The SSRI citalopram affects fetal thalamic axon responsiveness to netrin-1 in vitro independently of SERT antagonism

Neuropsychopharmacology

Volumn 37, Issue 8, 2012, Pages 1879-1884

  Bonnin, Alexandre ^a   Zhang, Le ^a   Blakely, Randy D ^b   Levitt, Pat ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

antidepressants; brain development; citalopram; serotonin; sigma 1 receptor; SSRI

Indexed keywords

CITALOPRAM; NETRIN 1; PAROXETINE; SEROTONIN; SIGMA 1 OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; EMBRYO; FEMALE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NERVE FIBER; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THALAMUS;

ANIMALS; AXONS; CITALOPRAM; COCULTURE TECHNIQUES; FEMALE; FETUS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; MICE, TRANSGENIC; NERVE GROWTH FACTORS; PAROXETINE; RECEPTORS, SIGMA; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; THALAMUS; TUMOR SUPPRESSOR PROTEINS;

EID: 84862804799     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.35     Document Type: Article

References (43)

1. Ansorge MS, Morelli E, Gingrich JA (2008). Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice. J Neurosci 28: 199-207.
2. Ansorge MS, Zhou M, Lira A, Hen R, Gingrich JA (2004). Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science 306: 879-881. (Pubitemid 39446998)
3. Aridor M, Fish KN (2009). Selective targeting of ER exit sites supports axon development. Traffic 10: 1669-1684.
4. Bashaw GJ, Klein R (2010). Signaling from axon guidance receptors. Cold Spring Harb Perspect Biol 2: a001941.
5. Bonnin A (2010). Guidance and outgrowth assays for embryonic thalamic axons. In: Doering LC (ed). Protocols for Neural Cell Culture. Springer, USA, 329-341.
6. Bonnin A, Goeden N, Chen K, Wilson ML, King J, Shih JC et al (2011). A transient placental source of serotonin for the fetal forebrain. Nature 472: 347-350.
7. Bonnin A, Torii M, Wang L, Rakic P, Levitt P (2007). Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci 10: 588-597. (Pubitemid 46652450)
8. Bouchard JF, Moore SW, Tritsch NX, Roux PP, Shekarabi M, Barker PA et al (2004). Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: a novel mechanism regulating commissural axon extension. J Neurosci 24: 3040-3050. (Pubitemid 38405751)
9. Braisted JE, Catalano SM, Stimac R, Kennedy TE, Tessier-Lavigne M, Shatz CJ et al (2000). Netrin-1 promotes thalamic axon growth and is required for proper development of the thalamocortical projection. J Neurosci 20: 5792-5801. (Pubitemid 30636908)
10. Bruning G, Liangos O (1997). Transient expression of the serotonin transporter in the developing mouse thalamocortical system. Acta Histochem 99: 117-121. (Pubitemid 27191412)
11. Bruning G, Liangos O, Baumgarten HG (1997). Prenatal development of the serotonin transporter in mouse brain. Cell Tissue Res 289: 211-221. (Pubitemid 27326645)
12. Casper RC, Fleisher BE, Lee-Ancajas JC, Gilles A, Gaylor E, DeBattista A et al (2003). Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy. J Pediatr 142: 402-408. (Pubitemid 36521227)
13. Gaspar P, Cases O, Maroteaux L (2003). The developmental role of serotonin: news from mouse molecular genetics. Nat Rev Neurosci 4: 1002-1012. (Pubitemid 37486676)
14. Gross C, Zhuang X, Stark K, Ramboz S, Oosting R, Kirby L et al (2002). Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature 416: 396-400. (Pubitemid 34272867)
15. Hashimoto K (2010). [Role of sigma-1 receptors in neural plasticity and in antipsychotic action]. Nihon Shinkei Seishin Yakurigaku Zasshi 30: 123-127.
16. Hayashi T, Su TP (2007). Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival. Cell 131: 596-610. (Pubitemid 350017760)
17. Hendrick V, Stowe ZN, Altshuler LL, Hwang S, Lee E, Haynes D (2003). Placental passage of antidepressant medications. Am J Psychiatry 160: 993-996. (Pubitemid 41079587)
18. Henry LK, Field JR, Adkins EM, Parnas ML, Vaughan RA, Zou MF et al (2006). Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants. J Biol Chem281: 2012-2023. (Pubitemid 43845789)
19. Hong K, Nishiyama M, Henley J, Tessier-Lavigne M, Poo M (2000). Calcium signalling in the guidance of nerve growth by netrin-1. Nature 403: 93-98. (Pubitemid 30038528)
20. Lebrand C, Cases O, Adelbrecht C, Doye A, Alvarez C, El Mestikawy S et al (1996). Transient uptake and storage of serotonin in developing thalamic neurons. Neuron 17: 823-835. (Pubitemid 26424011)
21. Lebrand C, Cases O, Wehrle R, Blakely RD, Edwards RH, Gaspar P (1998). Transient developmental expression of monoamine transporters in the rodent forebrain. J Comp Neurol 401: 506-524. (Pubitemid 28509882)
22. Lopez-Bendito G, Molnar Z (2003). Thalamocortical development: how are we going to get there? Nat Rev Neurosci 4: 276-289. (Pubitemid 37271373)
23. Martin KC (2004). Local protein synthesis during axon guidance and synaptic plasticity. Curr Opin Neurobiol 14: 305-310.
24. Maurice T, Su TP (2009). The pharmacology of sigma-1 receptors. Pharmacol Ther 124: 195-206.
25. Mavlyutov TA, Epstein ML, Andersen KA, Ziskind-Conhaim L, Ruoho AE (2010). The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study. Neuroscience 167: 247-255.
26. Moore SW, Correia JP, Lai Wing Sun K, Pool M, Fournier AE, Kennedy TE (2008). Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1. Development 135: 2855-2864.
27. Nakashiba T, Ikeda T, Nishimura S, Tashiro K, Honjo T, Culotti JG et al (2000). Netrin-G1: a novel glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from classical netrins. J Neurosci 20: 6540-6550.
28. Narboux-Neme N, Pavone LM, Avallone L, Zhuang X, Gaspar P (2008). Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs). Neuropharmacology 55: 994-1005.
29. Narita N, Hashimoto K, Tomitaka S, Minabe Y (1996). Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain. Eur J Pharmacol 307: 117-119. (Pubitemid 26226293)
30. Nishimura T, Ishima T, Iyo M, Hashimoto K (2008). Potentiation of nerve growth factor-induced neurite outgrowth by fluvoxamine: role of sigma-1 receptors, IP3 receptors and cellular signaling pathways. PLoS One 3: e2558.
31. Nishiyama M, Hoshino A, Tsai L, Henley JR, Goshima Y, Tessier- Lavigne M et al (2003). Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning. Nature 423: 990-995. (Pubitemid 36806914)
32. Oberlander TF, Gingrich JA, Ansorge MS (2009). Sustained neurobehavioral effects of exposure to SSRI antidepressants during development: molecular to clinical evidence. Clin Pharmacol Ther 86: 672-677.
33. Persico AM, Mengual E, Moessner R, Hall FS, Revay RS, Sora I et al (2001). Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release. J Neurosci 21: 6862-6873. (Pubitemid 32781129)
34. Quick MW (2002). Role of syntaxin 1A on serotonin transporter expression in developing thalamocortical neurons. Int J Dev Neurosci 20: 219-224.
35. Quick MW (2003). Regulating the conducting states of a mammalian serotonin transporter. Neuron 40: 537-549.
36. Sanchez C, Meier E (1997). Behavioral profiles of SSRIs in animal models of depression, anxiety and aggression. Are they all alike? Psychopharmacology (Berl) 129: 197-205. (Pubitemid 27085389)
37. Su TP (1982). Evidence for sigma opioid receptor: binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain. J Pharmacol Exp Ther 223: 284-290.
38. Su TP, Hayashi T, Maurice T, Buch S, Ruoho AE (2010). The sigma-1 receptor chaperone as an inter-organelle signaling modulator. Trends Pharmacol Sci 31: 557-566.
39. Takebayashi M, Hayashi T, Su TP (2002). Nerve growth factor-induced neurite sprouting in PC12 cells involves sigma-1 receptors: implications for antidepressants. J Pharmacol Exp Ther 303: 1227-1237. (Pubitemid 35424409)
40. Thompson BJ, Jessen T, Henry LK, Field JR, Gamble KL, Gresch PJ et al (2011). Transgenic elimination of high-affinity antidepressant and cocaine sensitivity in the presynaptic serotonin transporter. Proc Natl Acad Sci USA 108: 3785-3790.
41. Wang GX, Poo MM (2005). Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones. Nature 434: 898-904. (Pubitemid 40559002)
42. Xiang Y, Li Y, Zhang Z, Cui K, Wang S, Yuan XB et al (2002). Nerve growth cone guidance mediated by G protein-coupled receptors. Nat Neurosci 5: 843-848. (Pubitemid 34976648)
43. Yonkers KA, Wisner KL, Stewart DE, Oberlander TF, Dell DL, Stotland N et al (2009). The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists. Gen Hosp Psychiatry 31: 403-413.