Neutrophil gelatinase-associated lipocalin regulates intracellular accumulation of Rh123 in cancer cells

Genes to Cells

Volumn 17, Issue 3, 2012, Pages 205-217

  Wang, Li Hong ^a,b   Chang, Guo Qiang ^a   Zhang, Hong Ju ^a   Wang, Jian ^a   Lin, Ya Ni ^a   Jin, Wei Na ^a   Li, Hua Wen ^a   Gao, Wei ^a   Wang, Ruo Jun ^a   Li, Qing Hua ^a   Pang, Tian Xiang ^a  

^a INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

^b INSTITUTE OF BLOOD TRANSFUSION   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RECOMBINANT NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; RECOMBINANT PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL LYSATE; CELL STRAIN K 562; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULARLY TARGETED THERAPY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACUTE-PHASE PROTEINS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FLUORESCENT DYES; GENE KNOCKDOWN TECHNIQUES; HUMANS; LIPOCALINS; NEOPLASMS; PROTO-ONCOGENE PROTEINS; RHODAMINE 123;

EID: 84862801776     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2012.01584.x     Document Type: Article

References (31)

1. Abrams, S.L., Steelman, L.S., Shelton, J.G., Wong, E.W., Chappell, W.H., Basecke, J., Stivala, F., Donia, M., Nicoletti, F., Libra, M., Martelli, A.M. & McCubrey, J.A. (2010) The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy. Cell Cycle 9, 1781-1791.
2. Arlinghaus, R. & Leng, X. (2008) Requirement of lipocalin 2 for chronic myeloid leukemia. Leuk. Lymphoma 49, 600-603.
3. Bartsch, S. & Tschesche, H. (1995) Cloning and expression of human neutrophil lipocalin cDNA derived from bone marrow and ovarian cancer cells. FEBS Lett. 357, 255-259.
4. Devireddy, L.R., Gazin, C., Zhu, X. & Green, M.R. (2005) A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. Cell 123, 1293-1305.
5. Fang, W.K., Xu, L.Y., Lu, X.F., Liao, L.D., Cai, W.J., Shen, Z.Y. & Li, E.M. (2007) A novel alternative spliced variant of neutrophil gelatinase-associated lipocalin receptor in oesophageal carcinoma cells. Biochem. J. 403, 297-303.
6. Furutani, M., Arii, S., Mizumoto, M., Kato, M. & Imamura, M. (1998) Identification of a neutrophil gelatinase-associated lipocalin mRNA in human pancreatic cancers using a modified signal sequence trap method. Cancer Lett. 122, 209-214.
7. Guo, X., Ma, N., Wang, J., Song, J., Bu, X., Cheng, Y., Sun, K., Xiong, H., Jiang, G., Zhang, B., Wu, M. & Wei, L. (2008) Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells. BMC Cancer 8, 375.
8. Hu, R., Yan, Y., Li, Q., Lin, Y., Jin, W., Li, H., Lu, Y. & Pang, T. (2010) Increased drug efflux along with midkine gene high expression in childhood B-lineage acute lymphoblastic leukemia cells. Int. J. Hematol. 92, 105-110.
9. Iannetti, A., Pacifico, F., Acquaviva, R., Lavorgna, A., Crescenzi, E., Vascotto, C., Tell, G., Salzano, A.M., Scaloni, A., Vuttariello, E., Chiappetta, G., Formisano, S. & Leonardi, A. (2008) The neutrophil gelatinase-associated lipocalin (NGAL), a NF-kappaB-regulated gene, is a survival factor for thyroid neoplastic cells. Proc. Natl Acad. Sci. USA 105, 14058-14063.
10. Jin, W., Li, Q., Lin, Y., Lu, Y., Li, H., Wang, L., Hu, R., Ma, L., Wang, J. & Pang, T. (2011) Reversal of Imatinib resistance in BCR-ABL-positive leukemia after inhibition of the Na+/H+ exchanger. Cancer Lett. 308, 81-90.
11. Kjeldsen, L., Cowland, J.B. & Borregaard, N. (2000) Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse. Biochim. Biophys. Acta 1482, 272-283.
12. Lal, S., Mahajan, A., Chen, W.N. & Chowbay, B. (2010) Pharmacogenetics of target genes across doxorubicin disposition pathway: a review. Curr. Drug Metab. 11, 115-128.
13. Leng, X., Ding, T. & Arlinghaus, R. (2009) Requirement of lipocalin 2 for hematopoietic and solid tumor malignancies. Adv. Enzyme Regul. 49, 142-146.
14. McCubrey, J.A., Steelman, L.S., Chappell, W.H., et al. (2007a) Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim. Biophys. Acta 1773, 1263-1284.
15. McCubrey, J.A., Steelman, L.S., Franklin, R.A., Abrams, S.L., Chappell, W.H., Wong, E.W., Lehmann, B.D., Terrian, D.M., Basecke, J., Stivala, F., Libra, M., Evangelisti, C. & Martelli, A.M. (2007b) Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance. Adv. Enzyme Regul. 47, 64-103.
16. Nelson, A.M., Zhao, W., Gilliland, K.L., Zaenglein, A.L., Liu, W. & Thiboutot, D.M. (2008) Neutrophil gelatinase-associated lipocalin mediates 13-cis retinoic acid-induced apoptosis of human sebaceous gland cells. J. Clin. Invest. 118, 1468-1478.
17. Nielsen, B.S., Borregaard, N., Bundgaard, J.R., Timshel, S., Sehested, M. & Kjeldsen, L. (1996) Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases. Gut 38, 414-420.
18. Okabe, M., Unno, M., Harigae, H., Kaku, M., Okitsu, Y., Sasaki, T., Mizoi, T., Shiiba, K., Takanaga, H., Terasaki, T., Matsuno, S., Sasaki, I., Ito, S. & Abe, T. (2005) Characterization of the organic cation transporter SLC22A16: a doxorubicin importer. Biochem. Biophys. Res. Commun. 333, 754-762.
19. Rizwan, A.N. & Burckhardt, G. (2007) Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles. Pharm. Res. 24, 450-470.
20. Sauvant, C., Nowak, M., Wirth, C., Schneider, B., Riemann, A., Gekle, M. & Thews, O. (2008) Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1) in vitro and in vivo by increasing the activity of the p-glycoprotein via activation of p38. Int. J. Cancer 123, 2532-2542.
21. Schmidt-Ott, K.M., Mori, K., Li, J.Y., Kalandadze, A., Cohen, D.J., Devarajan, P. & Barasch, J. (2007) Dual action of neutrophil gelatinase-associated lipocalin. J. Am. Soc. Nephrol. 18, 407-413.
22. Sheng, Z., Wang, S.Z. & Green, M.R. (2009) Transcription and signalling pathways involved in BCR-ABL-mediated misregulation of 24p3 and 24p3R. EMBO J. 28, 866-876.
23. Shi, H., Gu, Y., Yang, J., Xu, L., Mi, W. & Yu, W. (2008) Lipocalin 2 promotes lung metastasis of murine breast cancer cells. J. Exp. Clin. Cancer Res. 27, 83.
24. Sivaprasadarao, A., Boudjelal, M. & Findlay, J.B. (1993) Lipocalin structure and function. Biochem. Soc. Trans. 21(Pt 3), 619-622.
25. Stoesz, S.P., Friedl, A., Haag, J.D., Lindstrom, M.J., Clark, G.M. & Gould, M.N. (1998) Heterogeneous expression of the lipocalin NGAL in primary breast cancers. Int. J. Cancer 79, 565-572.
26. Tan, B.K., Adya, R., Shan, X., Syed, F., Lewandowski, K.C., O'Hare, J.P. & Randeva, H.S. (2009) Ex vivo and in vivo regulation of lipocalin-2, a novel adipokine, by insulin. Diabetes Care 32, 129-131.
27. Tong, Z., Kunnumakkara, A.B., Wang, H., Matsuo, Y., Diagaradjane, P., Harikumar, K.B., Ramachandran, V., Sung, B., Chakraborty, A., Bresalier, R.S., Logsdon, C., Aggarwal, B.B., Krishnan, S. & Guha, S. (2008) Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer. Cancer Res. 68, 6100-6108.
28. Tong, Z., Wu, X., Ovcharenko, D., Zhu, J., Chen, C.S. & Kehrer, J.P. (2005) Neutrophil gelatinase-associated lipocalin as a survival factor. Biochem. J. 391, 441-448.
29. Voulgari, A. & Pintzas, A. (2009) Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic. Biochim. Biophys. Acta 1796, 75-90.
30. Wagner-Souza, K., Diamond, H.R., Ornellas, M.H., Gomes, B.E., Almeida-Oliveira, A., Abdelhay, E., Bouzas, L.F. & Rumjanek, V.M. (2008) Rhodamine 123 efflux in human subpopulations of hematopoietic stem cells: comparison between bone marrow, umbilical cord blood and mobilized peripheral blood CD34+ cells. Int. J. Mol. Med. 22, 237-242.
31. Zheng, L.T., Lee, S., Yin, G.N., Mori, K. & Suk, K. (2009) Down-regulation of lipocalin 2 contributes to chemoresistance in glioblastoma cells. J. Neurochem. 111, 1238-1251.