The efficacy of Chinese herbal medicine as an adjunctive therapy for colorectal cancer: A systematic review and meta-analysis

Complementary Therapies in Medicine

Volumn 20, Issue 4, 2012, Pages 240-252

  Zhong, Linda L D ^a   Chen, Hai Yong ^b   Cho, William C S ^c   Meng, Xiao ming ^b   Tong, Yao ^a  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^c QUEEN ELIZABETH HOSPITAL   (Hong Kong)

Author keywords

Adjunctive therapy; Chinese herbal medicine (CHM); Colorectal cancer; Complementary and alternative medicine (CAM); Systematic review

Indexed keywords

AI DI; ANTINEOPLASTIC AGENT; ASTRAGALUS MEMBRANACEUS EXTRACT; BA ZHEN; CHANG AI KANG FU; CISPLATIN; FLUOROURACIL; FOLINIC ACID; FU YUAN; FU ZHENG; FU ZHENG KANG AI; FU ZHENG YI AI; HERBACEOUS AGENT; HUANG QI; HYDROXYCAMPTOTHECIN; JIAN PI HUO XUE; JIAN PI XIAO JI; JIAN PI XIAO LIU; JIAN PI YI SHEN; KU YI; MATRINE; MITOMYCIN C; MU TOU HUI GLYCOSIDE; OXALIPLATIN; PORIA COCOS EXTRACT; SEMUSTINE; SHENG XUE TANG JIA WEI; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINCRISTINE; XIANG SHA LIU JUN ZI;

ANOREXIA; BIBLIOGRAPHIC DATABASE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER STAGING; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CHEMOTHERAPY INDUCED EMESIS; CHEMOTHERAPY INDUCED NAUSEA AND VOMITING; CHINESE MEDICINE; COLORECTAL CANCER; DIARRHEA; DRUG EFFICACY; DRUG SAFETY; EVIDENCE BASED MEDICINE; HUMAN; IMMUNOREGULATION; KARNOFSKY PERFORMANCE STATUS; META ANALYSIS; NAUSEA; OUTCOME ASSESSMENT; OVERALL SURVIVAL; QUALITY CONTROL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SURVIVAL RATE; SURVIVAL TIME; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT RESPONSE;

EID: 84862804303     PISSN: 09652299     EISSN: 18736963     Source Type: Journal    
DOI: 10.1016/j.ctim.2012.02.004     Document Type: Review

References (59)

1. Boyle P., Langman J.S. ABC of colorectal cancer: epidemiology. Br Med J 2000, 321(7264):805-808.
2. Hassan C., Zullo A., Laghi A., Reitano I., Taggi F., Cerro P., et al. Colon cancer prevention in Italy: cost-effectiveness analysis with CT colonography and endoscopy. Dig Liver Dis 2007, 39(3):242-250.
3. Jamal A., Siegel R., Ward E., Murray T., Xu J., Thun M.J. Cancer statistics, 2007. CA Cancer J Clin 2007, 57(1):43-66.
4. Van der Voort van Zijp J., Hoekstra H.J., Basson M.D. Evolving management of colorectal cancer. World J Gastroenterol 2008, 14(25):3956-3967.
5. Edge S., Page D.L., Balch C.M., Fleming I.D., Morrow M. AJCC cancer staging manual 2009, Springer-Verlag, New York. 6th ed.
6. Dukes C.E. The classification of cancer of the rectum. J Pathol Bacteriol 1932, 35:323-332.
7. Greene F.L., Balch C.M., Page D.L., Haller D.G., Fleming I.D., Morrow M., et al. AJCC cancer staging handbook 2002, Springer-Verlag, New York. 6th ed.
8. Rosati G., Bilancia D. Role of chemotherapy and novel biological agents in the treatment of elderly patients with colorectal cancer. World J Gastroenterol 2008, 14(12):1812-1822.
9. Figueredo A., Coombes M.E., Mukherjee S. Adjuvant therapy for completely resected stage II colon cancer. Cochrane Database Syst Rev 2008, (3):CD005390.
10. Young A., Rea D. ABC of colorectal cancer: treatment of advanced disease. Br Med J 2000, 321(18):1278-1281.
11. Barnes P.M., Powell-Griner E., McFann K., Nahin R.L. Complementary and alternative medicine use among adults: United States, 2002. Adv Data 2004, (343):1-19.
12. Sparber A., Bauer L., Curt G., Eisenberg D., Levin T., Parks S., et al. Use of complementary medicine by adult patients participating in cancer clinical trials. Oncol Nurs Forum 2000, 27(4):623-630.
13. Molassiotis A., Fernadez-Ortega P., Pud D., Ozden G., Scott J.A., Panteli V., et al. Use of complementary and alternative medicine in cancer patients: a European survey. Ann Oncol 2005, 16(4):655-663.
14. Cui Y., Shu X.O., Gao Y., Wen W., Ruan Z.X., Jin F., et al. Use of complementary and alternative medicine by Chinese women with breast cancer. Breast Cancer Res Treat 2004, 85(3):263-270.
15. Legal status of traditional medicine and complementary/alternative medicine: a worldwide review 2001, World Health Organization, Geneva.
16. Cho W.C. Supportive cancer care with Chinese medicine 2010, Springer, New York, NY.
17. Lu Q.J. Influence of fuzheng kang'ai formula on immune of large intestine cancer. J Zhejiang Univ Tradit Chin Med 2010, 34(5):688-689.
18. Ma J., Wang G.H., Cai D.F., Fa Y., Gu X.X. Clinical observation of jianpi xiaoliu decoction in preventing postoperative colorectal carcinoma recurrence and metastasis. Shanghai J Tradit Chin Med 2005, 39(1):24-25.
19. Farrell M.P., Kummar S. Phase I/IIA randomized study of PHY906, a novel herbal agent, as a modulator of chemotherapy in patients with advanced colorectal cancer. Clin Colorectal Cancer 2003, 2(4):253-256.
20. Guo Z. Clinical observation on treatment of 38 cases of postoperational large intestinal cancer by fuzheng yiai decoction combined with chemotherapy. Zhongguo Zhong Xi Yi Jie He Za Zhi 1999, 19(1):20-22.
21. Miller A.B., Hoogstraten B., StaquetM, Winkler A. Reporting results of cancer treatment. Cancer 1981, 47(1):207-214.
22. WHO handbook for reporting results of cancer treatment 1979, World Health Organization, Geneva.
23. Jadad A.R., Moore R.A., Carroll D., Jenkinson C., Reynolds D.J., Gavaghan D., et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials 1996, 17:1-12.
24. Julian H, Sally G. Cochrane handbook for systematic reviews of interventions 5.1.0. Available online at: . http://www.cochrane-handbook.org/.
25. Dersimonian R., Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986, 7(3):177-188.
26. Chen C.G. Clinical study of patients with mid-late stage carcinoma of large intestine treated by combined FOLFOX-4 chemotherapy with tonifying spleen and kidney, removing stasis and toxicity treatment 2005, Nanjing University of Chinese Medicine, Nanjing, China.
27. Guo Z.X. Clinical observation on treatment of 38 cases of postoperational large intestinal cancer by Fuzheng Yiai decoction combined with chemotherapy. Zhongguo Zhong Xi Yi Jie He Za Zhi 1999, 19(1):20-22.
28. Huang Z.F., Li H.Z., Liu J.B., Huang C.J., Shi Z.Y. Observation on efficacy of Jianpi Xiaoji decoction combined with chemotherapy in treating advanced colorectal cancer. Modern J Integr Traditional Chin Western Med 2005, 14(10):1281-1282.
29. Huang Z.F., Shi Z.Y., Li H.Z., Tan Z.Q., Zhang Z.J., Chen C. Observation of colorectal carcinoma advanced stage treated by combination of Bazhen decoction and chemotherapy. Hebei J TCM 2008, 30(12):1283-1285.
30. Li H.S., Li H.H., Tang Z.J., Zhang S., Gao F., Li G.D., et al. Effect of Chang'ai Kangfu decoction on immunity in postoperational patients with large intestine cancer. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000, 20(8):580-582.
31. Liu J., Wang W.P., Zhou Y.Y., Fang Z.Y., Hou F.G. Observation on therapeutic effect of Jianpi Huoxue herbs combined with chemotherapy in treating post-operational colonic cancer patients. Zhongguo Zhong Xi Yi Jie He Za Zhi 2005, 25(3):207-209.
32. Liu J., Wang W.P., Zhou Y.Y., Fang Z.Y., Hou F.G. Effects on immune and hemorheology effects of Jianpi Huoxue herbs combined with chemotherapy in treating post-operational colonic cancer patients. Jiangsu J Traditional Chin Med 2005, 26(7):13-14.
33. Lu Q.J. Influence of Fuzheng Kang'ai formula on immune of large intestine cancer. J Zhejiang Univ Traditional Chin Med 2010, 34(5):688-689.
34. Ma J., Wang G.H., Cai D.F., Fan Y., Gu X.X. Clinical observation of " Jianpi Xiaoliu decoction" in preventing postoperative colorectal carcinoma recurrence and metastasis. Shanghai J Traditional Chin Med 2005, 39(1):24-25.
35. Mao X.L., Huang M. Clinical observation of Jianpi Yiqi decoction in reducing the chemotherapy-induced adverse effects of postoperative colorectal cancer. J Shandong Univ Traditional Chin Med 2005, 29(2):128-129.
36. Sun L.J., Zhang C.H. Clinical study on the combined Chinese and Western medicine in treating postoperative colon cancer. Jiangsu J Traditional Chin Med 2010, 42(6):28-29.
37. Wang H.Z., Wang S.Z., Wang Y.H., Chen J.X. Clinical observation of " Mutouhui glycoside pill" in treating carcinoma of large intestine. Shanghai J Traditional Chin Med 2000, 12:16-18.
38. Wang Y., He X.Y., Li S.J. Observation on the effect of Jianpi Yishen decoction combined with chemotherapy in treating 38 cases of postoperative carcinoma of the large intestine. Gansu J TCM 2008, 21(11):20-21.
39. Wei X.F. Clinical study on advanced colorectal carcinoma treated by integrated traditional Chinese and Western medicine 2006, Shandong University of Traditional Chinese Medicine, Shandong, China.
40. Xiao Z.Q., Luo C.D. Survey on clinical effect of Fu Yun Oral Fluid on patients undergoing chemotherapy after operation on large intestine carcinoma. Liaoning J Traditional Chin Med 1998, 25(11):516-517.
41. Yang Z.Y., Liu C., Luo J., Xu L. Study on the tolerance to chemotherapy in postoperative patients with stage III colorectal cancer treated with Chinese traditional drugs and chemotherapy. Chin J Clin Oncol Rehabil 2005, 12(2):190-192.
42. Zha M.B., Tang X.Y., Wu X., Xiao M.L., Xu K., Hu Q., et al. Clinical study on Fuzheng granule in improving the quality of life of patients undergoing chemotherapy. Acta Acad Med Wannan 2006, 25(1):54-55.
43. Zhang J.W., Wang J.S. Clinical observation of Aidi injection as adjuvant therapy for postoperative colorectal cancer. Clin Med China 2004, 20(11):999-1000.
44. Zhao W.S. Observation of the therapeutic effect of chemotherapy plus traditional Chinese medicine Sheng Xue Tang Jia Wei in the treatment of advanced colorectal cancer 2006, Beijing University of Chinese Medicine, Beijing, China.
45. Zheng X.B., Sun S.H. Clinical observation of compound matrine injection combined with chemotherapy on treating postoperative colorectal cancer. Chin J Clin 2005, 33(6):27-28.
46. Lin S.Y., Liu J.D., Chang H.C., Yeh S.D., Lin C.H., Lee W. Magnolol suppresses proliferation of cultured human colon and liver cancer cells by inhibiting DNA synthesis and activating apoptosis. J Cell Biochem 2002, 84(3):532-544.
47. Gali-Muhtasib H., Diab-Assaf M., Boltze C., Al-Hmaira J., Hartig R., Roessner A., et al. Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism. Int J Oncol 2004, 25(4):857-866.
48. He B.C., Gao J.L., Luo X., Luo J., Shen J., Wang L., et al. Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/β-catenin signaling. Int J Oncol 2011, 38(2):437-445.
49. Cho W.C. Chinese versus Western medicine. Encyclopedia of cancer 2009, vol. 3:652-654. Springer, New York, NY. 2nd ed.
50. Kawakita T., Nakai S., Kumazawa Y., Miura O., Yumioka E., Nomoto K. Induction of interferon after administration of traditional Chinese medicine, xiao-chai-hu-tang (shosaiko-to). Int J Immunopharmacol 1990, 12(5):515-521.
51. Horie Y., Kato K., Kameoka S., Hamano K. Bu ji (hozai) for treatment of postoperative gastric cancer patients. Am J Chin Med 1994, 22(3-4):309-319.
52. Lin S.Y., Liu L.M., Wu L.C. Effects of Shenmai injection on immune function in stomach cancer patients after chemotherapy. Zhongguo Zhong Xi Yi Jie He Za Zhi 1995, 15(8):451-453.
53. Block K.I., Mead M.N. Immune system effects of echinacea, ginseng, and astragalus: a review. Integr Cancer Ther 2003, 2(3):247-267.
54. Cho W.C., Leung K.N. In vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cancer Lett 2007, 252(1):43-54.
55. Cho W.C., Leung K.N. In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus. J Ethnopharmacol 2007, 113(1):132-141.
56. Ries L.A., Harkins D., Krapcho M., Mariotto A., Miller B.A., Feuer E.J., et al. SEER cancer statistics review, 1975-2003 2006, National Cancer Institute, Bethesda, MD.
57. Hollen P.J., Gralla R.J., Kris M.G., Cox C., Belani C.P., Grunberg S.M., et al. Measurement of quality of life in patients with lung cancer in multicenter trials of new therapies. Psychometric assessment of the lung cancer symptom scale. Cancer 1994, 73(8):2087-2098.
58. Cho W.C., Chen H.Y. Clinical efficacy of traditional Chinese medicine as a concomitant therapy for nasopharyngeal carcinoma: a systematic review and meta-analysis. Cancer Invest 2009, 27(3):334-344.
59. Cho W.C., Chen H.Y. Transcatheter arterial chemoembolization combined with or without Chinese herbal therapy for hepatocellular carcinoma: meta-analysis. Expert Opin Investig Drugs 2009, 18(5):617-635.