Effect of azithromycin on natural killer cell function

International Immunopharmacology

Volumn 13, Issue 1, 2012, Pages 8-14

  Lin, Syh Jae ^a   Yan, Dah Chin ^a   Lee, Wen I ^a   Kuo, Ming Ling ^a   Hsiao, Hsiu Shan ^a   Lee, Pei Yzu ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Azithromycin; Interleukin 15; Natural killer cell

Indexed keywords

AZITHROMYCIN; CD16 ANTIGEN; CD56 ANTIGEN; CD69 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 15; NATURAL KILLER CELL RECEPTOR; PERFORIN; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DOWN REGULATION; DRUG EFFECT; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; AZITHROMYCIN; CELL SURVIVAL; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; HUMANS; K562 CELLS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; RECEPTORS, NATURAL KILLER CELL;

EID: 84862802690     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.02.013     Document Type: Article

References (39)

1. M. Shinkai, and B.K. Rubin Macrolides and airway inflammation in children Paediatr Respir Rev 6 2005 227 235
2. G.W. Amsden Anti-inflammatory effects of macrolides-an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions? J Antimicrob Chemother 55 2005 10 21
3. Y. Kaneko, K. Yanagihara, M. Seki, M. Kuroki, Y. Miyazaki, and Y. Hirakata Clarithromycin inhibits overproduction of muc5ac core protein in murine model of diffuse panbronchiolitis Am J Physiol Lung Cell Mol Physiol 285 2003 L847 L853
4. T. Mitsuyama, K. Hidaka, T. Furuno, and N. Hara Neutrophil-induced endothelial cell damage: inhibition by a 14-membered ring macrolide through the action of nitric oxide Int Arch Allergy Immunol 114 1997 111 115
5. A.C. Williams, H.F. Galley, A.M. Watt, and N.R. Webster Differential effects of three antibiotics on T helper cell cytokine expression J Antimicrob Chemother 56 2005 502 506
6. K. Yanagihara, K. Tomono, Y. Imamura, Y. Kaneko, M. Kuroki, and T. Sawai Effect of clarithromycin on chronic respiratory infection caused by Pseudomonas aeruginosa with biofilm formation in an experimental murine model J Antimicrob Chemother 49 2002 867 870
7. S. Mizunoe, J. Kadota, I. Tokimatsu, K. Kishi, H. Nagai, and M. Nasu Clarithromycin and azithromycin induce apoptosis of activated lymphocytes via down-regulation of Bcl-xL Int Immunopharmacol 4 2004 1201 1207
8. M. Shinkai, J. Tamaoki, H. Kobayashi, S. Kanoh, K. Motoyoshi, and T. Kute Clarithromycin delays progression of bronchial epithelial cells from G1 phase to S phase and delays cell growth via extracellular signal-regulated protein kinase suppression Antimicrob Agents Chemother 50 2006 1738 1744
9. M.A. Caligiuri Human natural killer cells Blood 112 2008 461 469
10. J.S. Orange, and Z.K. Ballas Natural killer cells in human health and disease Clin Immunol 118 2006 1 10
11. A. Diefenbach, E.R. Jensen, A.N. Jamieson, and D.H. Raulet Rae1 and H60 ligands of the NKG2D receptor stimulate tumor immunity Nature 413 2001 165 171
12. A. Moretta, C. Bottino, M.C. Mingari, R. Biassoni, and L. Moretta What is a natural killer cells Nat Immunol 3 2002 6 8
13. L.L. Lanier NK cells receptors Annu Rev Immunol 16 1998 359 370
14. M.D. Woolard, D. Hudig, L. Tabor, J.A. Ivey, and J.W. Simecka NK cells in γ-interferon-deficient mice suppress lung innate immunity against Mycoplasma spp Infect Immun 73 2005 6742 6751
15. S. Bodhankar, M.D. Woolard, X. Sun, and J.W. Simecka NK cells interfere with the generation of resistance against mycoplasma respiratory infection following nasal-pulmonary immunization J Immunol 183 2009 2622 2631
16. F. Scaglione, F. Ferrara, S. Dugnani, G. Demartini, F. Triscari, and F. Fraschini Immunostimulation by clarithromycin in healthy volunteers and chronic bronchitis patients J Chemother 5 1993 228 232
17. K. Hamada, K. Mikasa, Y. Yunou, T. Kurioka, T. Majima, and N. Narita Adjuvant effect of clarithromycin on chemotherapy for murine lung cancer Chemotherapy 46 2000 49 61
18. N.A. Karrow, J.A. McCay, R.D. Brown, D.L. Musgrove, D.R. Germolec, and K.L. White Jr. Evaluation of the immunomodulatory effects of the macrolide antibiotic, clarithromycin, in female B6C3F1 mice: a 28-day oral gavage study Drug Chem Toxicol 24 2001 19 37
19. P. Liu, H. Allaudeen, R. Chandra, K. Phillips, A. Jungnik, and J.D. Breen Comparative pharmacokinetics of azithromycin in serum and white blood cells of healthy subjects receiving a single-dose extended-release regimen versus a 3-day immediate-release regimen Antimicrob Agents Chemother 51 2007 103 109
20. E.B. Wilms, D.J. Touw, and H.G.M. Heijerman Pharmacokinetics of azithromycin in plasma, blood, polymorphonuclear neutrophils and sputum during long-term therapy in patients with cystic fibrosis Ther Drug Monit 28 2006 219 225
21. Equi, I.M. Balfour-Lynn, A. Bush, and M. Rosenthal Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial Lancet 360 2002 978 984
22. S.J. Lin, D.C. Yan, Y.J. Lee, and M.L. Kuo Role of interleukin-15 in umbilical cord blood transplantation Int Rev Immunol 27 2008 518 531
23. S.J. Lin, P.J. Cheng, Y.J. Huang, and M.L. Kuo Evaluation of interleukin(IL)-12/ IL-15 activated umbilical cord blood natural killer cell cytotoxic function by a propidium-iodide based flow cytometry Pediatr Allergy Immunol 15 2004 79 85
24. S. Kanoh, and B.K. Rubin Mechanisms of action and clinical application of macrolides as immunomodulatory medications Clin Microbiol Rev 23 2010 590 615
25. T. Tonn, S. Becker, R. Esser, D. Schwabe, and E. Seifried Cellular immunotherapy of malignancies using the clonal natural killer cell line NK-92 J Hematother Stem Cell Res 10 2001 535 544
26. S.F. Ziegler, F. Ramsdell, K.A. Hjerrild, R.J. Armitage, K.H. Grabstein, and K.B. Hennen Molecular characterization of the early activation antigen CD69: a type II membrane glycoprotein related to a family of natural killer cell activation antigens Eur J Immunol 23 1993 1643 1648
27. D. Sancho, M. Gómez, and F. Sánchez-Madrid CD69 is an immunoregulatory molecule induced following activation Trends Immunol 26 2005 136 140
28. A. Zingoni, G. Palmieri, S. Morrone, M. Carretero, M. Lopez-Botel, and M. Piccoli CD69-triggered ERK activation and functions are negatively regulated by CD94/ NKG2-A inhibitory receptor Eur J Immunol 30 2000 644 651
29. Y. Imamura, K. Yanagihara, Y. Mizuta, M. Seki, H. Ohno, and Y. Higashiyama Azithromycin inhibits MUC5AC production induced by the Pseudomonas aeruginosa autoinducer N-(3-Oxododecanoyl) homoserine lactone in NCI-H292 Cells Antimicrob Agents Chemother 48 2004 3457 3461
30. W.C. Tsai, M.L. Rodriguez, K.S. Young, J.C. Deng, V.J. Thannickal, and K. Tateda Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection Am J Respir Crit Care Med 170 2004 1331 1339
31. J.S. Orange Formation and function of the lytic NK-cell immunological synapse Nat Rev Immunol 9 2008 713 725
32. S.S. Metkar, B. Wang, M. Aguilar-Santelises, S.M. Raja, L. Uhlin-Hansen, and E. Podack Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation Immunity 16 2002 417 428
33. S. Pisegna, G. Pirozzi, M. Piccoli, L. Frati, A. Santoni, and G. Palmieri p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells Blood 104 2004 4157 4164
34. C.C. Chini, M.D. Boos, C.J. Dick, R.A. Schoon, and P.J. Leibson Regulation of p38 mitogen-activated protein kinase during NK cell activation Eur J Immunol 30 2000 2791 2798
35. S. Ikegaya, K. Inai, H. Iwasaki, H. Naiki, and T. Ueda Azithromycin reduces tumor necrosis factor-alpha production in lipopolysaccharide-stimulated THP-1 monocytic cells by modification of stress response and p38 MAPK pathway J Chemother 21 2009 396 402
36. H. Wei, J. Zhang, W. Xiao, J. Feng, R. Sun, and Z. Tian Involvement of human natural killer cells in asthma pathogenesis: natural killer 2 cells in type 2 cytokine predominance J Allergy Clin Immunol 115 2005 841 847
37. D.L. Hahn, M.B. Plane, O.S. Mahdi, and G.I. Byrne Secondary outcomes of a pilot randomized trial of azithromycin treatment for asthma PLoS Clin Trials 1 2 2006 e11
38. Z. Liu, Yan Li, Y. Cui, X. Wang, C. Guo, and Z. Huang IL-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease Inflamm Bowel Dis 15 2009 1133 1144
39. K. Takahashi, T. Aranami, M. Endoh, S. Miyake, and T. Yamamura The regulatory role of natural killer cells in multiple sclerosis Brain 127 2004 1917 1927