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Volumn 420, Issue 2, 2012, Pages 467-472

Identification of a novel cis-element that regulates alternative splicing of Bcl-x pre-mRNA

Author keywords

Alternative splicing; Apoptosis; Bcl x; Exon inclusion; Exon skipping; Pre mRNA splicing

Indexed keywords

PROTEIN BCL X; PROTEIN BCL XL; PROTEIN BCL XS; UNCLASSIFIED DRUG;

EID: 84862805837     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.03.029     Document Type: Article
Times cited : (15)

References (39)
  • 1
    • 35548940665 scopus 로고    scopus 로고
    • Neuronal regulation of alternative pre-mRNA splicing
    • Li Q., Lee J.A., Black D.L. Neuronal regulation of alternative pre-mRNA splicing. Nat. Rev. Neurosci. 2007, 8:819-831.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 819-831
    • Li, Q.1    Lee, J.A.2    Black, D.L.3
  • 2
    • 79951715071 scopus 로고    scopus 로고
    • Regulation of alternative splicing by the core spliceosomal machinery
    • Saltzman A.L., Pan Q., Blencowe B.J. Regulation of alternative splicing by the core spliceosomal machinery. Genes Dev. 2011, 25:373-384.
    • (2011) Genes Dev. , vol.25 , pp. 373-384
    • Saltzman, A.L.1    Pan, Q.2    Blencowe, B.J.3
  • 3
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-messenger RNA splicing
    • Black D.L. Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 2003, 72:291-336.
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 291-336
    • Black, D.L.1
  • 4
    • 0037062982 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing and proteome expansion in metazoans
    • Maniatis T., Tasic B. Alternative pre-mRNA splicing and proteome expansion in metazoans. Nature 2002, 418:236-243.
    • (2002) Nature , vol.418 , pp. 236-243
    • Maniatis, T.1    Tasic, B.2
  • 5
    • 56749098074 scopus 로고    scopus 로고
    • Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
    • Pan Q., Shai O., Lee L.J., Frey B.J., Blencowe B.J. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat. Genet. 2008, 40:1413-1415.
    • (2008) Nat. Genet. , vol.40 , pp. 1413-1415
    • Pan, Q.1    Shai, O.2    Lee, L.J.3    Frey, B.J.4    Blencowe, B.J.5
  • 6
    • 60349104299 scopus 로고    scopus 로고
    • The spliceosome: design principles of a dynamic RNP machine
    • Wahl M.C., Will C.L., Luhrmann R. The spliceosome: design principles of a dynamic RNP machine. Cell 2009, 136:701-718.
    • (2009) Cell , vol.136 , pp. 701-718
    • Wahl, M.C.1    Will, C.L.2    Luhrmann, R.3
  • 7
    • 0032435862 scopus 로고    scopus 로고
    • Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation
    • Lopez A.J. Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation. Annu. Rev. Genet. 1998, 32:279-305.
    • (1998) Annu. Rev. Genet. , vol.32 , pp. 279-305
    • Lopez, A.J.1
  • 8
    • 1942501651 scopus 로고    scopus 로고
    • A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2
    • Shen H., Kan J.L., Ghigna C., Biamonti G., Green M.R. A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2. RNA 2004, 10:787-794.
    • (2004) RNA , vol.10 , pp. 787-794
    • Shen, H.1    Kan, J.L.2    Ghigna, C.3    Biamonti, G.4    Green, M.R.5
  • 9
    • 0345276470 scopus 로고    scopus 로고
    • A conserved signal-responsive sequence mediates activation-induced alternative splicing of CD45
    • Rothrock C., Cannon B., Hahm B., Lynch K.W. A conserved signal-responsive sequence mediates activation-induced alternative splicing of CD45. Mol. Cell 2003, 12:1317-1324.
    • (2003) Mol. Cell , vol.12 , pp. 1317-1324
    • Rothrock, C.1    Cannon, B.2    Hahm, B.3    Lynch, K.W.4
  • 10
    • 18344364099 scopus 로고    scopus 로고
    • Understanding alternative splicing: towards a cellular code
    • Matlin A.J., Clark F., Smith C.W. Understanding alternative splicing: towards a cellular code. Nat. Rev. Mol. Cell Biol. 2005, 6:386-398.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 386-398
    • Matlin, A.J.1    Clark, F.2    Smith, C.W.3
  • 11
    • 21044438900 scopus 로고    scopus 로고
    • Multiple roles of arginine/serine-rich splicing factors in RNA processing
    • Sanford J.R., Ellis J., Caceres J.F. Multiple roles of arginine/serine-rich splicing factors in RNA processing. Biochem. Soc. Trans. 2005, 33:443-446.
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 443-446
    • Sanford, J.R.1    Ellis, J.2    Caceres, J.F.3
  • 12
    • 0032038213 scopus 로고    scopus 로고
    • Arginine/serine-rich domains of SR proteins can function as activators of pre-mRNA splicing
    • Graveley B.R., Maniatis T. Arginine/serine-rich domains of SR proteins can function as activators of pre-mRNA splicing. Mol. Cell 1998, 1:765-771.
    • (1998) Mol. Cell , vol.1 , pp. 765-771
    • Graveley, B.R.1    Maniatis, T.2
  • 13
    • 0033835333 scopus 로고    scopus 로고
    • Sorting out the complexity of SR protein functions
    • Graveley B.R. Sorting out the complexity of SR protein functions. RNA 2000, 6:1197-1211.
    • (2000) RNA , vol.6 , pp. 1197-1211
    • Graveley, B.R.1
  • 14
    • 0032962535 scopus 로고    scopus 로고
    • HnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer
    • Del Gatto-Konczak F., Olive M., Gesnel M.C., Breathnach R. HnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer. Mol. Cell Biol. 1999, 19:251-260.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 251-260
    • Del Gatto-Konczak, F.1    Olive, M.2    Gesnel, M.C.3    Breathnach, R.4
  • 15
    • 0036512117 scopus 로고    scopus 로고
    • Messenger-RNA-binding proteins and the messages they carry
    • Dreyfuss G., Kim V.N., Kataoka N. Messenger-RNA-binding proteins and the messages they carry. Nat. Rev. Mol. Cell Biol. 2002, 3:195-205.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 195-205
    • Dreyfuss, G.1    Kim, V.N.2    Kataoka, N.3
  • 16
    • 0030772379 scopus 로고    scopus 로고
    • The regulation of splice-site selection, and its role in human disease
    • Cooper T.A., Mattox W. The regulation of splice-site selection, and its role in human disease. Am. J. Hum. Genet. 1997, 61:259-266.
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 259-266
    • Cooper, T.A.1    Mattox, W.2
  • 17
    • 0033033434 scopus 로고    scopus 로고
    • A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy
    • Lorson C.L., Hahnen E., Androphy E.J., Wirth B. A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy. Proc. Natl. Acad. Sci. USA 1999, 96:6307-6311.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6307-6311
    • Lorson, C.L.1    Hahnen, E.2    Androphy, E.J.3    Wirth, B.4
  • 19
    • 0035433420 scopus 로고    scopus 로고
    • Four deaths and a funeral: from caspases to alternative mechanisms
    • Leist M., Jaattela M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat. Rev. Mol. Cell Biol. 2001, 2:589-598.
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 589-598
    • Leist, M.1    Jaattela, M.2
  • 20
    • 28244442462 scopus 로고    scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease
    • Fadeel B., Orrenius S. Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease. J. Intern. Med. 2005, 258:479-517.
    • (2005) J. Intern. Med. , vol.258 , pp. 479-517
    • Fadeel, B.1    Orrenius, S.2
  • 21
    • 21244439380 scopus 로고    scopus 로고
    • Regulation of apoptosis by alternative pre-mRNA splicing
    • Schwerk C., Schulze-Osthoff K. Regulation of apoptosis by alternative pre-mRNA splicing. Mol. Cell 2005, 19:1-13.
    • (2005) Mol. Cell , vol.19 , pp. 1-13
    • Schwerk, C.1    Schulze-Osthoff, K.2
  • 22
    • 78049416081 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged
    • David C.J., Manley J.L. Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev. 2010, 24:2343-2364.
    • (2010) Genes Dev. , vol.24 , pp. 2343-2364
    • David, C.J.1    Manley, J.L.2
  • 24
    • 4644299291 scopus 로고    scopus 로고
    • Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications
    • Akgul C., Moulding D.A., Edwards S.W. Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications. Cell Mol. Life Sci. 2004, 61:2189-2199.
    • (2004) Cell Mol. Life Sci. , vol.61 , pp. 2189-2199
    • Akgul, C.1    Moulding, D.A.2    Edwards, S.W.3
  • 25
    • 0034722884 scopus 로고    scopus 로고
    • Bcl-2 family proteins as targets for anticancer drug design
    • Huang Z. Bcl-2 family proteins as targets for anticancer drug design. Oncogene 2000, 19:6627-6631.
    • (2000) Oncogene , vol.19 , pp. 6627-6631
    • Huang, Z.1
  • 26
    • 0035844238 scopus 로고    scopus 로고
    • Modification of alternative splicing of Bcl-x pre-mRNA in prostate and breast cancer cells. analysis of apoptosis and cell death
    • Mercatante D.R., Bortner C.D., Cidlowski J.A., Kole R. Modification of alternative splicing of Bcl-x pre-mRNA in prostate and breast cancer cells. analysis of apoptosis and cell death. J. Biol. Chem. 2001, 276:16411-16417.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16411-16417
    • Mercatante, D.R.1    Bortner, C.D.2    Cidlowski, J.A.3    Kole, R.4
  • 28
    • 37149011077 scopus 로고    scopus 로고
    • Emetine regulates the alternative splicing of Bcl-x through a protein phosphatase 1-dependent mechanism
    • Boon-Unge K., Yu Q., Zou T., Zhou A., Govitrapong P., Zhou J. Emetine regulates the alternative splicing of Bcl-x through a protein phosphatase 1-dependent mechanism. Chem. Biol. 2007, 14:1386-1392.
    • (2007) Chem. Biol. , vol.14 , pp. 1386-1392
    • Boon-Unge, K.1    Yu, Q.2    Zou, T.3    Zhou, A.4    Govitrapong, P.5    Zhou, J.6
  • 29
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med. 1997, 3:614-620.
    • (1997) Nat. Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 30
    • 0034326272 scopus 로고    scopus 로고
    • Bcl-xL in prostate cancer cells: effects of overexpression and down-regulation on chemosensitivity
    • Lebedeva I., Rando R., Ojwang J., Cossum P., Stein C.A. Bcl-xL in prostate cancer cells: effects of overexpression and down-regulation on chemosensitivity. Cancer Res. 2000, 60:6052-6060.
    • (2000) Cancer Res. , vol.60 , pp. 6052-6060
    • Lebedeva, I.1    Rando, R.2    Ojwang, J.3    Cossum, P.4    Stein, C.A.5
  • 33
    • 78650930370 scopus 로고    scopus 로고
    • The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x
    • Shkreta L., Michelle L., Toutant J., Tremblay M.L., Chabot B. The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x. J. Biol. Chem. 2011, 286:331-340.
    • (2011) J. Biol. Chem. , vol.286 , pp. 331-340
    • Shkreta, L.1    Michelle, L.2    Toutant, J.3    Tremblay, M.L.4    Chabot, B.5
  • 35
    • 0028979438 scopus 로고
    • Overexpression of Bcl-XS sensitizes MCF-7 cells to chemotherapy-induced apoptosis
    • Sumantran V.N., Ealovega M.W., Nunez G., Clarke M.F., Wicha M.S. Overexpression of Bcl-XS sensitizes MCF-7 cells to chemotherapy-induced apoptosis. Cancer Res. 1995, 55:2507-2510.
    • (1995) Cancer Res. , vol.55 , pp. 2507-2510
    • Sumantran, V.N.1    Ealovega, M.W.2    Nunez, G.3    Clarke, M.F.4    Wicha, M.S.5
  • 36
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • Adams J.M., Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 2007, 26:1324-1337.
    • (2007) Oncogene , vol.26 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 37
    • 25144499098 scopus 로고    scopus 로고
    • Silencing Bcl-X(L) in cancer therapy
    • Kim K. Silencing Bcl-X(L) in cancer therapy. Cancer Biol. Ther. 2005, 4:398-399.
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 398-399
    • Kim, K.1
  • 38
    • 0042121256 scopus 로고    scopus 로고
    • Mfold web server for nucleic acid folding and hybridization prediction
    • Zuker M. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 2003, 31:3406-3415.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3406-3415
    • Zuker, M.1
  • 39
    • 79955379829 scopus 로고    scopus 로고
    • RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice site
    • Kar A., Fushimi K., Zhou X., Ray P., Shi C., Chen X., Liu Z., Chen S., Wu J.Y. RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice site. Mol. Cell Biol. 2011, 31:1812-1821.
    • (2011) Mol. Cell Biol. , vol.31 , pp. 1812-1821
    • Kar, A.1    Fushimi, K.2    Zhou, X.3    Ray, P.4    Shi, C.5    Chen, X.6    Liu, Z.7    Chen, S.8    Wu, J.Y.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.