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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 5, 2012, Pages 2015-2019

Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors

(11) Cuny, Gregory D a Ulyanova, Natalia P a Patnaik, Debasis a Liu, Ji Feng b Lin, Xiangjie b Auerbach, Ken a Ray, Soumya S a Xian, Jun a Glicksman, Marcie A a Stein, Ross L a Higgins, Jonathan M G a

a BRIGHAM AND WOMEN S HOSPITAL (United States)

b Aberjona Laboratories Inc (United States)

Author keywords

Beta carboline; Haspin; Inhibitor; Kinase; Structure activity relationship

Indexed keywords

ACRIDINE DERIVATIVE; BETA CARBOLINE DERIVATIVE; HARMINE; HARMOL; HASPIN KINASE INHIBITOR; LDN 211898; PROTEIN SERINE THREONINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; COMPUTER MODEL; CRYSTAL STRUCTURE; DRUG POTENCY; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; HYDROGEN BOND; IN VITRO STUDY; LIVER MICROSOME; MOLECULAR DOCKING; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; CARBOLINES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROSOMES, LIVER; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84862802670 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.01.028 Document Type: Article

Times cited : (69)

References (25)

1
- 0028102764
- H. Tanaka, Y. Yoshimura, Y. Nishina, M. Nozaki, H. Nojima, and Y. Nishimune FEBS Lett. 355 1994 4
- (1994) FEBS Lett. , vol.355 , pp. 4
- Tanaka, H.¹ Yoshimura, Y.² Nishina, Y.³ Nozaki, M.⁴ Nojima, H.⁵ Nishimune, Y.⁶

2
- 0033546159
- H. Tanaka, Y. Yoshimura, M. Nozaki, K. Yomogida, J. Tsuchida, Y. Tosaka, T. Habu, T. Nakanishi, M. Okada, H. Nojima, and Y. Nishimune J. Biol. Chem. 274 1999 17049
- (1999) J. Biol. Chem. , vol.274 , pp. 17049
- Tanaka, H.¹ Yoshimura, Y.² Nozaki, M.³ Yomogida, K.⁴ Tsuchida, J.⁵ Tosaka, Y.⁶ Habu, T.⁷ Nakanishi, T.⁸ Okada, M.⁹ Nojima, H.¹⁰ Nishimune, Y.¹¹

3
- 13844252061
- J. Dai, S. Sultan, S.S. Taylor, and J.M.G. Higgins Gene Dev. 19 2005 472
- (2005) Gene Dev. , vol.19 , pp. 472
- Dai, J.¹ Sultan, S.² Taylor, S.S.³ Higgins, J.M.G.⁴

4
- 77953292660
- J.M.G. Higgins Chromosoma 119 2010 137
- (2010) Chromosoma , vol.119 , pp. 137
- Higgins, J.M.G.¹

5
- 77957736466
- F. Wang, J. Dai, J.R. Daum, E. Niedzialkowska, B. Banerjee, P.T. Stukenberg, G.J. Gorbsky, and J.M.G. Higgins Science 330 2010 231
- (2010) Science , vol.330 , pp. 231
- Wang, F.¹ Dai, J.² Daum, J.R.³ Niedzialkowska, E.⁴ Banerjee, B.⁵ Stukenberg, P.T.⁶ Gorbsky, G.J.⁷ Higgins, J.M.G.⁸

6
- 77957725753
- A.E. Kelly, C. Ghenoiu, J.Z. Xue, C. Zierhut, H. Kimura, and H. Funabiki Science 330 2010 235
- (2010) Science , vol.330 , pp. 235
- Kelly, A.E.¹ Ghenoiu, C.² Xue, J.Z.³ Zierhut, C.⁴ Kimura, H.⁵ Funabiki, H.⁶

7
- 77957731584
- Y. Yamagishi, T. Honda, Y. Tanno, and Y. Watanabe Science 330 2010 239
- (2010) Science , vol.330 , pp. 239
- Yamagishi, Y.¹ Honda, T.² Tanno, Y.³ Watanabe, Y.⁴

8
- 78649690139
- R.A. Varier, N.S. Outchkourov, P. de Graaf, F.M.A. van Schaik, H.J.L. Ensing, F. Wang, J.M.G. Higgins, G.J.P.L. Kops, and H.Th.M. Timmers EMBO J. 29 2010 3967
- (2010) EMBO J. , vol.29 , pp. 3967
- Varier, R.A.¹ Outchkourov, N.S.² De Graaf, P.³ Van Schaik, F.M.A.⁴ Ensing, H.J.L.⁵ Wang, F.⁶ Higgins, J.M.G.⁷ Kops, G.J.P.L.⁸ Timmers, H.Th.M.⁹

9
- 70849120184
- J. Dai, A.V. Kateneva, and J.M.G. Higgins J. Cell Sci. 122 2009 4168
- (2009) J. Cell Sci. , vol.122 , pp. 4168
- Dai, J.¹ Kateneva, A.V.² Higgins, J.M.G.³

10
- 73949158814
- J. Eswaran, D. Patnaik, P. Filippakopoulos, F. Wang, R.L. Stein, J.W. Murray, J.M.G. Higgins, and S. Knapp Proc. Natl. Acad. Sci. U.S.A. 48 2009 20198
- (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.48 , pp. 20198
- Eswaran, J.¹ Patnaik, D.² Filippakopoulos, P.³ Wang, F.⁴ Stein, R.L.⁵ Murray, J.W.⁶ Higgins, J.M.G.⁷ Knapp, S.⁸

11
- 73949140419
- F. Villa, P. Capasso, M. Tortorici, F. Forneris, A. de Marco, A. Mattevi, and A. Musacchio Proc. Natl. Acad. Sci. U.S.A. 48 2009 20204
- (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.48 , pp. 20204
- Villa, F.¹ Capasso, P.² Tortorici, M.³ Forneris, F.⁴ De Marco, A.⁵ Mattevi, A.⁶ Musacchio, A.⁷

12
- 84862778944
- 10.1038/onc.2011.335
- D. Huertas, M. Soler, J. Moreto, A. Villanueva, A. Martinez, A. Vidal, M. Charlton, D. Moffat, S. Patel, J. McDermott, J. Owen, D. Brotherton, D. Krige, S. Cuthill, and M. Esteller Oncogene 2011 10.1038/onc.2011.335
- (2011) Oncogene
- Huertas, D.¹ Soler, M.² Moreto, J.³ Villanueva, A.⁴ Martinez, A.⁵ Vidal, A.⁶ Charlton, M.⁷ Moffat, D.⁸ Patel, S.⁹ McDermott, J.¹⁰ Owen, J.¹¹ Brotherton, D.¹² Krige, D.¹³ Cuthill, S.¹⁴ Esteller, M.¹⁵

13
- 80052163881
- D. Balzano, S. Santaguida, A. Musacchio, and F. Villa Chem. Biol. 18 2011 966
- (2011) Chem. Biol. , vol.18 , pp. 966
- Balzano, D.¹ Santaguida, S.² Musacchio, A.³ Villa, F.⁴

14
- 58149387464
- D. Patnaik, J. Xian, M.A. Glicksman, G.D. Cuny, R.L. Stein, and J.M.G. Higgins J. Biomol. Screen. 13 2008 1025
- (2008) J. Biomol. Screen. , vol.13 , pp. 1025
- Patnaik, D.¹ Xian, J.² Glicksman, M.A.³ Cuny, G.D.⁴ Stein, R.L.⁵ Higgins, J.M.G.⁶

15
- 77954213722
- G.D. Cuny, M. Robin, N.P. Ulyanova, D. Patnaik, V. Pique, G. Casano, J.-F. Liu, X. Lin, J. Xian, M.A. Glicksman, R.L. Stein, and J.M.G. Higgins Bioorg. Med. Chem. Lett. 20 2010 3491
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 3491
- Cuny, G.D.¹ Robin, M.² Ulyanova, N.P.³ Patnaik, D.⁴ Pique, V.⁵ Casano, G.⁶ Liu, J.-F.⁷ Lin, X.⁸ Xian, J.⁹ Glicksman, M.A.¹⁰ Stein, R.L.¹¹ Higgins, J.M.G.¹²

16
- 36549040859
- J. Bain, L. Plater, M. Elliott, N. Shpiro, C.J. Hastie, H. McLauchlan, I. Klevernic, J.S.C. Arthur, D.R. Alessi, and P. Cohen Biochem. J. 408 2007 297
- (2007) Biochem. J. , vol.408 , pp. 297
- Bain, J.¹ Plater, L.² Elliott, M.³ Shpiro, N.⁴ Hastie, C.J.⁵ McLauchlan, H.⁶ Klevernic, I.⁷ Arthur, J.S.C.⁸ Alessi, D.R.⁹ Cohen, P.¹⁰

17
- 56849127175
- A. Seifert, L.A. Allan, and P.R. Clarke FEBS J. 275 2008 6268
- (2008) FEBS J. , vol.275 , pp. 6268
- Seifert, A.¹ Allan, L.A.² Clarke, P.R.³

18
- 70349947061
- N. Göckler, G. Jofre, C. Papadopoulos, U. Soppa, F.J. Tejedor, and W. Becker FEBS J. 276 2009 6324
- (2009) FEBS J. , vol.276 , pp. 6324
- Göckler, N.¹ Jofre, G.² Papadopoulos, C.³ Soppa, U.⁴ Tejedor, F.J.⁵ Becker, W.⁶

19
- 78650144287
- Y. Ogawa, Y. Nonaka, T. Goto, E. Ohnishi, T. Hiramatsu, I. Kii, M. Yoshida, T. Ikura, H. Onogi, H. Shibuya, T. Hosoya, N. Ito, and M. Hagiwara Nat. Commun. 1 2010 86
- (2010) Nat. Commun. , vol.1 , pp. 86
- Ogawa, Y.¹ Nonaka, Y.² Goto, T.³ Ohnishi, E.⁴ Hiramatsu, T.⁵ Kii, I.⁶ Yoshida, M.⁷ Ikura, T.⁸ Onogi, H.⁹ Shibuya, H.¹⁰ Hosoya, T.¹¹ Ito, N.¹² Hagiwara, M.¹³

20
- 84862822001
- Protein Data Base (PDB) ID: 3DLZ. Docking experiments were conducted using Glide XP v2.5 from Schrödinger Inc.
- Protein Data Base (PDB) ID: 3DLZ. Docking experiments were conducted using Glide XP v2.5 from Schrödinger Inc.

21
- 84862808256
- See Supplementary data for details.
- See Supplementary data for details.

22
- 33748636018
- P. Baranczewski, A. Stańczak, K. Sundberg, R. Svensson, A. Wallin, J. Jannson, P. Garberg, and H. Postlind Pharmacol. Rep. 58 2006 453
- (2006) Pharmacol. Rep. , vol.58 , pp. 453
- Baranczewski, P.¹ Stańczak, A.² Sundberg, K.³ Svensson, R.⁴ Wallin, A.⁵ Jannson, J.⁶ Garberg, P.⁷ Postlind, H.⁸

23
- 84862808255
- 50 value determinations will ultimately be needed.
- 50 value determinations will ultimately be needed.

24
- 0034924175
- J.M.G. Higgins Protein Sci. 10 2001 1677
- (2001) Protein Sci. , vol.10 , pp. 1677
- Higgins, J.M.G.¹

25
- 33947226782
- N. Kannan, S.S. Taylor, Y. Zhai, J.C. Venter, and G. Manning PLoS Biol. 5 2007 e17
- (2007) PLoS Biol. , vol.5 , pp. 17
- Kannan, N.¹ Taylor, S.S.² Zhai, Y.³ Venter, J.C.⁴ Manning, G.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.