Integrated pharmacokinetics of major bioactive components in MCAO rats after oral administration of Huang-Lian-Jie-Du-Tang

Journal of Ethnopharmacology

Volumn 141, Issue 1, 2012, Pages 158-169

  Zhu, Huaxu ^a   Qian, Zhilei ^a   Li, Huan ^a   Guo, Liwei ^a   Pan, Linmei ^a   Zhang, Qichun ^a   Tang, Yuping ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

AUC weighting approach; Components classification; Correlation between pharmacokinetics and effect; Huang Lian Jie Du Tang; Integral pharmacokinetic

Indexed keywords

BAICALEIN; BAICALIN; BERBERINE; GENIPOSIDE; GLUTAMIC ACID; INTERLEUKIN 6; MALONALDEHYDE; ORENGEDOKU TO; PALMATINE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; CORTEX PHELLODENDRI; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG STABILITY; FRUCTUS GARDENIA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF QUANTITATION; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MEDICINAL PLANT; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; RADIX SCUTELLARIAE; RAT; RHIZOMA COPTIDIS; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOTRANSFORMATION; CARDIOVASCULAR AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; DRUG STABILITY; DRUGS, CHINESE HERBAL; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MODELS, BIOLOGICAL; PHYTOTHERAPY; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 84862798944     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.02.014     Document Type: Article

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