New cytotoxic quinolone alkaloids from fruits of Evodia rutaecarpa

Fitoterapia

Volumn 83, Issue 4, 2012, Pages 709-714

  Huang, Xin ^a   Li, Wei ^a   Yang, Xiu Wei ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Cytotoxic activity; Evodia rutaecarpa; MTT assay; Quinolone alkaloids; Rutaceae

Indexed keywords

1 METHYL 2 (1 UNDECENYL) 4(1H) QUINOLONE; 1 METHYL 2 (1,5 UNDECADIENYL) 4(1H) QUINOLONE; 1 METHYL 2 (10 PENTADECENYL) 4(1H) QUINOLONE; 1 METHYL 2 (4 NONEYL) 4(1H) QUINOLONE; 1 METHYL 2 (6 PENTADECENYL) 4(1H) QUINOLONE; 1 METHYL 2 (6 UNDECENYL) 4(1H) QUINOLONE; 1 METHYL 2 (7 CARBONYL) 9 TRIDECENYL 4(1H) QUINOLONE; 1 METHYL 2 (7 HYDROXY 9 TRIDECENYL) 4(1H) QUINOLONE; 1 METHYL 2 (PENTADECADIENYL) 4(1H) QUINOLONE; 1 METHYL 2 (TRIDECADIENYL) 4(1H) QUINOLONE; 1 METHYL 2 DECYL 4(1H) QUINOLONE; 1 METHYL 2 DODECYL 4(1H) QUINOLONE; 1 METHYL 2 NONYL 4(1H) QUINOLONE; 1 METHYL 2 PENTADECYL 4(1H) QUINOLONE; 1 METHYL 2 TETRADECYL 4(1H) QUINOLONE; ALKALOID DERIVATIVE; DIHYDROEVOCARPINE; EVOCARPINE; EVODIA FRUIT; QUINOLONE ALKALOID; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; LIVER CARCINOMA; LUNG CARCINOMA; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; SPECTROSCOPY; STOMACH CARCINOMA; TETRADIUM RUTICARPUM;

ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; EVODIA; FRUIT; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; NEOPLASMS; PHYTOTHERAPY; PLANT EXTRACTS; QUINOLONES;

EVODIA RUTAECARPA; RUTACEAE;

EID: 84862798884     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.02.009     Document Type: Article

References (21)

1. Chinese Pharmacopoeia Commission Pharmacopoeia of the People's Republic of China Volume I 2010 China Medical Science and Technology Press Beijing 160
2. T. Sugimoto, T. Miyase, M. Kuroyanagi, and A. Ueno Limonoids and quinolone alkaloids from Evodia rutaecarpa Bentham Chem Pharm Bull 36 1988 4453 4461
3. Y.Q. Tang, X.Z. Feng, and L. Huang Quinolone alkaloids from Evodia rutaecarpa Phytochemistry 43 1996 719 792
4. W.C. Chuang, C.M. Cheng, H. Chang, Y.P. Chen, and S.J. Sheu Contents of constituents in mature and immature fruits of Evodia species Planta Med 65 1999 567 571
5. J. Teng, and X.W. Yang Two new indoloquinazoline alkaloids from the unripe fruits of Evodia rutaecarpa Heterocycles 68 2007 1691 1698
6. X.W. Yang, and J. Teng Chemical constituents of the unripe fruits of Evodia rutaecarpa J Chin Pharm Sci 16 2007 20 23
7. M. Adams, A. Mahringer, O. Kunert, G. Fricker, T. Efferth, and R. Bauer Cytotoxicity and P-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa Planta Med 73 2007 1554 1557
8. M.L. Xu, G. Li, D.C. Moo, C.S. Lee, M.H. Woo, and E.S. Lee Cytotoxicity and DNA topoisomerase inhibitory activity of constituents isolated from the fruits of Evodia officinalis Arch Pharm Res 29 2006 541 547
9. M.Y. Zhao, and X.W. Yang Optimization of the extraction conditions and simultaneous quantification by RP-LC of six alkaloids in Evodiae Fructus Chromatographia 67 2008 543 550
10. X.W. Yang, H. Zhang, M. Li, L.J. Du, Z. Yang, and S.Y. Xiao Studies on the alkaloid constituents of Evodia rutaecarpa (Juss.) Benth. var. bodinaieri (Dode) Huang and their acute toxicity in mice J Asian Nat Prod Res 8 2006 697 703
11. X.W. Yang, J. Teng, Y. Wang, and W. Xu The permeability and the efflux of alkaloids of the Evodiae Fructus in the Caco-2 model Phytother Res 23 2009 56 60
12. J. Teng, and X.W. Yang A new limonoid from the fruits of Evodia rutaecarpa (Juss.) Benth Pharmazie 61 2006 1038 1040
13. M.Y. Zhao, and X.W. Yang Two new acylgluconic acids from the nearly ripe fruits of Evodia rutaecarpa J Asian Nat Prod Res 10 2008 759 763
14. A.A. Wube, A. Hüfner, C. Thomaschitz, M. Blunder, M. Kollroser, and R. Bauer Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones Bioorgan Med Chem 19 2011 567 579
15. M. Ahsan, A.I. Gray, P.G. Waterman, and J.A. Armstrong 4-Quinolinones, 2-quinolinone, 9-acridanone, and furoquinoline alkaloids from the aerial parts of Boronia bowmanii J Nat Prod 57 1994 670 672
16. H.Z. Jin, J.H. Lee, D. Lee, H.S. Lee, Y.S. Hong, and Y.H. Kim Quinolone alkaloids with inhibitory activity against nuclear factor of activated T cells from the fruits of Evodia rutaecarpa Biol Pharm Bull 27 2004 926 928
17. Y.Q. Tang, K.M. Wu, X.Z. Feng, and L. Huang Synthesis and bioaction of 2-alkyl-4(1H)-quinolone Acta Pharm Sin 33 1998 121 127
18. J.S. Ko, M.C. Rho, M.Y. Chung, H.Y. Song, J.S. Kang, and K. Kim Quinolone alkaloids, diacylglycerol acyltransferase inhibitors from the fruits of Evodia rutaecarpa Planta Med 68 2002 1131 1133
19. T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Meth 65 1983 55 63
20. L. Huang, and D.Q. Yu Application of ultraviolet spectrum in organic chemistry 1988 Science Press Beijing
21. P.Z. Cong Application of mass spectrometry in natural organic chemistry 1987 Science Press Beijing