Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl- 4(1H)-quinolones

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 1, 2011, Pages 567-579

  Wube, Abraham A ^a   Hüfner, Antje ^a   Thomaschitz, Christina ^a   Blunder, Martina ^a   Kollroser, Manfred ^b   Bauer, Rudolf ^a   Bucar, Franz ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

1 Methyl 2 alkenyl 4(1H) quinolone; Antimycobacterial; SAR; Tuberculosis

Indexed keywords

1 METHYL 2 [1' HEPTENYL] 4(1H) QUINOLONE; 1 METHYL 2 [1' OCTENYL] 4(1H) QUINOLONE; 1 METHYL 2 [1' UNDECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [1',3' PENTADECADIENYL] 4(1H) QUINOLONE; 1 METHYL 2 [1',3' TETRADECADIENYL] 4(1H) QUINOLONE; 1 METHYL 2 [10' TRIDECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [3' DECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [3' DODECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [3' TETRADECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [3' TRIDECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [4' TRIDECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [5' DECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [5' DODECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [5' PENTADECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [5' UNDECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [8' HEPTADECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [8',11' HEPTADECADIENYL] 4(1H) QUINOLONE; 1 METHYL 2 [9' EICOSENYL] 4(1H) QUINOLONE; 1 METHYL 2 [9' NONADECENYL] 4(1H) QUINOLONE; 1 METHYL 2 [9' OCTADECENYL] 4(1H) QUINOLONE; 1 METHYL 2 ALKENYL 4(1H) QUINOLONE; 1 METHYL 2 HEPTADECYL 4(1H) QUINOLONE; 1 METHYL 2 PENTADECYL 4(1H) QUINOLONE; 1 METHYL 2 TRIDECYL 4(1H) QUINOLONE; CIPROFLOXACIN; ETHAMBUTOL; EVOCARPINE; ISONIAZID; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; EMBRYO; FETUS LUNG; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM FORTUITUM; MYCOBACTERIUM PHLEI; MYCOBACTERIUM SMEGMATIS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANTITUBERCULAR AGENTS; CELL LINE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; QUINOLONES;

CORYNEBACTERINEAE; MYCOBACTERIUM FORTUITUM;

EID: 78650755969     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.10.060     Document Type: Article

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