Adrenomedullin promotes human endothelial cell proliferation via HIF-1α

Molecular and Cellular Biochemistry

Volumn 365, Issue 1-2, 2012, Pages 263-273

  Chen, Li ^a,b   Qiu, Ju Hui ^a,b   Zhang, Ling Ling ^a,b   Luo, Xiang Dong ^a,b  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b State Key Laboratory of Trauma and Burns   (China)

Author keywords

Adrenomedullin (ADM); Cell proliferation; Endothelial cells; Hypoxia inducible factor 1 (HIF 1)

Indexed keywords

ADRENOMEDULLIN; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE;

AK1 GENE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GENE; HUMAN; HUMAN CELL; HYPOXIA; PFKP GENE; PGK1 GENE; PROTEIN EXPRESSION; VEGF GENE;

ADRENOMEDULLIN; CELL CYCLE; CELL HYPOXIA; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIAL CELLS; GENE EXPRESSION PROFILING; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PROCOLLAGEN-PROLINE DIOXYGENASE; RNA, MESSENGER; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84862806214     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1267-1     Document Type: Article

References (34)

1. HH Marti W Risau 1999 Angiogenesis in ischemic disease Thromb Haemost 82 Suppl 1 44 52 10695485
2. MP Fink 2000 Cytopathic hypoxia. A concept to explain organ dysfunction in sepsis Minerva Anestesiol 66 5 337 342 10965712 1:STN:280: DC%2BD3cvmtVWjug%3D%3D
3. LA Shimoda GL Semenza 2011 HIF and the lung: role of hypoxia-inducible factors in pulmonary development and disease Am J Respir Crit Care Med 183 2 152 156 10.1164/rccm.201009-1393PP 21242594 10.1164/rccm.201009-1393PP 1:CAS:528:DC%2BC3MXis1Cqsbo%3D
4. K Kitamura K Kangawa M Kawamoto Y Ichiki S Nakamura H Matsuo T Eto 1993 Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma Biochem Biophys Res Commun 192 2 553 560 10.1006/bbrc.1993.1451 8387282 10.1006/bbrc.1993.1451 1:CAS:528:DyaK3sXksVWktb0%3D
5. DR Poyner PM Sexton I Marshall DM Smith R Quirion W Born R Muff JA Fischer SM Foord 2002 International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors Pharmacol Rev 54 2 233 246 12037140 10.1124/pr.54.2.233 1:CAS:528:DC%2BD38XltVOiu7o%3D
6. D Ribatti D Guidolin MT Conconi B Nico S Baiguera PP Parnigotto A Vacca GG Nussdorfer 2003 Vinblastine inhibits the angiogenic response induced by adrenomedullin in vitro and in vivo Oncogene 22 41 6458 6461 10.1038/sj.onc.1206789 14508526 10.1038/sj.onc.1206789 1:CAS:528: DC%2BD3sXnsFant7w%3D
7. N Schwarz D Renshaw S Kapas JP Hinson 2006 Adrenomedullin increases the expression of calcitonin-like receptor and receptor activity modifying protein 2 mRNA in human microvascular endothelial cells J Endocrinol 190 2 505 514 10.1677/joe.1.06806 16899583 10.1677/joe.1.06806 1:CAS:528:DC%2BD28Xpt1Wjur8%3D
8. LK Malendowicz MT Conconi PP Parnigotto GG Nussdorfer 2003 Endogenous adrenomedullin system regulates the growth of rat adrenocortical cells cultured in vitro Regul Pept 112 1-3 27 31 12667622 10.1016/S0167-0115(03)00019-3 1:CAS:528:DC%2BD3sXitlWrtLY%3D
9. B Uzan A Villemin JM Garel M Cressent 2008 Adrenomedullin is anti-apoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway J Cell Physiol 215 1 122 128 10.1002/jcp.21294 17941085 10.1002/jcp.21294 1:CAS:528:DC%2BD1cXjt1Cgs7c%3D
10. Y Li C Jiang X Wang Y Zhang S Shibahara K Takahashi 2007 Adrenomedullin is a novel adipokine: adrenomedullin in adipocytes and adipose tissues Peptides 28 5 1129 1143 10.1016/j.peptides.2007.03.005 17433499 10.1016/j.peptides.2007. 03.005 1:CAS:528:DC%2BD2sXkslegtbs%3D
11. VA Cameron AM Fleming 1998 Novel sites of adrenomedullin gene expression in mouse and rat tissues Endocrinology 139 5 2253 2264 9564831 10.1210/en.139.5.2253 1:CAS:528:DyaK1cXivFSisrY%3D
12. IS Hwang DJ Autelitano PY Wong GP Leung F Tang 2003 Co-expression of adrenomedullin and adrenomedullin receptors in rat epididymis: distinct physiological actions on anion transport Biol Reprod 68 6 2005 2012 10.1095/biolreprod.102.011015 12606469 10.1095/biolreprod.102.011015 1:CAS:528:DC%2BD3sXks1Ggs7o%3D
13. MJ Miller A Martinez EJ Unsworth CJ Thiele TW Moody T Elsasser F Cuttitta 1996 Adrenomedullin expression in human tumor cell lines. Its potential role as an autocrine growth factor J Biol Chem 271 38 23345 23351 8798536 10.1074/jbc.271.38.23345 1:CAS:528:DyaK28XlvVCnsb4%3D
14. MK Oehler C Norbury S Hague MC Rees R Bicknell 2001 Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth Oncogene 20 23 2937 2945 10.1038/sj.onc.1204422 11420706 10.1038/sj.onc.1204422 1:CAS:528: DC%2BD3MXktlSjt7c%3D
15. T Miseki H Kawakami M Natsuizaka S Darmanin HY Cui J Chen Q Fu F Okada M Shindo F Higashino M Asaka J Hamuro M Kobayashi 2007 Suppression of tumor growth by intra-muscular transfer of naked DNA encoding adrenomedullin antagonist Cancer Gene Ther 14 1 39 44 10.1038/sj.cgt.7700979 16841081 10.1038/sj.cgt. 7700979 1:CAS:528:DC%2BD28XhtlShsLvE
16. U Berchner-Pfannschmidt S Frede C Wotzlaw J Fandrey 2008 Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing Eur Respir J 32 1 210 217 10.1183/09031936.00013408 18591338 10.1183/09031936.00013408 1:CAS:528:DC%2BD1cXptVGqtLg%3D
17. S Cormier-Regard SV Nguyen WC Claycomb 1998 Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes J Biol Chem 273 28 17787 17792 9651380 10.1074/jbc.273.28.17787 1:CAS:528:DyaK1cXkvFartrs%3D
18. M Nakayama K Takahashi O Murakami K Shirato S Shibahara 1998 Induction of adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells Biochem Biophys Res Commun 243 2 514 517 10.1006/bbrc.1998.8131 9480840 10.1006/bbrc.1998.8131 1:CAS:528:DyaK1cXht1eksb4%3D
19. GP Liang YY Su J Chen ZC Yang YS Liu XD Luo 2009 Analysis of the early adaptive response of endothelial cells to hypoxia via a long serial analysis of gene expression Biochem Biophys Res Commun 384 4 415 419 10.1016/j.bbrc.2009.04. 160 19427837 10.1016/j.bbrc.2009.04.160 1:CAS:528:DC%2BD1MXmsVCgsb8%3D
20. CF MacManus EL Campbell S Keely A Burgess DJ Kominsky SP Colgan 2011 Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization FASEB J 25 6 1856 1864 10.1096/fj.10-170316 21350119 10.1096/fj.10-170316 1:CAS:528:DC%2BC3MXnsFyqtrs%3D
21. L Chen J Qiu C Yang X Yang X Chen J Jiang X Luo 2009 Identification of a novel estrogen receptor beta1 binding partner, inhibitor of differentiation-1, and role of ERbeta1 in human breast cancer cells Cancer Lett 278 2 210 219 10.1016/j.canlet.2009.01.008 19217708 10.1016/j.canlet.2009.01.008 1:CAS:528:DC%2BD1MXltVCqsrc%3D
22. HJ Knowles YM Tian DR Mole AL Harris 2004 Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases Circ Res 95 2 162 169 10.1161/01.RES.0000134924.89412.70 15192023 10.1161/01.RES. 0000134924.89412.70 1:CAS:528:DC%2BD2cXls1Gqtbc%3D
23. LC Moeller AM Dumitrescu S Refetoff 2005 Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes Mol Endocrinol 19 12 2955 2963 10.1210/me.2004-0542 16051672 10.1210/me.2004-0542 1:CAS:528:DC%2BD2MXht12nu77O
24. GL Semenza 2003 Targeting HIF-1 for cancer therapy Nat Rev Cancer 3 10 721 732 10.1038/nrc1187 13130303 10.1038/nrc1187 1:CAS:528:DC%2BD3sXotFCiu70%3D
25. A Kibel O Iliopoulos JA DeCaprio WG Kaelin Jr 1995 Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C Science 269 5229 1444 1446 7660130 10.1126/science.7660130 1:CAS:528:DyaK2MXnvFCkt7g%3D
26. D Guidolin G Albertin R Spinazzi E Sorato A Mascarin D Cavallo M Antonello D Ribatti 2008 Adrenomedullin stimulates angiogenic response in cultured human vascular endothelial cells: involvement of the vascular endothelial growth factor receptor 2 Peptides 29 11 2013 2023 10.1016/j.peptides.2008.07.009 18692535 10.1016/j.peptides.2008.07.009 1:CAS:528:DC%2BD1cXht12ltL7P
27. T Kitamuro K Takahashi M Nakayama O Murakami W Hida K Shirato S Shibahara 2000 Induction of adrenomedullin during hypoxia in cultured human glioblastoma cells J Neurochem 75 5 1826 1833 11032871 10.1046/j.1471-4159.2000.0751826.x 1:CAS:528:DC%2BD3cXns1ejtLs%3D
28. M Garayoa A Martínez S Lee R Pío WG An L Neckers J Trepel LM Montuenga H Ryan R Johnson M Gassmann F Cuttitta 2000 Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis Mol Endocrinol 14 6 848 862 10847587 10.1210/me.14.6.848 1:CAS:528:DC%2BD3cXlt1Wgtrk%3D
29. GL Wang GL Semenza 1993 General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia Proc Natl Acad Sci USA 90 9 4304 4308 8387214 10.1073/pnas.90.9.4304 1:CAS:528:DyaK3sXktVGru7s%3D
30. LL Nikitenko IZ MacKenzie MC Rees R Bicknell 2000 Adrenomedullin is an autocrine regulator of endothelial growth in human endometrium Mol Hum Reprod 6 9 811 819 10956553 10.1093/molehr/6.9.811 1:CAS:528:DC%2BD3cXms1yrtr0%3D
31. H Kato M Shichiri F Marumo Y Hirata 1997 Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells Endocrinology 138 6 2615 2620 9165056 10.1210/en.138.6.2615 1:CAS:528: DyaK2sXjsVekurw%3D
32. GL Semenza PH Roth HM Fang GL Wang 1994 Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1 J Biol Chem 269 38 23757 23763 8089148 1:CAS:528:DyaK2MXpt1Wnsg%3D%3D
33. P Jaakkola DR Mole YM Tian MI Wilson J Gielbert SJ Gaskell A Kriegsheim HF Hebestreit M Mukherji CJ Schofield PH Maxwell CW Pugh PJ Ratcliffe 2001 Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation Science 292 5516 468 472 10.1126/science. 10597961059796 11292861 10.1126/science.1059796 1:CAS:528:DC%2BD3MXjtVentb0%3D
34. M Ohh CW Park M Ivan MA Hoffman TY Kim LE Huang N Pavletich V Chau WG Kaelin 2000 Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein Nat Cell Biol 2 7 423 427 10.1038/35017054 10878807 10.1038/35017054 1:CAS:528:DC%2BD3cXkvFCqtrk%3D