Inhibition of thromboxane A2-induced arrhythmias and intracellular calcium changes in cardiac myocytes by blockade of the inositol trisphosphate pathway

Journal of Pharmacology and Experimental Therapeutics

Volumn 331, Issue 3, 2009, Pages 917-924

  Wacker, Michael J ^a   Kosloski, L M ^a   Gilbert, W J R ^b   Touchberry, C D ^a   Moore, D S ^b   Kelly, J K ^b   Brotto, M ^a   Orr, J A ^b  

^a UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 2 AMINOETHOXYDIPHENYLBORANE; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; CALCIUM; GENTAMICIN; INOSITOL TRISPHOSPHATE; MESSENGER RNA; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR; HYDRAZINE DERIVATIVE; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL RABBIT; GENE EXPRESSION; HEART MUSCLE CELL; HEART VENTRICLE ARRHYTHMIA; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG ANTAGONISM; DRUG POTENTIATION; GENETICS; HEART ARRHYTHMIA; HEART ATRIUM; HEART VENTRICLE; METABOLISM; PHYSIOLOGY; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; ARRHYTHMIAS, CARDIAC; BLOTTING, WESTERN; CALCIUM; CELLS, CULTURED; HEART ATRIA; HEART VENTRICLES; HYDRAZINES; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MALE; MYOCYTES, CARDIAC; RABBITS; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THROMBOXANE A2; VASOCONSTRICTOR AGENTS;

EID: 73349134301     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.157677     Document Type: Article

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