244
33. T.J. Shuttleworth, J.L. Thompson, and O. Mignen ARC channels: a novel pathway for receptor-activated calcium entry Physiology 19 2004 355 361 (Pubitemid 39636083)
34. A. Singh, M.E. Hildebrand, E. Garcia, and T.P. Snutch The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels Br. J. Pharmacol. 160 2010 1464 1475
35. J. Stiber, A. Hawkins, Z.S. Zhang, S. Wang, J. Burch, V. Graham, C.C. Ward, M. Seth, E. Finch, N. Malouf, R.S. Williams, J.P. Eu, and P. Rosenberg STIM1 signaling controls store-operated calcium entry required for development and contractile function in skeletal muscle Nat. Cell Biol. 10 2008 688 697 (Pubitemid 351772934)
36. B.D. Stuyvers, W. Dun, S. Matkovich, V. Sorrentino, P.A. Boyden, and H.E.D.J. ter Keurs Calcium sparks and waves in canine Purkinje cells: a triple layered system of calcium activation Circ. Res. 97 2005 35 43 (Pubitemid 40982320)
37. C.D. Touchberry, C.J. Elmore, T.M. Nguyen, J.J. Andresen, X. Zhao, M. Orange, N. Weisleder, M. Brotto, W.C. Claycomb, and M.J. Wacker Store-operated calcium entry is present in HL-1 cardiomyocytes and contributes to resting calcium Biochem. Biophys. Res. Commun. 416 2011 45 50
38. F. Urthaler, P.E. Wolkowicz, S.B. Digerness, K.D. Harris, and A.A. Walker MDL-28170, a membrane-permeant calpain inhibitor, attenuates stunning and PKCε proteolysis in reperfused ferret hearts Cardiovasc. Res. 35 1997 60 67 (Pubitemid 27374741)
39. S.M. Usmani, G. Fois, S. Albrecht, S. von Aulock, P. Dietl, and O.H. Wittekindt 2-APB and capsazepine-induced Ca influx stimulates clathrin-dependent endocytosis in alveolar epithelial cells Cell. Physiol. Biochem. 25 2010 91 102
40. 2-induced arrhythmias and intracellular calcium changes in cardiac myocytes by blockade of the inositol trisphosphate pathway J. Pharmacol. Exp. Ther. 331 2009 917 924
41. P.E. Wolkowicz, H.C. Wu, F. Urthaler, and D.D. Ku 2-APB induces instability in rat left atrial mechanical activity J. Cardiovasc. Pharmacol. 49 2007 325 335 (Pubitemid 46855127)
42. P.E. Wolkowicz, H.E. Grenett, H.C. Wu, D.D. Ku, and F. Urthaler A pharmacological model for calcium overload-induced tachycardia in isolated rat left atria Eur. J. Pharmacol. 576 2007 122 131 (Pubitemid 47595322)
43. P.E. Wolkowicz, J. Huang, P.K. Umeda, O.F. Sharifov, E. Tabengwa, B.A. Halloran, F. Urthaler, and H.E. Grenett Pharmacological evidence for Orai channel activation as a source of cardiac abnormal automaticity Eur. J. Pharmacol. 668 2011 208 216
44. J. Xiao, D. Liang, H. Zhao, Y. Liu, H. Zhang, X. Lu, Y. Liu, J. Li, L. Peng, and Y.H. Chen 2-Aminoethoxydiphenyl borate, a inositol 1,4,5-triphosphate receptor inhibitor, prevents atrial fibrillation Exp. Biol. Med. 235 2010 862 868
45. A.V. Zima, and L.A. Blatter Inositol-1,4,5-trisphosphate-dependent Ca signaling in cat atrial excitation-contraction coupling and arrhythmias J. Physiol. 555 2004 607 615 (Pubitemid 38404583)