Structure-activity relationship of the 7-hydroxy benzimidazole analogs as glycogen synthase kinase 3β inhibitor

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 5, 2012, Pages 1891-1894

  Lee, Seung Chul ^a,b   Shin, Dongkyu ^a   Cho, Joong Myung ^a   Ro, Sunggu ^a   Suh, Young Ger ^b  

^a CrystalGenomics Inc   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

7 Hydroxy benzimidazole; GSK3 inhibitor

Indexed keywords

7 HYDROXYBENZIMIDAZOLE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION;

BENZIMIDAZOLES; BINDING SITES; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84862806755     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.01.065     Document Type: Article

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